219565-74-9
219565-74-9
Chemical Structure
Dihydrohonokiol B
Synonym(s): Dihydrohonokiol
- CAS No.: 219565-74-9
- Formula:C18H20O2
- Molecular Weight:268.35
InChIKey: IBKNHHZQPPUDQJ-UHFFFAOYSA-N
SMILES: OC1=CC=C(CCC)C=C1C2=CC(CC=C)=C(O)C=C2
Biological Activity: Dihydrohonokiol B (Dihydrohonokiol) is an anxiolytic agent. Dihydrohonokiol B can reduce the neurotoxicity induced by amyloid β protein by stimulating the GABAC receptor. Dihydrohonokiol B can be used in the research of neurodegenerative diseases such as Alzheimer's disease[1][2].
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Dihydrohonokiol B | 98.48% | Dihydrohonokiol B (Dihydrohonokiol) is an anxiolytic agent. Dihydrohonokiol B can reduce the neurotoxicity induced by amyloid β protein by stimulating the GABAC receptor. Dihydrohonokiol B can be used in the research of neurodegenerative diseases such as Alzheimer's disease. | ||||||||||||||||||||
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References
- [1]. Esumi T, et al. Efficient synthesis and structure-activity relationship of honokiol, a neurotrophic biphenyl-type neolignan. Bioorg Med Chem Lett. 2004 May 17;14(10):2621-5. [Content Brief]
- [2]. Liu B, et al. Anxiolytic agent, dihydrohonokiol-B, recovers amyloid beta protein-induced neurotoxicity in cultured rat hippocampal neurons. Neurosci Lett. 2005 Aug 12-19;384(1-2):44-7. [Content Brief]
Keywords
