18 Results for "

anandamide (AEA)

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "anandamide (AEA)" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-10863
CAS No.: 94421-68-8
Purity:  ≥98.0%
Synonyms: AEA; Arachidonoyl ethanolamide
Anandamide is an endocannabinoid. Anandamide modulates both neuronal and immune functions through two protein-coupled cannabinoid receptors (CB1 and CB2). Anandamide can activate numerous other receptors like PPARS, TRPV1, and GPR18/GPR55. Anandamide also has potential anti-fungal and anti-inflammatory activities. Anandamide can be used for the research of Alzheimer’s disease (AD) and ulcerative colitis .
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1
1 Cited Publications
Cat. No.: HY-103332
CAS No.: 179113-91-8
Purity:  98.90%
Synonyms: NA-Gly
N-Arachidonylglycine (NA-Gly), a carboxylic analog of the endocannabinoid anandamide (AEA), is a GPR18 agonist (EC50 = 44.5 nM). Unlike AEA, N-Arachidonylglycine has no activity at either CB1 or CB2 receptors. N-Arachidonylglycine inhibits GLYT2 (IC50 = 5.1 μM). N-Arachidonylglycine also is an effective activator of endometrial cell migration .
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Cat. No.: HY-110072S
CAS No.: 946524-40-9
Synonyms: AEA-d4; Arachidonoyl ethanolamide-d4
Anandamide-d4 (AEA-d4) is the deuterium labeled Anandamide.
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Cat. No.: HY-N16008
CAS No.: 913692-69-0
Category:  

Lipids

C20:4 Anandamide (AEA) is a class of anandamides.
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Cat. No.: HY-10863S
CAS No.: 924894-98-4
Synonyms: AEA-d8
Anandamide-d8 is a deuterated labeled Anandamide . Anandamide is an endocannabinoid. Anandamide modulates both neuronal and immune functions through two protein-coupled cannabinoid receptors (CB1 and CB2). Anandamide can activate numerous other receptors like PPARS, TRPV1, and GPR18/GPR55. Anandamide also has potential anti-fungal and anti-inflammatory activities. Anandamide can be used for the research of Alzheimer’s disease (AD) and ulcerative colitis .
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Cat. No.: HY-118140
CAS No.: 1998197-39-9
Purity:  99.43%
ZCZ011 is a potent and brain-penetrant cannabinoid 1 (CB1) receptor positive allosteric modulator. ZCZ011 potentiates binding of CP55,940 to the CB1 receptor, enhances anandamide (AEA)-stimulated GTPγS binding in mouse brain membranes. ZCZ011 increases β-arrestin recruitment and ERK phosphorylation in hCB1 cells. ZCZ011 can be used for researching neuropathic and inflammatory pain .
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Cat. No.: HY-W127407
CAS No.: 201738-25-2
Glycerophospho-N-Arachidonoyl Ethanolamine is a N-acylated ethanolamines (NAEs). Most NAEs are naturally occurring lipids with diverse biological activities. Different types of NAE can be derived from glycerophosphate-linked precursors through the activity of glycerophosphodiesterase 1 (GDE1). Glycerophosphate-N-Arachidonoyl Ethanolamine is the precursor of Anandamide (AEA), also known as Anandamide. AEA is an endocannabinoid neurotransmitter that binds to central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. It inhibits the specific binding of [3H]-HU-243 to synaptosomal membranes with a Ki value of 52 nM compared to 46 nM for δ9-THC.
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Cat. No.: HY-10863S1
CAS No.: 2260669-86-9
Synonyms: AEA-d11
Anandamide-d11 is deuterium labeled Anandamide. Anandamide is an immune modulator in the central nervous system acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55) .
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Cat. No.: HY-103340
CAS No.: 439080-01-0
Target:  

Cannabinoid Receptor

Research Areas:  

Neurological Disease

O-2093 is a selective endocannabinoid anandamide (AEA) reuptake inhibitor with IC50 of 17.3 μM .
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Cat. No.: HY-120649
CAS No.: 290374-09-3
SKM 4-45-1 is an analog of Anandamide (AEA)(HY-10863). SKM 4-45-1 is a fluorescent substrate, that can be used to study the transmembrane carrier-mediated transport of AEA across cell membranes .
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Cat. No.: HY-10863S2
Synonyms: AEA-15NN; Arachidonoyl ethanolamide-15NN
Anandamide- 15N (AEA- 15N) is the 15N-labeled Anandamide (HY-10863). Anandamide is an endocannabinoid. Anandamide modulates both neuronal and immune functions through two protein-coupled cannabinoid receptors (CB1 and CB2). Anandamide can activate numerous other receptors like PPARS, TRPV1, and GPR18/GPR55. Anandamide also has potential anti-fungal and anti-inflammatory activities. Anandamide can be used for the research of Alzheimer’s disease (AD) and ulcerative colitis .
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Cat. No.: HY-134110
CAS No.: 156910-29-1
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Anandamide (AEA) is an endogenous cannabinoid that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. The biological actions of AEA are terminated by cellular uptake and hydrolysis of the amide bond by the enzyme fatty acid amide hydrolase. Arachidonoyl-N-methyl amide is an analog of anandamide that binds to the human central cannabinoid (CB1) receptor with a Ki of 60 nM. It inhibits rat glial gap junction cell-cell communication 100% at a concentration of 50 μM.
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Cat. No.: HY-103338
CAS No.: 251908-92-6
Target:  

Others

Research Areas:  

Neurological Disease

AM1172 is metabolically stable anandamide uptake inhibitor. AM1172 inhibits [ 3H] anandamide transport in rat cortical neurons and human CCF-STTG1 astrocytoma cells with IC50 values of 2.1 μM and 2.5 μM, respectively. AM1172 can significantly inhibit AEA hydrolysis and concurrently decrease AEA uptake. AM1172 can be used for the study of endocannabinoid system regulation .
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Cat. No.: HY-134055
CAS No.: 45280-17-9
Synonyms: Arachidonic acid-N,N-dimethyl amide
Target:  

Cannabinoid Receptor

Research Areas:  

Metabolic Disease

Anandamide (AEA) is an endogenous cannabinoid that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. The biological actions of AEA are terminated by cellular uptake and hydrolysis of the amide bond by the enzyme fatty acid amide hydrolase. Arachidonoyl-N,N-dimethyl amide is an analog of anandamide that exhibits weak or no binding to the human central cannabinoid (CB1) receptor (Ki >1 μM). It inhibits rat glial gap junction cell-cell communication 100% at a concentration of 50 μM.
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Cat. No.: HY-103332S
CAS No.: 1159908-44-7
Purity:  98.1%
Synonyms: NA-Gly-d8
N-Arachidonylglycine-d8 is a deuterated labeled N-Arachidonylglycine . N-Arachidonylglycine (NA-Gly), a carboxylic analog of the endocannabinoid anandamide (AEA), is a GPR18 agonist (EC50 = 44.5 nM). Unlike AEA, N-Arachidonylglycine has no activity at either CB1 or CB2 receptors. N-Arachidonylglycine inhibits GLYT2 (IC50 = 5.1 μM). N-Arachidonylglycine also is an effective activator of endometrial cell migration .
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Cat. No.: HY-175062
Synonyms: iPF2α-III ethanolamide; 8-Isoprostane ethanolamide; 8-iso PGF2α ethanolamide
Target:  

Drug Derivative

Research Areas:  

Others

8-isoprostaglandin F2α ethanolamide (iPF2α-III ethanolamide; 8-Isoprostane ethanolamide; 8-iso PGF2α ethanolamide) is an isoprostanol ethanolamide derivative derived from anandamide (AEA) via non-enzymatic free radical oxidation. 8-isoprostaglandin F2α ethanolamide is commonly used as a marker of oxidative stress, distinguishing non-enzymatic degradation products from "prostamides" generated by enzymatic pathways such as COX-2 .
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Cat. No.: HY-120971
CAS No.: 72298-63-6
Synonyms: DepNA
N-Decanoyl p-nitroaniline (DepNA) is one of several nitroaniline fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity.1 FAAH is a relatively unselective enzyme in that it accepts a variety of amide head groups other than the ethanolamine of its endogenous substrate anandamide (AEA). It also will hydrolyze fatty acid amides with fewer carbons and fewer double bonds than arachidonate. Exposure of DepNA to FAAH activity results in the release of the yellow colorimetric dye p-nitroaniline (ε=13,500 at 410 nm). This allows the fast and convenient measurement of FAAH activity using a 96 well plate spectrophotometer.
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Cat. No.: HY-179857
CAS No.: 2134633-42-2
Research Areas:  

Metabolic Disease

NBD AEA is a fluorescent arachidonoylethanolamide (anandamide, AEA).
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