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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
anti-TNF
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "anti-TNF" in MCE Product Catalog:
30
30 Publications Verification
Cat. No.: HY-P9970A
Synonyms: Avakine (anti-TNF-α); CT-P13 (anti-TNF-α)
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
1
1 Cited Publications
Cat. No.: HY-P99810
CAS No.: 2427667-03-4
Synonyms: AVTX-002; AEVI 002; SAR 252067; CERC-002; MDGN-002
Target:
Research Areas:
Quisovalimab (AVTX-002) is a human-derived monoclonal antibody against LIGHT (TNFSF14). Quisovalimab binds to LIGHT, blocks the signal transduction activity of LIGHT, reduces circulating LIGHT levels and attenuates pro-inflammatory effects. Quisovalimab can be used in research related to Crohn's disease, COVID-19-associated pneumonia and acute respiratory distress syndrome comorbidity .
Target:
Research Areas:
Oxazolone is a haptenizing agent that induces acute or chronic inflammation of the large intestine and is used to construct models of colitis. Oxazolone can cause Th1/Th2-dependent colitis with weight loss and diarrhea. Oxazolone-induced inflammation can be mitigated by neutralizing anti-IL-4 or anti-TNF-α antibodies or decoy IL-13R2-α-FC proteins .
Cat. No.: HY-P99796
CAS No.: 1167985-17-2
Synonyms: ATN-103; PF-5230896
Target:
Research Areas:
Cat. No.: HY-164894
Research Areas:
ABBV-3373 is an anti-TNF antibody-drug conjugate (ADC). ABBV-3373 consists of a fully human TNF antibody Adalimumab (HY-P9908) conjugated to a glucocorticoid receptor agonist (HY-148436). ABBV-3373 can be used for the research of rheumatoid arthritis .
Cat. No.: HY-W010162
CAS No.: 1948-31-8
Synonyms: L-Alanyl-L-alanine; Ala-Ala
Cat. No.: HY-P99704
CAS No.: 1688648-13-6
Synonyms: OCS-02
Target:
Research Areas:
Cat. No.: HY-164893
Cat. No.: HY-P99775
CAS No.: 945781-29-3
Synonyms: ART621; CEP-37247; PN0621
Target:
Research Areas:
Cat. No.: HY-P99753
CAS No.: 162774-06-3
Synonyms: BAYX1351
Target:
Research Areas:
Cat. No.: HY-161381
CAS No.: 3034837-89-0
Target:
Research Areas:
PDE4-IN-15 (compound 7b-1) is an inhibitor of PDE4 (IC50 = 0.17 μM) and has anti-TNF-α activity (EC50 = 0.19 μM). PDE4-IN-15 has a good skin permeability .
Cat. No.: HY-124388
CAS No.: 1396397-03-7
Target:
Research Areas:
PDE4-IN-20 is a selective submicromolar phosphodiesterase-4 (PDE4) inhibitor with anti-TNF-α properties. PDE4-IN-20 exhibits significant biological activity in vitro and in vivo. The mechanism of action of PDE4-IN-20 is supported by molecular modeling studies, which reveal its binding mode with PDE4. PDE4-IN-20 was optimized in further conformational analysis and showed pharmacological characteristics similar to those of known PDE4 inhibitors .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
