Frangulin B
Based on 1 Customer Validation
Frangulin B, a natural compound that can be isolated from Rhamnus formosana, is an antagonist of collagen-induced platelet aggregation and adhesion.
For research use only. We do not sell to patients.
- CAS No.: 14101-04-3
- Formula: C20H18O9
- Molecular Weight:402.35
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
15.7 μM
Compound: 2
|
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
|
[PMID: 20561793] |
| KB | ED50 |
2.49 μg/mL
Compound: 6
|
Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
|
10.1021/np50085a021 |
| KB | IC50 |
2.1 μM
Compound: 2
|
Cytotoxicity against human KB cells after 72 hrs by MTT assay
Cytotoxicity against human KB cells after 72 hrs by MTT assay
|
[PMID: 20561793] |
| MDA-MB-231 | IC50 |
>20 μM
Compound: 2
|
Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay
|
[PMID: 20561793] |
| PLC-PRF-5 | ED50 |
0.8 μg/mL
Compound: 6
|
Cytotoxicity against human PLC/PRF/5 cells
Cytotoxicity against human PLC/PRF/5 cells
|
10.1021/np50085a021 |
Chemical Information
-
CAS No. 14101-04-3
-
Molecular Weight 402.35
-
Formula C20H18O9
-
SMILES
OC1=C2C(C(C(C=C(C)C=C3O)=C3C2=O)=O)=CC(O[C@@H]4OC[C@](O)(CO)[C@H]4O)=C1
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)