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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
carboxylesterase 1 (CES1)
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "carboxylesterase 1 (CES1)" in MCE Product Catalog:
Target:
Carboxylesterase (CES) Free Fatty Acid Receptor Reactive Oxygen Species (ROS) Mitochondrial Metabolism Ferroptosis Apoptosis
Research Areas:
GR148672X is an inhibitor of carboxylesterase 1 (CES1) and hepatic microsomal triglyceride hydrolase (TGH). GR148672X blocks the catalytic activity of CES1, impairs the functions of triglyceride and cholesteryl ester lipase, reduces triglyceride mobilization and secretion, and decreases apolipoprotein B-100 secretion in primary rat hepatocytes. Under low-glucose conditions, GR148672X inhibits the survival of colorectal cancer cells by reducing free fatty acid availability, inducing toxic triglyceride accumulation, ROS production, mitochondrial damage, ferroptosis and apoptosis. GR148672X can be used in studies related to colorectal cancer and atherosclerosis .
Cat. No.: HY-147331
CAS No.: 208720-71-2
Target:
Research Areas:
Oseltamivir acid methyl ester is a precursor form of the neuraminidase inhibitor and antiviral oseltamivir acid. Oseltamivir acid methyl ester is converted to oseltamivir acid by carboxylesterase 1 (CES1) .
Cat. No.: HY-P7730
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CES1; Cocaine carboxylesterase; carboxylesterase 1; Retinyl Ester Hydrolase; HMSE; Serine Esterase 1; CES2; CES1A1; SES1; CES1A2; CEH; Egasyn; HMSE1; HCE-1; carboxylesterase 1 (Monocyte/Macrophage Serine Esterase 1); ACAT; Human Monocyte/Macrophage Serine
Species:
Human
Source:
HEK293
Cat. No.: HY-P703886
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CES1; Cocaine carboxylesterase; carboxylesterase 1; Retinyl Ester Hydrolase; HMSE; Serine Esterase 1; CES2; CES1A1; SES1; CES1A2; CEH; Egasyn; HMSE1; HCE-1; carboxylesterase 1 (Monocyte/Macrophage Serine Esterase 1); ACAT; Human Monocyte/Macrophage Serine
Species:
Human
Source:
HEK293
Cat. No.: HY-147331A
CAS No.: 208720-78-9
Target:
Research Areas:
Oseltamivir acid methyl ester hydrochloride is a precursor form of the neuraminidase inhibitor and antiviral oseltamivir acid. Oseltamivir acid methyl ester hydrochloride is converted to oseltamivir acid by carboxylesterase 1 (CES1) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
