123690-79-9
123690-79-9
Chemical Structure
CGP35348
- CAS No.: 123690-79-9
- Formula:C8H20NO4P
- Molecular Weight:225.22
IUPAC Name: (3-aminopropyl)(diethoxymethyl)phosphinic acid
InChIKey: QIIVUOWTHWIXFO-UHFFFAOYSA-N
SMILES: O=P(C(OCC)OCC)(CCCN)O
Biological Activity: CGP 35348 is a selective, brain penetrant, centrally active GABAB receptor antagonist with an EC50 of 34 μM. CGP 35348 shows affinity for the GABAB receptor only[1]. CGP 35348 has a potential to improve neuromuscular coordination and spatial learning in albino mouse following neonatal brain damage[2].
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CGP35348 | 98.0% | CGP 35348 is a selective, brain penetrant, centrally active GABAB receptor antagonist with an EC50 of 34 μM. CGP 35348 shows affinity for the GABAB receptor only. CGP 35348 has a potential to improve neuromuscular coordination and spatial learning in albino mouse following neonatal brain damage. | ||||||||||||||||||||
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CGP35348 (Standard) | ≥98% | CGP35348 (Standard) is the analytical standard of CGP35348. This product is intended for research and analytical applications. CGP 35348?is a selective, brain penetrant, centrally active GABAB receptor antagonist with an EC50 of 34 μM.?CGP 35348 shows affinity for the GABAB receptor only. CGP 35348 has a potential to improve neuromuscular coordination and spatial learning in albino mouse following neonatal brain damage. | ||||||||||||||||||||
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References
- [1]. H R Olpe,et al. CGP 35348: a centrally active blocker of GABAB receptors. CGP 35348: a centrally active blocker of GABAB receptors [Content Brief]
- [2]. Q Gillani, et al. CGP 35348, GABA B receptor antagonist, has a potential to improve neuromuscular coordination and spatial learning in albino mouse following neonatal brain damage. Biomed Res Int. 2014;2014:295215. [Content Brief]
Keywords
