10 Results for "

albino mouse

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "albino mouse" in MCE Product Catalog:

23
23 Cited Publications
Cat. No.: HY-N0171A
CAS No.: 83-46-5
Synonyms: β-Sitosterol (purity>98%); 22,23-Dihydrostigmasterol (purity>98%)
Beta-Sitosterol (purity>98%) is orally active. Beta-Sitosterol exhibits multiple activities, including anti-inflammatory, anticancer, antioxidant, antimicrobial, antidiabetic, antioxidant enzyme, and analgesic. Beta-Sitosterol inhibits inflammation and impaired adipogenesis in bovine mammary epithelial cells by reducing levels of ROS, TNF-α, IL-1β, and NF-κB p65 and restoring the activity of the HIF-1α/mTOR signaling pathway. Beta-Sitosterol induces apoptosis in cancer cells through ROS-mediated mitochondrial dysregulation and p53 activation. Beta-Sitosterol exerts its anticancer effects in cancer cells by activating caspase-3, caspase-8, and caspase-9, mediating PARP inactivation, MMP loss, altered Bcl-2-Bax ratio, and cytochrome c release. Beta-Sitosterol modulates macrophage polarization and reduces rheumatoid inflammation in mice. Beta-Sitosterol inhibits tumor growth in multiple mouse cancer models. Beta-Sitosterol can be used in the research of arthritis, lung cancer, breast cancer and other cancers, diabetes, etc .
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2
2 Cited Publications
Cat. No.: HY-103530
CAS No.: 123690-79-9
Purity:  ≥98.0%
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

CGP 35348 is a selective, brain penetrant, centrally active GABAB receptor antagonist with an EC50 of 34 μM. CGP 35348 shows affinity for the GABAB receptor only . CGP 35348 has a potential to improve neuromuscular coordination and spatial learning in albino mouse following neonatal brain damage .
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Cat. No.: HY-N11908
CAS No.: 115-71-9
Synonyms: cis-α-Santalol
α-Santalol (cis-α-Santalol), a naturally occurring sesquiterpene, is an orally active anticancer agent and apoptosis inducer. α-Santalol activates caspase-3 to drive apoptotic processes. >α-Santalol induces apoptosis, decreases cell viability, and causes PARP cleavage in human prostate cancer cells. α-santalol inhibits Akt/Survivin pathway to induce cell death. α-Santalol can be used for the research of prostate cancer and diabetes mellitus .
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Cat. No.: HY-176747
CAS No.: 3081-01-4
Synonyms: DMPPD
Research Areas:  

Others

7-PPD (DMPPD) is a rubber antioxidant that scavenges free radicals and inhibits the oxidative degradation of rubber chains. 7-PPD shows promise for research in tire manufacturing and rubber product processing .
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Cat. No.: HY-127165
CAS No.: 124027-47-0
Synonyms: HP 029 free base; Hydroxytacrine
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease

Velnacrine (HP 029 free base) is an inhibitor for acetylcholinesterase (AChE), with an IC50 of 3.27 μM. Velnacrine reverses the Scopolamine (HY-N0296)-induced amnesia in rat models, and exhibits acute toxicity with LD50 of 65 mg/kg .
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Cat. No.: HY-121182
CAS No.: 20283-48-1
Chalcomycin is a macrolide antibiotic, which exhibits antimicrobial activities against gram-positive Staphylococcus aureus and Streptococcus pyogenes. Chalcomycin protects mice from infection with a variety of staphylococci and streptococc, without significant toxicity (LD50 >2500 mg/kg) .
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Cat. No.: HY-176218
Target:  

Drug Derivative

Research Areas:  

Inflammation/Immunology

TTTE is a sulfone bischalcone derivative. TTTE has major anti-necrotic, anti-inflammatory and anti-fibrotic activities. TTTE exerts regulatory effects by downregulating key molecules such as Caspase-3, TNF-α, NF-κB and TGF-β. TTTE can be used in the study of liver injury .
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Cat. No.: HY-103530R
CAS No.: 123690-79-9
Research Areas:  

Neurological Disease

CGP35348 (Standard) is the analytical standard of CGP35348. This product is intended for research and analytical applications. CGP 35348?is a selective, brain penetrant, centrally active GABAB receptor antagonist with an EC50 of 34 μM.?CGP 35348 shows affinity for the GABAB receptor only . CGP 35348 has a potential to improve neuromuscular coordination and spatial learning in albino mouse following neonatal brain damage .
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Cat. No.: HY-120462
CAS No.: 1254834-91-7
Research Areas:  

Infection

Genz-669178 is an inhibitor for dihydroorotate dehydrogenase (DHODH) with IC50 of 0.015-0.05 μM in Plasmodium spp.. Genz-669178 inhibits P. berghei, P. falciparum strains 3D7 and Dd2 with IC50 of 0.068, 0.008 and 0.01 μM, respectively. Genz-669178 exhibits anti-malarial efficacy in P. berghei-infected mice with ED50 of 13-21 mg/kg/day. Genz-669178 exhibits good pharmacokinetic characteristics in mice .
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Cat. No.: HY-P702479
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Tyr; Tyrosinase; EC 1.14.18.1; albino locus protein; Monophenol monooxygenase; Tumor rejection antigen AB; SK29-AB; LB24-AB
Species:  
Mouse
Source:  
E. coli Cell-free
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