257925-44-3
257925-44-3
Chemical Structure
Oleylphosphocholine
- CAS No.: 257925-44-3
- Formula:C23H48NO4P
- Molecular Weight:433.61
IUPAC Name: (Z)-octadec-8-en-1-yl (2-(trimethylammonio)ethyl) phosphate
InChIKey: HVFNJWAGZROLBS-YPKPFQOOSA-N
SMILES: CCCCCCCCC/C=C\CCCCCCCOP([O-])(OCC[N+](C)(C)C)=O
Biological Activity: Oleylphosphocholine is an orally active antifungal and antiparasitic agent. Oleylphosphocholine is promising for research of invasive fungal diseases (e.g., aspergillosis) and visceral leishmaniasis[1][2].
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Oleylphosphocholine | Oleylphosphocholine is an orally active antifungal and antiparasitic agent. Oleylphosphocholine is promising for research of invasive fungal diseases (e.g., aspergillosis) and visceral leishmaniasis. | |||||||||||||||||||||
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References
- [1]. Dawson R, et al. Phase I Single Ascending Dose and Food Effect Study in Healthy Adults and Phase I/IIa Multiple Ascending Dose Study in Patients with Pulmonary Tuberculosis to Assess Pharmacokinetics, Bactericidal Activity, Tolerability, and Safety of OPC-167832. Antimicrob Agents Chemother. 2023 Jun 15;67(6):e0147722. [Content Brief]
- [2]. Paulussen C, et al. Efficacy of oleylphosphocholine (OlPC) in vitro and in a mouse model of invasive aspergillosis. Mycoses. 2015 Mar;58(3):127-32. [Content Brief]
