130 Results for "

crystal

" in MedChemExpress (MCE) Product Catalog:
Products (130)

130 Results for "crystal" in MCE Product Catalog:

69
69 Publications Verification
Cat. No.: HY-B0324A
CAS No.: 548-62-9
Synonyms: Basic Violet 3; Gentian Violet; Methyl Violet 10B
Crystal Violet, also known as Gentian violet, methyl violet 10B, is a triphenyl-methane, an alkaline dye that binds to DNA in the nucleus of a cell, staining it a deep purple. It is often used for Gram staining to classify bacteria, or for cell or histological staining[1].
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22
22 Cited Publications
Cat. No.: HY-W099571
CAS No.: 4485-12-5
Synonyms: Stearic acid lithium; Lithium octadecanoate
Lithium stearate (Stearic acid (lithium)) is a compound that forms vesicles in reaction with silver nitrate, thereby changing the reaction kinetics of the nucleation and self-assembly process of silver stearate. It has the activity that even in the presence of excess silver nitrate, only about 80% can be converted into silver stearate and the residual lithium stearate will inhibit the growth process of silver stearate crystals, thereby producing silver stearate crystals that are much smaller than those obtained from sodium stearate, providing an opportunity to further control the self-assembly and crystal growth of silver stearate.
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5
5 Cited Publications
Cat. No.: HY-N0666
CAS No.: 56-84-8
L-Aspartic acid is a NMDA receptor agonist and acidic amino acid. L-Aspartic acid has no independent analgesic activity. L-Aspartic acid can antagonize the analgesic effects of D-Aspartic acid and Morphine. L-Aspartic acid regulates polymorph transformation, crystal growth/aggregation and nucleation processes of calcium carbonate, and can serve as a biomineralization template. L-Aspartic acid promotes burst firing of central neurons. L-Aspartic acid can be used in studies related to cerebral ischemia and epilepsy .
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5
5 Cited Publications
Cat. No.: HY-N0666A
CAS No.: 1115-63-5
L-Aspartic acid potassium (potassium L-aspartate) is a NMDA receptor agonist and acidic amino acid. L-Aspartic acid potassium has no independent analgesic activity. L-Aspartic acid potassium can antagonize the analgesic effects of D-Aspartic acid and Morphine. L-Aspartic acid potassium regulates polymorph transformation, crystal growth/aggregation and nucleation processes of calcium carbonate, and can serve as a biomineralization template. L-Aspartic acid potassium promotes burst firing of central neurons. L-Aspartic acid potassium can be used in studies related to cerebral ischemia and epilepsy .
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5
5 Cited Publications
Cat. No.: HY-N0666B
CAS No.: 10389-09-0
Synonyms: Calcium L-aspartate
Aspartic acid calcium (calcium L-aspartate) is a NMDA receptor agonist and acidic amino acid. Aspartic acid calcium has no independent analgesic activity. Aspartic acid calcium can antagonize the analgesic effects of D-Aspartic acid and Morphine. Aspartic acid calcium regulates polymorph transformation, crystal growth/aggregation and nucleation processes of calcium carbonate, and can serve as a biomineralization template. Aspartic acid calcium promotes burst firing of central neurons. Aspartic acid calcium can be used in studies related to cerebral ischemia and epilepsy .
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5
5 Cited Publications
Cat. No.: HY-N0666C
CAS No.: 3792-50-5
Synonyms: Sodium L-aspartate
L-Aspartic acid sodium (Sodium L-aspartate) is a NMDA receptor agonist and acidic amino acid. L-Aspartic acid sodium has no independent analgesic activity. L-Aspartic acid sodium can antagonize the analgesic effects of D-Aspartic acid and Morphine. L-Aspartic acid sodium regulates polymorph transformation, crystal growth/aggregation and nucleation processes of calcium carbonate, and can serve as a biomineralization template. L-Aspartic acid sodium promotes burst firing of central neurons. L-Aspartic acid sodium can be used in studies related to cerebral ischemia and epilepsy .
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5
5 Cited Publications
Cat. No.: HY-N0666D
CAS No.: 5598-53-8
Synonyms: Disodium L-aspartate
L-Aspartic acid disodium (disodium L-aspartate) is a NMDA receptor agonist and acidic amino acid. L-Aspartic acid disodium has no independent analgesic activity. L-Aspartic acid disodium can antagonize the analgesic effects of D-Aspartic acid and Morphine. L-Aspartic acid disodium regulates polymorph transformation, crystal growth/aggregation and nucleation processes of calcium carbonate, and can serve as a biomineralization template. L-Aspartic acid disodium promotes burst firing of central neurons. L-Aspartic acid disodium can be used in studies related to cerebral ischemia and epilepsy .
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2
2 Cited Publications
Cat. No.: HY-125923
CAS No.: 498-59-9
Purity:  ≥98.0%
Djenkolic acid is a sulfur-containing amino acid. Djenkolic acid can be isolated from the djenkol beans of the Southeast Asian plant Archidendron jiringa. Djenkolic acid de-inhibits the SO4 2- uptake system in Pseudomonas fluorescens. Djenkolic acid causes supersaturation of the urinary system with djenkolic acid crystals, leading to urinary tract obstruction and acute kidney injury .
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2
2 Cited Publications
Cat. No.: HY-N8599
CAS No.: 531-58-8
Cichoriin is an orally active coumarin glycoside with broad biological activities. Cichoriin exhibits inhibitory activities against α-amylase, α-glucosidase, pancreatic lipase and DPP-IV, with IC50 values of 5.76, 2.94, 16.83 and 9.16 μg/mL, respectively. Cichoriin significantly improves metabolic dysfunction-associated steatohepatitis (MASH) in mice by activating the AMPK signaling pathway. Cichoriin upregulates PPAR-γ in adipose tissue and alleviates obesity and associated cardiorenal injury in rats. Cichoriin blocks monosodium urate crystal-induced activation of the NLRP3 inflammasome and cell pyroptosis by inhibiting P2Y14R (IC50 = 8.47 nM). In silico virtual screening reveals that Cichoriin has a strong binding affinity for SARS-CoV-2 .
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2
2 Cited Publications
Cat. No.: HY-N0493
CAS No.: 520-12-7
Pectolinarigenin is an orally active dual inhibitor of COX-2/5-LOX with anti-inflammatory, antioxidant, antitumor and neuroprotective activities. Pectolinarigenin exerts neuroprotective and anti-inflammatory effects on astrocyte inflammation via the NFκB and MAPK pathways. Pectolinarigenin inhibits LPS-induced phosphorylation of ERK1/2, N-FκB and p38MAPK, directly inhibits the enzymatic activity or binding of COX-2, 5-LOX and HIF-1α, and reduces the level of XIAP. Pectolinarigenin modifies Keap1 to promote nuclear accumulation of Nrf2, induces ARE-mediated antioxidant enzyme expression, and possesses direct free radical scavenging activity. Pectolinarigenin reduces the release of NO, proinflammatory mediators and leukotrienes, and increases the level of IL-10. Pectolinarigenin induces G2/M cell cycle arrest, apoptosis (Apoptosis) and autophagy (Autophagy) via the PI3K/AKT/mTOR signaling pathway. Pectolinarigenin reduces renal crystal deposition and inhibits melanin synthesis. Pectolinarigenin inhibits inflammation and alleviates allergy in mouse models of inflammation. Pectolinarigenin alleviates renal injury, inflammation and oxidative stress in mice by inhibiting HIF-1α activity. Pectolinarigenin can be used for the research of neurodegenerative diseases, inflammatory/allergic diseases, calcium oxalate nephrocalcinosis, gastric cancer, melasma, post-inflammatory diseases and chloasma .
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1
1 Cited Publications
Cat. No.: HY-108309
CAS No.: 1984-15-2
Purity:  ≥98.0%
Synonyms: Methylenediphosphonic acid
Research Areas:  

Others

Medronic acid (Methylenediphosphonic acid) is a methylene-substituted bisphosphonate. Medronic acid has an affinity for the surface of hydroxyapatite crystals in the bone matrix and adheres to them. Medronic acid can be used in complex with radioisotopes in bone imaging. Due to its strong metal chelating ability, medronic acid is also used as a water treatment chemical. In addition, medronic acid is used as a solvent additive to improve peak shape and signal of metal-sensitive metabolites in LC/MS analysis .
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1
1 Cited Publications
Cat. No.: HY-19796
CAS No.: 246529-22-6
Synonyms: Aramchol; C20-FABAC
Research Areas:  

Metabolic Disease

Icomidocholic acid (Aramchol) is a lipid molecule synthesized from cholic acid and arachidic acid. Icomidocholic acid is an orally active SCD1 inhibitor and cholesterol solubilizer with antifibrotic effects. Icomidocholic acid can reduce liver fat content, dissolve cholesterol crystals and prevent gallstone formation. Icomidocholic acid can be used in the study of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) .
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1
1 Cited Publications
Cat. No.: HY-139338
CAS No.: 13101-54-7
Purity:  ≥99.0%
Erlose is a trisaccharide sucrose derivative and low-calorie sweetener synthesized from glucose and sucrose via an α-glucosidase-mediated transglycosylation reaction. Erlose is often used as a marker to identify whether honey is adulterated with artificial sucrose. Erlose has approximately half the sweetness of sucrose but a similar taste, and it effectively inhibits crystal formation and browning reactions during food heat treatment .
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1
1 Cited Publications
Cat. No.: HY-B1620H
CAS No.: 9003-39-8
Synonyms: PVP K90; Polyvidone K90; Povidone K90
Polyvinylpyrrolidone K90 can be used to prepare drug delivery systems, such as electrospun nanofibrous membranes. Polyvinylpyrrolidone K90 is widely used in human and veterinary medicine as an effective wound healing promoter and disinfectant when combined with iodine and other compounds. In addition, Polyvinylpyrrolidone K90 is also used to stabilize nanosuspensions, interact with the surface of drug crystals, and remain bound to the surface after drying .
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1
1 Cited Publications
Cat. No.: HY-108844
CAS No.: 134774-45-1
Purity:  95.00%
Rasburicase is a recombinant form of urate oxidase that works by catalyzing the oxidation of uric acid to allantoin, which has a higher solubility. Rasburicase specifically degrades uric acid, rapidly lowers blood uric acid levels, and improves inflammation and kidney damage caused by uric acid crystal deposition. Rasburicase can effectively lower uric acid and prevent uric acid nephropathy, and is used in the study of severe hyperuricemia associated with tumor lysis syndrome (TLS) and refractory gout .
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1
1 Cited Publications
Cat. No.: HY-N0666S4
CAS No.: 55443-54-4
L-Aspartic acid- 13C4 is the 13C-labeled L-Aspartic acid (HY-N0666). L-Aspartic acid is a NMDA receptor agonist and acidic amino acid. L-Aspartic acid has no independent analgesic activity. L-Aspartic acid can antagonize the analgesic effects of D-Aspartic acid and Morphine. L-Aspartic acid regulates polymorph transformation, crystal growth/aggregation and nucleation processes of calcium carbonate, and can serve as a biomineralization template. L-Aspartic acid promotes burst firing of central neurons. L-Aspartic acid can be used in studies related to cerebral ischemia and epilepsy .
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1
1 Cited Publications
Cat. No.: HY-N0666R
CAS No.: 56-84-8
L-Aspartic acid (Standard) is the analytical standard of L-Aspartic acid (HY-N0666). This product is intended for research and analytical applications. L-Aspartic acid is a NMDA receptor agonist and acidic amino acid. L-Aspartic acid has no independent analgesic activity. L-Aspartic acid can antagonize the analgesic effects of D-Aspartic acid and Morphine. L-Aspartic acid regulates polymorph transformation, crystal growth/aggregation and nucleation processes of calcium carbonate, and can serve as a biomineralization template. L-Aspartic acid promotes burst firing of central neurons. L-Aspartic acid can be used in studies related to cerebral ischemia and epilepsy .
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Cat. No.: HY-101064
CAS No.: 35661-60-0
Purity:  99.89%
Synonyms: N-FMOC-leucine; NPC 15199; NSC 334290
Fmoc-Leucine (N-FMOC-leucine) is an anti-inflammatory agent that not only promotes extracellular Ca 2+ influx but also facilitates intracellular Ca 2+ release. Fmoc-Leucine is a selective ligand for PPARγ (Ki = 15 μM), exhibiting insulin-sensitizing effects but with weak fatogenic activity. Fmoc-Leucine exhibits unique self-assembly properties and can form transient gels, stable gels, or crystals/2D sheets through different pathways. Fmoc-Leucine can be used in the research of diabetes, colitis, and bladder cancer .
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Cat. No.: HY-W088065
CAS No.: 141-53-7
Sodium formate acts as a key promoter for heterogeneous nucleation of ZIF crystals and thin film synthesis. It is also recognized as a GRAS substance by the FDA, and serves as a cosmetic preservative and food additive. Sodium formate has low acute oral toxicity (acute oral LD50=7410 mg/kg and acute intravenous LD50=807 mg/kg in mice), with no heritable or carcinogenic effects, but exhibits embryonic developmental toxicity and teratogenicity at high concentrations. Sodium formate may cause moderate irritation to rabbit eyes, is relatively safe to the skin, and does not induce tumor formation in rats in vivo. Sodium formate is rapidly absorbed and oxidized to carbon dioxide in vivo, and forms DNA adducts in specific metabolic deficiency models or upon high-dose exposure .
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Cat. No.: HY-154487
CAS No.: 25637-84-7
Research Areas:  

Neurological Disease

Glycerol dioleate is a lipid capable of forming Lyotropic Liquid Crystal (LLC). When formulated with phosphatidylcholine and exposed to aqueous media, glycerol dioleate constructs an inverted hexagonal (HII) phase structure with sustained-release properties. The in-situ forming gel prepared by optimizing glycerol dioleate with phosphatidylcholine and N-methyl-2-pyrrolidone enables stable release of Risperidone (HY-11018) for up to 60 days in vitro and in vivo. Glycerol dioleate causes minimal side effects in rabbits, making it an ideal carrier component for the development of antischizophrenia agents .Note: Lyotropic liquid crystals (Lyotropic Liquid Crystal, LLC) are ordered fluid phases self-assembled by amphipathic molecules (e.g., lipids, surfactants) in solvents (usually water) at specific concentrations .
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