34 Results for "

collagen-induced platelet aggregation

" in MedChemExpress (MCE) Product Catalog:
Products (34)

34 Results for "collagen-induced platelet aggregation" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P99644
CAS No.: 2101829-58-5

Target:  

Glycoprotein VI

Research Areas:  

Cardiovascular Disease

ACT017 is a Fab fragment of humanized anti-GPVI monoclonal antibody. ACT017 inhibits collagen-induced platelet aggregation. ACT017 has the potential for the research of acute ischemic stroke .
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2
2 Cited Publications
Cat. No.: HY-144390
CAS No.: 1327156-14-8
Purity:  99.78%
Synonyms: GPVI antagonist 1
Target:  

Glycoprotein VI

Research Areas:  

Cardiovascular Disease

(S)-S007-1558 (compound 5) is a glycoprotein VI (GPVI) platelet receptor antagonist. (S)-S007-1558 inhibits collagen-induced platelet aggregation with an IC50 of 25.3 μM .
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1
1 Cited Publications
Cat. No.: HY-N1887
CAS No.: 1126-61-0
Synonyms: Hydroxychavicol; 4-Allylpyrocatechol
4-Allylcatechol (4-Allylpyrocatechol) is a xylan which has oral activity and can be isolated from the root of Piper taiwanense. 4-Allylcatechol has a strong inhibitory activity against collagen-induced platelet aggregation (IC50 = 5.3 μM). In addition, 4-Allylcatechol has anti-tuberculosis activity against Mycobacterium tuberculosis H37Rv (MIC = 27.6 μg/mL) .
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1
1 Cited Publications
Cat. No.: HY-18775
CAS No.: 110505-75-4
Synonyms: Para-topolin riboside
N6-(4-Hydroxybenzyl) adenosine (Para-topolin riboside) is an equilibrative nucleoside transporter 1 (ENT1) inhibitor and a selective agonist of adenosine A2a receptor (A2aR), and also exhibits activity against P2Y12 receptor. N6-(4-Hydroxybenzyl) adenosine reduces ethanol intake and preference, attenuates operant conditioning-induced ethanol place preference, decreases the value of ethanol-related rewards, and inhibits collagen-induced platelet aggregation. N6-(4-Hydroxybenzyl) adenosine can be used in studies related to alcohol use disorder .
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Cat. No.: HY-N2163
CAS No.: 172760-03-1
Mudanpioside C is a protein disulfide isomerase (PDI) inhibitor with a human IC50 of 3.31 μM and human Kd of 3.9 μM. Mudanpioside C suppresses collagen-induced platelet aggregation, interferes with platelet activation, adhesion, and spreading. Mudanpioside C can be used for the research of cardiovascular diseases .
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Cat. No.: HY-15798
CAS No.: 1493764-08-1
Purity:  99.79%
Target:  

VSV TAM Receptor

Research Areas:  

Cardiovascular Disease

UNC2881 is an orally active and specific Mer kinase inhibitor, inhibits steady-state Mer kinase phosphorylation with an IC50 value of 22 nM. UNC2881 shows additional inhibition against Axl and Tyro with IC50s of 360 nM and 250 nM, respectively. UNC2881 potently inhibits collagen-induced platelet aggregation, can be used for pathologic thrombosis research .
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Cat. No.: HY-N7619
CAS No.: 518-83-2
Synonyms: Purpuroxanthin
Xanthopurpurin is an orally active anthraquinone glycoside. Xanthopurpurin can be isolated from the rhizome of Rubia akane. Xanthopurpurin has antiviral effects against rotavirus and HIV. Xanthopurpurin has a strong inhibitory effect on collagen-induced platelet aggregation. Xanthopurpurin prevents peanut allergy .
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Cat. No.: HY-N2600
CAS No.: 76472-87-2
Kuwanon H is a selective non-peptide bombesin receptor antagonist and platelet activation inhibitor. Kuwanon H also acts as a specific antagonist of GRP-preferring receptors, with a Ki value of 290 nM for mouse GRP-R and 6500 nM for rat NMB-R. Kuwanon H inhibits the phosphorylation of AKT, mTOR, ERK, cPLA2 and p38, and upregulates TRIB3. It induces endoplasmic reticulum stress, apoptosis and autophagosome formation. Kuwanon H blocks calcium mobilization, mitogenic signaling, DNA synthesis, dense granule secretion, thromboxane A2 generation and integrin αIIb/β3 activity. It inhibits collagen-induced platelet aggregation and fibronectin adhesion, and delays clot retraction. Kuwanon H inhibits melanoma cell growth in vitro and in vivo, and enhances the sensitivity of melanoma cells to CDDP. It can be used in research related to melanoma, small cell lung cancer and thrombosis .
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Cat. No.: HY-147319
CAS No.: 825658-63-7
Purity:  99.85%
RTI-7470-44 is an orally active and blood-brain barrier-permeable antagonist of trace amine-associated receptor 1 (hTAAR1) with a Ki of 0.3 nM. RTI-7470-44 inhibits hTAAR1-mediated cAMP production and signal transduction (IC50 = 8.4 nM), and blocks hTAAR1-mediated GIRK current responses. RTI-7470-44 increases the spontaneous firing frequency of dopaminergic neurons and reduces collagen-induced platelet aggregation. RTI-7470-44 can be used in studies related to Parkinson's disease and gastric emptying .
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Cat. No.: HY-N3228
CAS No.: 89786-84-5
Myrianthic acid is a pentacyclic triterpenoid compound. Myrianthic acid can exist in the root wood of Myrianthus arboreus and the leaves of Campsis grandiflora. Myrianthic acid inhibits adrenaline-induced platelet aggregation, with a IC50 of 46.2 μM for this activity. Myrianthic acid can be used in studies related to thrombosis .
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Cat. No.: HY-P10184
CAS No.: 143257-75-4
Research Areas:  

Inflammation/Immunology

CD36 Peptide P (93-110), Cys conjugated is a Cys labelled CD36 Peptide, and can block binding of CD36 to immobilized thrombospondin and partially inhibited collagen-induced platelet aggregation .
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Cat. No.: HY-119735
CAS No.: 17015-43-9
Target:  

Others

Research Areas:  

Cardiovascular Disease

Curcolone is a sesquiterpenoid that inhibits collagen-induced or arachidonic acid (AA)-induced platelet aggregation .
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Cat. No.: HY-N3668
CAS No.: 62596-34-3
Synonyms: Cyclomorusin A; Cyclomulberrochromene
Cyclomorusin (Cyclomorusin A; Cyclomulberrochromene) is a prenylflavonoid with antiplatelet activity. Cyclomorusin also inhibits markedly collagen-induced platelet aggregation .
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Cat. No.: HY-N12514
CAS No.: 19275-51-5
Cyclomulberrin is a extended flavonoid that shows inhibition of arachidonic acid (AA)- and collagen-induced platelet aggregation, with IC50 value of 128.2 μM .
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Cat. No.: HY-119238
CAS No.: 256385-24-7
Target:  

P-glycoprotein

Research Areas:  

Cardiovascular Disease

CRL-42872 is an orally active, highly bioavailable Gp IIb/IIIa platelet receptor inhibitor. CRL-42872 inhibits the binding of fibrinogen to the Gp IIb/IIIa receptor, thereby suppressing collagen-induced platelet aggregation. CRL-42872 is widely used in thrombosis-related studies .
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Cat. No.: HY-135568
CAS No.: 256344-23-7
Target:  

P-glycoprotein

Research Areas:  

Cardiovascular Disease

CRL-42872 free base is an orally active, highly bioavailable Gp IIb/IIIa platelet receptor inhibitor. CRL-42872 free base inhibits the binding of fibrinogen to the Gp IIb/IIIa receptor, thereby suppressing collagen-induced platelet aggregation. CRL-42872 free base is widely used in thrombosis-related studies .
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Cat. No.: HY-N7316
CAS No.: 14101-04-3
Frangulin B, a natural compound that can be isolated from Rhamnus formosana, is an antagonist of collagen-induced platelet aggregation and adhesion .
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Cat. No.: HY-162375
CAS No.: 832685-79-7
Target:  

Drug Intermediate

Research Areas:  

Cardiovascular Disease

AF299 can reduce collagen-related peptide-induced platelet Ca 2+ rises and collagen-induced platelet aggregation. AF299 can be used for research of antiplatelet research .
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Cat. No.: HY-105872
CAS No.: 84203-09-8
Purity:  99.35%
Target:  

COX

Research Areas:  

Cardiovascular Disease

Trifenagrel is an orally active platelet aggregation inhibitor that inhibits the inducing effects of arachidonic acid (AA) and collagen. The ED50s of trifenagrel for inhibiting AA- and collagen-induced platelet aggregation in guinea pigs were 1.4 mg/kg and 9.4 mg/kg, respectively .
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Cat. No.: HY-N1861
CAS No.: 1486-69-7
Synonyms: Quercetin 3-O-methyl ether peracetate
3-O-Methylquercetin tetraacetate is an antiplatelet agent. 3-O-Methylquercetin tetraacetate has potent antiplatelet effect on arachidonic acid, collagen-induced and PAF-induced platelet aggregation .
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