1. GPCR/G Protein
    Neuronal Signaling
  2. Cannabinoid Receptor
  3. ZCZ011

ZCZ011 

Cat. No.: HY-118140
Handling Instructions

ZCZ011 is a potent and brain penetrant cannabinoid 1 (CB1) receptor positive allosteric modulator. ZCZ011 potentiates binding of CP55,940 to the CB1 receptor, enhances anandamide (AEA)-stimulated GTPγS binding in mouse brain membranes. ZCZ011 increases β-arrestin recruitment and ERK phosphorylation in hCB1 cells. ZCZ011 can be used for researching neuropathic and inflammatory pain.

For research use only. We do not sell to patients.

ZCZ011 Chemical Structure

ZCZ011 Chemical Structure

CAS No. : 1998197-39-9

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Description

ZCZ011 is a potent and brain penetrant cannabinoid 1 (CB1) receptor positive allosteric modulator. ZCZ011 potentiates binding of CP55,940 to the CB1 receptor, enhances anandamide (AEA)-stimulated GTPγS binding in mouse brain membranes. ZCZ011 increases β-arrestin recruitment and ERK phosphorylation in hCB1 cells. ZCZ011 can be used for researching neuropathic and inflammatory pain[1].

IC50 & Target

CB1[1]

Molecular Weight

362.44

Formula

C21H18N2O2S

CAS No.
SMILES

O=[N+](CC(C1=C(C2=CC=CC=C2)NC3=C1C=CC(C)=C3)C4=CC=CS4)[O-]

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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ZCZ011
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