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  6. Myrianthic acid

Myrianthic acid is a pentacyclic triterpenoid compound. Myrianthic acid can exist in the root wood of Myrianthus arboreus and the leaves of Campsis grandiflora. Myrianthic acid inhibits adrenaline-induced platelet aggregation, with a IC50 of 46.2 μM for this activity. Myrianthic acid can be used in studies related to thrombosis.

For research use only. We do not sell to patients.

Myrianthic acid

Myrianthic acid Chemical Structure

CAS No. : 89786-84-5

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Based on 1 publication(s) in Google Scholar

Myrianthic acid Related Antibodies

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Description

Myrianthic acid is a pentacyclic triterpenoid compound. Myrianthic acid can exist in the root wood of Myrianthus arboreus and the leaves of Campsis grandiflora. Myrianthic acid inhibits adrenaline-induced platelet aggregation, with a IC50 of 46.2 μM for this activity. Myrianthic acid can be used in studies related to thrombosis[1][2].

Cellular Effect
Cell Line Type Value Description References
HEK293 IC50
23.2 μM
Compound: 12
Inhibition of LPS-induced NF-kappaB activation in HEK293 cells incubated for 4 hrs prior to LPS challenge measured after 48 hrs by luciferase reporter gene assay
Inhibition of LPS-induced NF-kappaB activation in HEK293 cells incubated for 4 hrs prior to LPS challenge measured after 48 hrs by luciferase reporter gene assay
[PMID: 23632365]
RAW264.7 IC50
10.38 μM
Compound: 12
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-10 release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-10 release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
[PMID: 23632365]
RAW264.7 IC50
14.32 μM
Compound: 12
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced TNF-alpha release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced TNF-alpha release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
[PMID: 23632365]
RAW264.7 IC50
8.04 μM
Compound: 12
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-6 release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-6 release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
[PMID: 23632365]
RAW264.7 IC50
8.53 μM
Compound: 12
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-1beta release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-1beta release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
[PMID: 23632365]
In Vitro

Myrianthic acid inhibits adrenaline-induced platelet aggregation, with an IC50 of 46.2 μM for this activity[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Myrianthic acid Related Antibodies
Molecular Weight

504.70

Formula

C30H48O6
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC([C@]12[C@]([C@](O)([C@@H](CC2)C)C)([H])C3=CC[C@@]([C@@]4([C@@]([C@@](C)([C@@H]([C@@H](C4)O)O)CO)([H])CC5)C)([H])[C@]5(C)[C@@]3(CC1)C)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation
References
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Myrianthic acid Related Classifications

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  • Dilution Calculator

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Myrianthic acid89786-84-5Othersepinephrine-induced platelet aggregationpentacyclic triterpene acidthrombosisCampsis grandifloracollagen-induced platelet aggregationarachidonic acid-induced platelet aggregationrat platelet-rich plasmaADP-induced platelet aggregationU46619-induced platelet aggregationMyrianthus arboreusInhibitorinhibitorinhibit

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