SKF 97541
SKF 97541 (CGP 35024) is a potent and selective GABAB agonist that can induce hyperpotential. SKF 97541 has antiepileptic activity.
For research use only. We do not sell to patients.
- CAS No.: 127729-35-5
- Formula: C4H12NO2P
- Molecular Weight:137.12
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CHO-K1 | EC50 |
41 nM
Compound: 2
|
Agonist activity at human recombinant GABABreceptor expressed in CHO-K1 cells assessed as inhibition of intracellular calcium release by FLIPR
Agonist activity at human recombinant GABABreceptor expressed in CHO-K1 cells assessed as inhibition of intracellular calcium release by FLIPR
|
[PMID: 18578471] |
Chemical Information
-
CAS No. 127729-35-5
-
Molecular Weight 137.12
-
Formula C4H12NO2P
-
SMILES
O=P(C)(CCCN)O
-
Synonyms
CGP 35024
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Bon C, et al. Electrophysiological actions of GABAB agonists and antagonists in rat dorso-lateral septal neurones in vitro. Br J Pharmacol. 1996 Jun;118(4):961-7. [Content Brief]
[2]. Smirnova EY, et al. Presynaptic GABAB receptors underlie the antiepileptic effect of low-frequency electrical stimulation in the 4-aminopyridine model of epilepsy in brain slices of young rats. Brain Stimul. 2020 Sep-Oct;13(5):1387-1395. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SKF 97541 Related Classifications
HY-100915 Related Classifications
Powered by Bioz