Myrianthic acid
Based on 1 Customer Validation
Myrianthic acid is a pentacyclic triterpenoid compound. Myrianthic acid can exist in the root wood of Myrianthus arboreus and the leaves of Campsis grandiflora. Myrianthic acid inhibits adrenaline-induced platelet aggregation, with a IC50 of 46.2 μM for this activity. Myrianthic acid can be used in studies related to thrombosis.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 89786-84-5
- Formula: C30H48O6
- Molecular Weight:504.70
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| RAW264.7 | IC50 |
10.38 μM
Compound: 12
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-10 release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-10 release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
|
[PMID: 23632365] |
| RAW264.7 | IC50 |
14.32 μM
Compound: 12
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Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced TNF-alpha release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced TNF-alpha release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
|
[PMID: 23632365] |
| RAW264.7 | IC50 |
8.04 μM
Compound: 12
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Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-6 release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-6 release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
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[PMID: 23632365] |
| RAW264.7 | IC50 |
8.53 μM
Compound: 12
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Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-1beta release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-1beta release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
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[PMID: 23632365] |
In Vitro
Myrianthic acid inhibits adrenaline-induced platelet aggregation, with an IC50 of 46.2 μM for this activity[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 89786-84-5
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Appearance Solid
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Molecular Weight 504.70
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Formula C30H48O6
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Color White to off-white
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SMILES
OC([C@]12[C@]([C@](O)([C@@H](CC2)C)C)([H])C3=CC[C@@]([C@@]4([C@@]([C@@](C)([C@@H]([C@@H](C4)O)O)CO)([H])CC5)C)([H])[C@]5(C)[C@@]3(CC1)C)=O
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Myrianthic acid Related Classifications
HY-N3228 Related Classifications
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Keywords
- Myrianthic acid
- 89786-84-5
- Others
- epinephrine-induced platelet aggregation
- pentacyclic triterpene acid
- thrombosis
- Campsis grandiflora
- collagen-induced platelet aggregation
- arachidonic acid-induced platelet aggregation
- rat platelet-rich plasma
- ADP-induced platelet aggregation
- U46619-induced platelet aggregation
- Myrianthus arboreus
- Inhibitor
- inhibitor
- inhibit