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Results for "

aspergillosis

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100373
    Isavuconazonium sulfate
    3 Publications Verification

    BAL8557-002

    		 Fungal Infection
    Isavuconazonium sulfate (BAL8557-002) is an orally active broad-spectrum antifungal molecule. Isavuconazonium sulfate is a precursor of the triazole antifungal active molecule Isavuconazole. Isavuconazonium sulfate can be used in the study of invasive aspergillosis, mucormycosis, blastomycosis, and Acanthamoeba keratitis .
    Isavuconazonium sulfate
  • HY-W587956
    α-Guaiene

    		Fungal Infection
    α-Guaiene is a natural sesquiterpene and fungicidal agent found in Pogostemon cablin (patchouli) essential oil. α-Guaiene suppresses the growth of Aspergillus niger, Candida albicans, Microsporum gypseum, and Trichophyton mentagrophytes. α-Guaiene can be used for the study of fungal infection .
    α-Guaiene
  • HY-N9710
    Bis(methylthio)gliotoxin

    Bisdethiobis(methylthio)gliotoxin; FR 49175; Dimethylgliotoxin

    		 Fungal Infection
    Bis(methylthio)gliotoxin is a more stable and reliable marker for invasive aspergillosis than gliotoxin and suitable for use in diagnosis .
    Bis(methylthio)gliotoxin
  • HY-106333
    Irtemazole

    R 60844

    		 Fungal Infection Inflammation/Immunology
    Irtemazole is an orally active antifungal agent. Irtemazole possesses uricosuric effect. Irtemazole is used in the research for blastomycosis, histoplasmosis, and aspergillosis .
    Irtemazole
  • HY-114219
    Oleylphosphocholine

    		Fungal Parasite Infection
    Oleylphosphocholine is an orally active antifungal and antiparasitic agent. Oleylphosphocholine is promising for research of invasive fungal diseases (e.g., aspergillosis) and visceral leishmaniasis .
    Oleylphosphocholine
  • HY-105110
    SCH 39304

    SM-8668

    		 Fungal Infection
    SM-8668 is an effective orally active antifungal agent, with median effective doses (ED50) of 0.18, 3.7, and 5.9 mg/kg for systemic candidiasis, aspergillosis, and cryptococcosis in mice, respectively. Pharmacokinetic studies in mice and rats indicate that SM-8668 has a long half-life and a high total exposure. SM-8668 can be used in anti-infective research .
    SCH 39304
  • HY-100373R
    Isavuconazonium sulfate (Standard)

    BAL8557-002 (Standard)

    		 Fungal Reference Standards Infection
    Isavuconazonium (sulfate) (Standard) is the analytical standard of Isavuconazonium (sulfate) (HY-100373). This product is intended for research and analytical applications. Isavuconazonium sulfate (BAL8557-002) is an orally active broad-spectrum antifungal molecule. Isavuconazonium sulfate is a precursor of the triazole antifungal active molecule Isavuconazole. Isavuconazonium sulfate can be used in the study of invasive aspergillosis, mucormycosis, blastomycosis, and Acanthamoeba keratitis .
    Isavuconazonium sulfate (Standard)
  • HY-119726B
    Fosmanogepix TFA

    		Fungal Infection
    Fosmanogepix TFA (APX001 TFA) is an orally active APX001A (HY-18233) prodrug and antifungal agent. Fosmanogepix TFA is effective against Cryptococcus neoformans, Fluconazole (HY-B0101)-resistant C. auris. Fosmanogepix TFA is effective in the treatment of invasive pulmonary aspergillosis and pulmonary murine mucormycosis .
    Fosmanogepix TFA
  • HY-109125
    SPK-843

    SPA-S-753 free base

    		 Fungal Infection
    SPK-843 is an antifungal agent. SPK-843 shows inhibitory activity against A. fumigatus MF-13, A. flavus TIMM 0057, and A. niger TIMM 2814 with MICs of 0.5 μg/mL, 0.25 μg/mL, and 0.0625 μg/mL, respectively. SPK-843 exhibits dose-dependent efficacy in murine models of pulmonary aspergillosis. SPK-843 can be used for the research of related fungal infections .
    SPK-843
  • HY-125459
    L 705589

    		Fungal Infection
    L-705589 is a semi-synthetic penicillin-type antifungal agent. L-705589 exerts its antifungal effect by inhibiting the 1,3-β-D-glucan synthase in the fungal cell wall. L-705589 exhibits potent bactericidal activity against various Candida species (such as Candida albicans, Candida glabrata, Candida krusei, etc.) (MFC: 0.06 - 8 μg/mL), but has relatively weak activity against Cryptococcus neoformans (MFC: 32 - 64 μg/mL). L-705589 remains active against drug-resistant Candida strains and is not prone to inducing drug resistance. L-705589 significantly improves survival rates in the model of minor invasive aspergillosis .
    L 705589

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