129280-33-7
129280-33-7
Chemical Structure
Semilicoisoflavone B
- CAS No.: 129280-33-7
- Formula:C20H16O6
- Molecular Weight:352.34
IUPAC Name: 5,7,8'-trihydroxy-2',2'-dimethyl-2'H,4H-[3,6'-bichromen]-4-one
InChIKey: LWZACZCRAUQSLH-UHFFFAOYSA-N
SMILES: O=C1C(C2=CC(O)=C3C(C=CC(C)(C)O3)=C2)=COC4=CC(O)=CC(O)=C14
Biological Activity: Semilicoisoflavone B, an isoflavone, mainly derived from Glycyrrhiza uralensis Fisch.. Semilicoisoflavone B reduces amyloid β (Aβ) secretion by inhibiting β-secretase-1 (BACE1) expression and activity. Semilicoisoflavone B decreases BACE1 expression mainly through increasing PPARγ expression and inhibiting STAT3 phosphorylation[1].
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Semilicoisoflavone B | 99.90% | Semilicoisoflavone B, an isoflavone, mainly derived from Glycyrrhiza uralensis Fisch.. Semilicoisoflavone B reduces amyloid β (Aβ) secretion by inhibiting β-secretase-1 (BACE1) expression and activity. Semilicoisoflavone B decreases BACE1 expression mainly through increasing PPARγ expression and inhibiting STAT3 phosphorylation. | ||||||||||||||||||||
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