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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
at 007 galactosemia
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "at 007 galactosemia" in MCE Product Catalog:
Synonyms: at-007
Target:
Domaines de recherche:
Govorestat (AT-007) is an orally active brain-penetrant aldose reductase inhibitor with an IC50 value of 100 pM. Govorestat has the potential for galactose-1-phosphate uridyl transferase deficiency research .
Target:
Cat. No.: HY-113043
CAS No.: 13382-27-9
Target:
Target:
Cat. No.: HY-173642
CAS No.: 2768230-55-1
Target:
Domaines de recherche:
NCGC00238624 is a selective galactokinase (GALK1) inhibitor with IC50s of 7.69 μM and 13.67 μM against the human and mouse recombinant GALK1, respectively. NCGC00238624 is inactive against GALK2 and other kinases at 10 μM. NCGC00238624 can be used for the study of classic galactosemia .
Category:
Human Gut Microbiota Metabolites Microorganisms Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides
Target:
Target:
Domaines de recherche:
Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of galactose to glucose. Galactose-1-phosphate uridylyltransferase absence results in classic galactosemia in humans and can be used for metabolic disease research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
