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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
52 Results for "
amyloid b
" in MedChemExpress (MCE) Product Catalog:
Products (52)
52 Results for "amyloid b" in MCE Product Catalog:
12
12 Publications Verification
Cat. No.: HY-N0373
CAS No.: 58749-23-8
6
6 Cited Publications
4
4 Cited Publications
Cat. No.: HY-N0044
CAS No.: 52286-59-6
Synonyms: Ginsenoside B2; Panaxoside Re; Sanchinoside Re
Category:
Panax ginseng C. A. Meyer Triterpenes Neurological Disease Terpenoids Plants Endogenous metabolite Disease Research Fields Araliaceae Cancer
Target:
2
2
2 Cited Publications
Cat. No.: HY-P7747
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CTSB; Keratolytic Winter Erythema (Oudtshoorn Skin Disease); Cathepsin B; Epididymis Secretory Sperm Binding Protein; APP Secretase; amyloid Precursor Protein Secretase; Cathepsin B1; Cysteine Protease; APPS; RECEUP; CPSB; KWE
2
2 Cited Publications
Cat. No.: HY-P7993A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CTSB; Keratolytic Winter Erythema (Oudtshoorn Skin Disease); Cathepsin B; Epididymis Secretory Sperm Binding Protein; APP Secretase; amyloid Precursor Protein Secretase; Cathepsin B1; Cysteine Protease; APPS; RECEUP; CPSB; KWE
1
1 Cited Publications
Cat. No.: HY-148089
CAS No.: 1637600-16-8
Target:
Research Areas:
Eplontersen is a triantennary N-acetyl galactosamine (GalNAc3-7a)-conjugated antisense oligonucleotide targeting transthyretin (TTR) mRNA to inhibit production of both variant and wild-type TTR protein. Misfolded TTR induces amyloid fibrils formation in the heart and peripheral nerves, leads to amyloid TTR (ATTR) amyloidosis diseases .
1
1 Cited Publications
Target:
Research Areas:
Eplontersen sodium the sodium salt form of Eplontersen (HY-148089). Eplontersen sodium is a triantennary N-acetyl galactosamine (GalNAc3-7a)-conjugated antisense oligonucleotide targeting transthyretin (TTR) mRNA to inhibit production of both variant and wild-type TTR protein. Misfolded TTR induces amyloid fibrils formation in the heart and peripheral nerves, leads to amyloid TTR (ATTR) amyloidosis diseases .
1
1 Cited Publications
Cat. No.: HY-P78682
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CTSB; Keratolytic Winter Erythema (Oudtshoorn Skin Disease); Cathepsin B; Epididymis Secretory Sperm Binding Protein; APP Secretase; amyloid Precursor Protein Secretase; Cathepsin B1; Cysteine Protease; APPS; RECEUP; CPSB; KWE
Synonyms: Anle138b
Target:
Research Areas:
Emrusolmin (Anle138b), an oligomeric aggregation inhibitor, blocks the formation of pathological aggregates of prion protein (PrPSc) and of α-synuclein (α-syn). Emrusolmin strongly inhibits oligomer accumulation, neuronal degeneration, and disease progression in vivo. Emrusolmin has low toxicity and an excellent oral bioavailability and blood-brain-barrier penetration. Emrusolmin blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology .
Cat. No.: HY-P2358
CAS No.: 1001405-52-2
Cat. No.: HY-N7046
CAS No.: 142797-34-0
Synonyms: Silibinin B
Cat. No.: HY-N1570
CAS No.: 34175-96-7
Category:
other families Ketones, Aldehydes, Acids Plants Disease Research Fields Inflammation/Immunology Pteridium aquilinum Pteridiaceae
Target:
Cat. No.: HY-P990301
Target:
Research Areas:
Cat. No.: HY-P991046
Target:
Research Areas:
Cat. No.: HY-N1280
CAS No.: 129280-33-7
Category:
Flavonoids Leguminosae Phenols Polyphenols Plants Glycyrrhiza uralensis Fisch. Isoflavones
Target:
Cat. No.: HY-N13742
CAS No.: 219565-74-9
Synonyms: Dihydrohonokiol
Target:
Cat. No.: HY-W117986
CAS No.: 352525-91-8
Research Areas:
Aβ aggregation-IN-1 (Compound 1b) is a β-amyloid aggregation inhibitor/depolymerizer, with IC50 values of 3.92 μM and 7.19 μM, respectively. Aβ aggregation-IN-1 inhibits the activation of preformed β-amyloid fibrils, reactive oxygen species (ROS) and Caspase-3. Aβ aggregation-IN-1 can be used in research related to Alzheimer's disease .
Cat. No.: HY-DY1045
CAS No.: 863918-78-9
Solvent and concentration: DMSO: 5 mg/mL
Cat. No.: HY-151962
CAS No.: 2911640-63-4
Research Areas:
JNK3 inhibitor-5 (Compound 22b) is a potent and selective JNK3 inhibitor with an IC50 of 0.379 nM. JNK3 inhibitor-5 effectively protects the neuronal cells against amyloid beta-induced apoptosis. JNK3 inhibitor-5 has a high cell permeability and is predicted as BBB permeable .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
