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Cat. No.: HY-N7316

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Frangulin B

Frangulin B, a natural compound that can be isolated from Rhamnus formosana, is an antagonist of collagen-induced platelet aggregation and adhesion.

For research use only. We do not sell to patients.

CAS No.: 14101-04-3
Formula: C₂₀H₁₈O₉
Molecular Weight:402.35

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Data Sheet (267 KB)

Frangulin B Chemical Structure

CAS No.: 14101-04-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Frangulin B, a natural compound that can be isolated from Rhamnus formosana, is an antagonist of collagen-induced platelet aggregation and adhesion^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HL-60	IC₅₀	15.7 μM Compound: 2	Cytotoxicity against human HL60 cells after 72 hrs by MTT assay Cytotoxicity against human HL60 cells after 72 hrs by MTT assay	[PMID: 20561793]
KB	ED₅₀	2.49 μg/mL Compound: 6	Cytotoxicity against human KB cells Cytotoxicity against human KB cells	10.1021/np50085a021
KB	IC₅₀	2.1 μM Compound: 2	Cytotoxicity against human KB cells after 72 hrs by MTT assay Cytotoxicity against human KB cells after 72 hrs by MTT assay	[PMID: 20561793]
MDA-MB-231	IC₅₀	>20 μM Compound: 2	Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay	[PMID: 20561793]
PLC-PRF-5	ED₅₀	0.8 μg/mL Compound: 6	Cytotoxicity against human PLC/PRF/5 cells Cytotoxicity against human PLC/PRF/5 cells	10.1021/np50085a021

Chemical Information

CAS No. 14101-04-3
Appearance Solid
Molecular Weight 402.35
Formula C₂₀H₁₈O₉
Color White to off-white
SMILES

OC1=C2C(C(C(C=C(C)C=C3O)=C3C2=O)=O)=CC(O[C@@H]4OC[C@](O)(CO)[C@H]4O)=C1
Structure Classification
- Quinones
- Anthraquinones
Initial Source
- Plants
- Rhamnaceae
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. C M Teng, et al. Frangulin B, an antagonist of collagen-induced platelet aggregation and adhesion, isolated from Rhamnus formosana. Thromb Haemost. 1993 Dec 20;70(6):1014-8. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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