19 Results for "

ansamycins

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "ansamycins" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-17025
CAS No.: 72559-06-9
Synonyms: Ansamycin; LM-427
Research Areas:  

Infection

Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.
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Cat. No.: HY-B1907
CAS No.: 14897-39-3
Synonyms: Rifamycin SV sodium
Rifamycin sodium (Rifamycin SV monosodium) is an orally active ansamycin antibiotic. Rifamycin sodium inhibits DNA-dependent RNA synthesis. Rifamycin sodium has antibacterial activity against Mycobacterium tuberculosis. Rifamycin sodium interferes with hepatic bile acid metabolism. Rifamycin sodium has anti-inflammatory effects. Rifamycin sodium can be used in the study of Mycobacterium tuberculosis, Bacteroides fragilis infection, and Lipopolysaccharide (HY-D1056B3)-induced inflammation .
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Cat. No.: HY-17025S
CAS No.: 2747918-39-2
Synonyms: Ansamycin-d7; LM-427-d7
Rifabutin-d7 is the deuterium labeled Rifabutin. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.
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Cat. No.: HY-B1907A
CAS No.: 6998-60-3
Synonyms: Rifamycin SV
Research Areas:  

Infection

Rifamycin (Rifamycin SV) is an orally active ansamycin antibiotic. Rifamycin inhibits DNA-dependent RNA synthesis. Rifamycin has antibacterial activity against Mycobacterium tuberculosis. Rifamycin interferes with hepatic bile acid metabolism. Rifamycin has anti-inflammatory effects. Rifamycin can be used in the study of Mycobacterium tuberculosis, Bacteroides fragilis infection, and Lipopolysaccharide (HY-D1056B3)-induced inflammation .
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Cat. No.: HY-W077634
CAS No.: 76045-71-1
Synonyms: AHBA
Target:  

Drug Intermediate

Research Areas:  

Infection

3-Amino-5-hydroxybenzoic acid is a biosynthetic precursor of the mC7N unit of ansamycin antibiotics, including ansatrienin A and geldanamycin, as well as the antitumor antibiotic mitomycin C. 3-Amino-5-hydroxybenzoic acid may be an early intermediate in the shikimic acid pathway from glucose .
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Cat. No.: HY-17025R
CAS No.: 72559-06-9
Synonyms: Ansamycin (Standard); LM-427 (Standard)
Research Areas:  

Infection

Rifabutin (Standard) is the analytical standard of Rifabutin. This product is intended for research and analytical applications. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.
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Cat. No.: HY-162836
CAS No.: 13929-35-6
Synonyms: 4-O-(Carboxymethyl)-Rifamycin
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Rifamycin B (4-O-(Carboxymethyl)-Rifamycin) is a member of ansamycin antibiotics family with an anti-mycobacterial activity against tuberculosis, leprosy and AIDS-related mycobacterial infections. Rifamycin B is a metabolic product of Nocardia inediterranei, which can yield Rifamycin O and Rifamycin S (HY-125365) by microbial transformation .
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Cat. No.: HY-133571
CAS No.: 485395-71-9
Purity:  99.56%
Synonyms: AHGDM
Target:  

HSP ADC Payloads

Research Areas:  

Cancer

Aminohexylgeldanamycin (AHGDM), a Geldanamycin derivative, is a potent HSP90 inhibitor. Aminohexylgeldanamycin shows antiangiogenic and antitumor activities .
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Cat. No.: HY-122306
CAS No.: 82189-04-6
Synonyms: Mycotrienin II
Target:  

Antibiotic Bacterial

Research Areas:  

Infection Cancer

Ansatrienin B (Mycotrienin II) is an ansamycin antibiotic isolated from Streptomyces. Ansatrienin B is active against fungi and yeasts, but inactive against bacteria.Ansatrienin B displays antitumor antibiotic activity and can be used as an ADC Toxin .
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Cat. No.: HY-133571A
CAS No.: 1146534-45-3
Synonyms: AHGDM hydrochloride
Target:  

HSP ADC Payloads

Research Areas:  

Cancer

Aminohexylgeldanamycin (AHGDM) hydrochloride, a Geldanamycin derivative, is a potent HSP90 inhibitor. Aminohexylgeldanamycin hydrochloride shows antiangiogenic and antitumor activities .
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Cat. No.: HY-17025S1
Synonyms: Ansamycin-d6; LM-427-d6
Rifabutin-d6 (Ansamycin-d6) is deuterium labeled Rifabutin. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.
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Cat. No.: HY-129312
CAS No.: 87913-35-7
Awamycin is an antitumor ansamycin antibiotic .
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Cat. No.: HY-N15103
CAS No.: 178550-62-4
Hydroxymycotrienin B is an ansamycin group antibiotic (triene-ansamycin) found in culture broths of Bacillus sp. BMJ958-62F4. Hydroxymycotrienin B inhibits HPV-positive cervical cancer cell growth 3~10 times more strongly than HPV-negative cervical cancer cells. Hydroxymycotrienin B can be used for the research of human cervical cancer .
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Cat. No.: HY-117180
CAS No.: 102281-52-7
Synonyms: 30-Hydroxy-naphthomycin C
Diastovaricin I (30-Hydroxy-naphthomycin C) is an antibiotic without exhibiting antimicrobial activity. Diastovaricin I induces differentation of mouse Friend cell .
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Cat. No.: HY-N15076
CAS No.: 76207-83-5
Herbimycin B is an ansamycin antibiotic that acts as a Src family kinase inhibitor. Herbimycin B has herbicidal effect on most monocotyledons and dicotyledons, inhibits the activity of tobacco Mosaic virus (TMV), HeLa cells and Ehrlich cells .
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Cat. No.: HY-178299S
CAS No.: 773801-41-5
3-Amino-5-hydroxybenzoic acid- 13C is the 13C-labeled 3-Amino-5-hydroxybenzoic acid (HY-W077634). 3-Amino-5-hydroxybenzoic acid is a biosynthetic precursor of the mC7N unit of ansamycin antibiotics, including ansatrienin A and geldanamycin, as well as the antitumor antibiotic mitomycin C. 3-Amino-5-hydroxybenzoic acid may be an early intermediate in the shikimic acid pathway from glucose .
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Cat. No.: HY-B1907R
CAS No.: 14897-39-3
Synonyms: Rifamycin SV sodium (Standard)
Rifamycin (sodium) (Standard) is the analytical standard of Rifamycin (sodium). This product is intended for research and analytical applications. Rifamycin sodium (Rifamycin SV sodium) is an orally active ansamycin antibiotic. Rifamycin sodium inhibits DNA-dependent RNA synthesis. Rifamycin sodium has antibacterial activity against Mycobacterium tuberculosis. Rifamycin sodium interferes with hepatic bile acid metabolism. Rifamycin sodium has anti-inflammatory effects. Rifamycin sodium can be used in the study of Mycobacterium tuberculosis, Bacteroides fragilis infection, and Lipopolysaccharide (HY-D1056B3)-induced inflammation .
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Cat. No.: HY-126935
CAS No.: 85819-31-4
Target:  

Others

Ansatrienin A3, also known as Mycotrienin, is a minor component of the ansamycin complex produced by Streptomyces collinus.
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Cat. No.: HY-N21816
CAS No.: 115626-67-0
OM-4842 is an ansamycin antibiotic and platelet aggregation inhibitor derived from Streptomyces. OM-4842 inhibits platelet aggregation induced by Adenosine 5'-diphosphate (ADP) (HY-W010918), Arachidonic acid (HY-109590), and C16-PAF (PAF) (HY-108635), and exerts growth-inhibitory activity against Doxorubicin (HY-15142A)-resistant P388 mouse leukemia cells. OM-4842 is used in research on platelet aggregation-related disorders and drug-resistant leukemia .
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