115-71-9
Chemical Structure
α-Santalol
Synonym(s): cis-α-Santalol
- CAS No.: 115-71-9
- Formula:C15H24O
- Molecular Weight:220.35
InChIKey: PDEQKAVEYSOLJX-XRNHCGLHSA-N
SMILES: CC12C(C3)[C@@H]1CC3[C@](C)2CC/C=C(C)\CO
Biological Activity: α-Santalol (cis-α-Santalol), a naturally occurring sesquiterpene, is an orally active anticancer agent and apoptosis inducer. α-Santalol activates caspase-3 to drive apoptotic processes. >α-Santalol induces apoptosis, decreases cell viability, and causes PARP cleavage in human prostate cancer cells. α-santalol inhibits Akt/Survivin pathway to induce cell death. α-Santalol can be used for the research of prostate cancer and diabetes mellitus[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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α-Santalol | 97.62% | α-Santalol (cis-α-Santalol), a naturally occurring sesquiterpene, is an orally active anticancer agent and apoptosis inducer. α-Santalol activates caspase-3 to drive apoptotic processes. >α-Santalol induces apoptosis, decreases cell viability, and causes PARP cleavage in human prostate cancer cells. α-santalol inhibits Akt/Survivin pathway to induce cell death. α-Santalol can be used for the research of prostate cancer and diabetes mellitus. | ||||||||||||||||||||
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- [1]. Bommareddy A, et al. α-Santalol, a derivative of sandalwood oil, induces apoptosis in human prostate cancer cells by causing caspase-3 activation. Phytomedicine. 2012;19(8-9):804-811. [Content Brief]
- [2]. Okugawa H, et al. Effect of α-santalol and β-santalol from sandalwood on the central nervous system in mice. Phytomedicine. 1995;2(2):119-126. [Content Brief]
- [3]. Misra BB, et al. Evaluation of in vivo anti-hyperglycemic and antioxidant potentials of α-santalol and sandalwood oil. Phytomedicine. 2013;20(5):409-416. [Content Brief]
- [4]. Bommareddy A, McGlynn D, Lewis M, Lockus L, Seward J, Hong KL, VanWert AL, Dwivedi C. Akt/survivin pathway inhibition enhances the apoptotic cell death-induced by alpha-santalol in human prostate cancer cells. Fitoterapia. 2020 Jun;143:104552. [Content Brief]
Keywords
