120924-80-3
Chemical Structure
SCH 39304
Synonym(s): SM-8668
- CAS No.: 120924-80-3
- Formula:C13H15F2N3O3S
- Molecular Weight:331.34
IUPAC Name: (2S,3S)-2-(2,4-difluorophenyl)-3-(methylsulfonyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
InChIKey: HFGZFHCWKKQGIS-ZANVPECISA-N
SMILES: CS([C@@H](C)[C@](O)(C1=C(C=C(C=C1)F)F)CN2C=NC=N2)(=O)=O
Biological Activity: SM-8668 is an effective orally active antifungal agent, with median effective doses (ED50) of 0.18, 3.7, and 5.9 mg/kg for systemic candidiasis, aspergillosis, and cryptococcosis in mice, respectively. Pharmacokinetic studies in mice and rats indicate that SM-8668 has a long half-life and a high total exposure. SM-8668 can be used in anti-infective research[1].
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SCH 39304 | SM-8668 is an effective orally active antifungal agent, with median effective doses (ED50) of 0.18, 3.7, and 5.9 mg/kg for systemic candidiasis, aspergillosis, and cryptococcosis in mice, respectively. Pharmacokinetic studies in mice and rats indicate that SM-8668 has a long half-life and a high total exposure. SM-8668 can be used in anti-infective research. | |||||||||||||||||||||
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Keywords
