(S)-S007-1558
Based on 2 publication(s) in Google Scholar
(S)-S007-1558 (compound 5) is a glycoprotein VI (GPVI) platelet receptor antagonist. (S)-S007-1558 inhibits collagen-induced platelet aggregation with an IC50 of 25.3 μM.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.78%
- CAS. Nr.: 1327156-14-8
- Formel: C19H19N3O4S
- Molecular Weight:385.44
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) (S)-S007-1558
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Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 1327156-14-8
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Appearance Solid
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Molecular Weight 385.44
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Formel C19H19N3O4S
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Color White to off-white
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SMILES
O=C([C@@H]1CC2=C(CN1S(=O)(C3=CC=C(OC)C=C3)=O)NC4=C2C=CC=C4)N
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Synonyms
GPVI antagonist 1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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Int J Biol Macromol
Sibanin, a novel black fly-derived Kunitz protease inhibitor, prevents thrombus formation in mice by anticoagulation-antiplatelet duality. [Abstract]2025 Mar:296:139766. PMID: 39800030 -
Mol Immunol
HSP47 inhibitor Col003 attenuates thromboinflammation after cerebral ischemia-reperfusion by suppressing GPVI-mediated CD84 shedding in platelets. [Abstract]2026 Jul:195:186-197. PMID: 42172863
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : ≥ 50 mg/mL (129.72 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5944 mL | 12.9722 mL | 25.9444 mL | 64.8609 mL |
| 5 mM | 0.5189 mL | 2.5944 mL | 5.1889 mL | 12.9722 mL | |
| 10 mM | 0.2594 mL | 1.2972 mL | 2.5944 mL | 6.4861 mL | |
| 15 mM | 0.1730 mL | 0.8648 mL | 1.7296 mL | 4.3241 mL | |
| 20 mM | 0.1297 mL | 0.6486 mL | 1.2972 mL | 3.2430 mL | |
| 25 mM | 0.1038 mL | 0.5189 mL | 1.0378 mL | 2.5944 mL | |
| 30 mM | 0.0865 mL | 0.4324 mL | 0.8648 mL | 2.1620 mL | |
| 40 mM | 0.0649 mL | 0.3243 mL | 0.6486 mL | 1.6215 mL | |
| 50 mM | 0.0519 mL | 0.2594 mL | 0.5189 mL | 1.2972 mL | |
| 60 mM | 0.0432 mL | 0.2162 mL | 0.4324 mL | 1.0810 mL | |
| 80 mM | 0.0324 mL | 0.1622 mL | 0.3243 mL | 0.8108 mL | |
| 100 mM | 0.0259 mL | 0.1297 mL | 0.2594 mL | 0.6486 mL |
(S)-S007-1558 Related Classifications
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