Art. -Nr.: HY-N0666B

Aspartic acid calcium

(Synonyms: Calcium L-aspartate)

5 Cited Publications

Kundenbewertung

Based on 5 publication(s) in Google Scholar

Aspartic acid calcium (calcium L-aspartate) is a NMDA receptor agonist and acidic amino acid. Aspartic acid calcium has no independent analgesic activity. Aspartic acid calcium can antagonize the analgesic effects of D-Aspartic acid and Morphine. Aspartic acid calcium regulates polymorph transformation, crystal growth/aggregation and nucleation processes of calcium carbonate, and can serve as a biomineralization template. Aspartic acid calcium promotes burst firing of central neurons. Aspartic acid calcium can be used in studies related to cerebral ischemia and epilepsy.

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Reinheit: 98.0%
CAS. Nr.: 10389-09-0
Formel: C₄H₅CaNO₄
Molecular Weight:171.16

Speicherung:

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Aspartic acid calcium Chemical Structure

CAS. Nr.: 10389-09-0

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
- In Vivo
Chemical Information
Publications (5)
Lösungsmittel & Löslichkeit
- In Vitro
Reinheit & Dokumentation
Verweise
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target

NMDA Receptor

Alle iGluR Isoform-spezifische Produkte anzeigen :

In Vitro

Aspartic acid (L-[³H]Asp; 0.05 μCi/mL; 1-120 min) calcium is taken up by rat brain slices, with a slice-to-medium ratio of 2.53 mL/g brain tissue at 120 minutes and an initial uptake rate of 1.22 mL/min/g brain tissue^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Aspartic acid (i.p., 55-230 mg/kg) calcium exhibits no intrinsic analgesic activity at intraperitoneal doses up to 230 mg/kg, but significantly antagonizes the analgesic effects of D-Aspartic acid and Morphine at the intraperitoneal dose of 230 mg/kg^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

BALB/C (both sexes, 25-40 g)^[1]
Dosage:

55 mg/kg; 115 mg/kg; 230 mg/kg
Administration:

i.p.
Result:

Did not cause any antinociceptive effect at doses of 55, 115, and 230 mg/kg.
Significantly inhibited the antinociceptive effect of 115 mg/kg D-aspartic acid at 230 mg/kg.
Shortened the duration of the antinociceptive effect of 5 mg/kg morphine at 230 mg/kg.

Chemical Information

CAS. Nr. 10389-09-0
Appearance Solid
Molecular Weight 171.16
Formel C₄H₅CaNO₄
Color White to off-white
SMILES

N[C@@H](CC([O-])=O)C([O-])=O.[Ca+2]
Synonyms

Calcium L-aspartate
Structure Classification
- Amino acids
Initial Source
- Plants
- other families
- Animals
- Microorganisms
Widespread
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Publications (5)

All Others

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Journal Impact Factor

Nature

Lithocholic acid phenocopies anti-ageing effects of calorie restriction. [Abstract]

2025 Jul;643(8070):192-200. PMID: 39695227
Nat Protoc

An unbiased method for evaluating the genome-wide specificity of base editors in rice. [Abstract]

2021 Jan;16(1):431-457. PMID: 33349703
Redox Biol

Enteric coronavirus PDCoV evokes a non-Warburg effect by hijacking pyruvic acid as a metabolic hub. [Abstract]

2024 May:71:103112. PMID: 38461791

Aspartic acid calcium purchased from MedChemExpress. Usage Cited in: Redox Biol. 2024 May:71:103112. [Abstract]

IPI-2I cells were transfected with an empty vector or the eukaryotic expression plasmid pCAGGS-Flag-SLC1A3, and then infected with PDCoV (MOI = 0.5) in glutamine-containing medium, glutamine-free medium, or glutamine-free medium supplemented with L-Aspartic acid (Asp: 4 mM) or Glu (4 mM).
FASEB J

Maternal LDHB Safeguards Redox Balance and Developmental Competence During Preimplantation Embryo Cleavage. [Abstract]

2026 May 31;40(10):e71888. PMID: 42117986
Amino Acids

Identification of amino acids metabolomic profiling in human plasma distinguishes lupus nephritis from systemic lupus erythematosus. [Abstract]

2024 Sep 18;56(1):56. PMID: 39292313

Lösungsmittel & Löslichkeit

In Vitro:

H₂O : ≥ 100 mg/mL (584.25 mM)

* "≥" means soluble, but saturation unknown.

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

5.8425 mL

29.2124 mL

58.4249 mL

5 mM

1.1685 mL

5.8425 mL

11.6850 mL

10 mM

0.5842 mL

2.9212 mL

5.8425 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (299 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Onat F, et al. Antinociceptive effect of D-aspartic acid in mice. Pharmacology, biochemistry, and behavior. 1995 Aug;51(4):715-9. [Content Brief]

[2]. Hosoya K, et al. Blood-brain barrier produces significant efflux of L-aspartic acid but not D-aspartic acid: in vivo evidence using the brain efflux index method. Journal of neurochemistry. 1999 Sep;73(3):1206-11. [Content Brief]

[3]. Tong H, et al. Control over the crystal phase, shape, size and aggregation of calcium carbonate via a L-aspartic acid inducing process. Biomaterials. 2004 Aug;25(17):3923-9. [Content Brief]

[4]. MacDonald JF, et al. L-Aspartic acid induces a region of negative slope conductance in the current-voltage relationship of cultured spinal cord neurons. Brain research. 1982 Apr 08;237(1):248-53. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
H₂O	1 mM	5.8425 mL	29.2124 mL	58.4249 mL	146.0622 mL
	5 mM	1.1685 mL	5.8425 mL	11.6850 mL	29.2124 mL
	10 mM	0.5842 mL	2.9212 mL	5.8425 mL	14.6062 mL
	15 mM	0.3895 mL	1.9475 mL	3.8950 mL	9.7375 mL
	20 mM	0.2921 mL	1.4606 mL	2.9212 mL	7.3031 mL
	25 mM	0.2337 mL	1.1685 mL	2.3370 mL	5.8425 mL
	30 mM	0.1947 mL	0.9737 mL	1.9475 mL	4.8687 mL
	40 mM	0.1461 mL	0.7303 mL	1.4606 mL	3.6516 mL
	50 mM	0.1168 mL	0.5842 mL	1.1685 mL	2.9212 mL
	60 mM	0.0974 mL	0.4869 mL	0.9737 mL	2.4344 mL
	80 mM	0.0730 mL	0.3652 mL	0.7303 mL	1.8258 mL
	100 mM	0.0584 mL	0.2921 mL	0.5842 mL	1.4606 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Keywords

Aspartic acid calcium

5 Cited Publications

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Aspartic acid calcium

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Publications Citing Use of MedChemExpress (MCE) Aspartic acid calcium

Alle iGluR Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Publications (5)

Lösungsmittel & Löslichkeit

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

Aspartic acid calcium

Immunology/Inflammation Compound Library

Metabolism/Protease Compound Library

Natural Product Library

FDA-Approved Drug Library

Human Endogenous Metabolite Compound Library

Drug Repurposing Compound Library

FDA Approved & Pharmacopeial Drug Library

Microbial Metabolite Library

Food Additive Library

Food-Sourced Compound Library

Inactive Ingredient Library

Plant-Sourced Natural Product Library

Human Metabolite Library

Off-patent Drug Library

Animal-Sourced Natural Product Library

Multi-Target Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Natural Product Library Plus

Drug Repurposing Compound Library Plus

FDA-Approved Drug Library Plus

FDA-Approved Drug Library Mini

Natural Product and Natural Product-Like Compound Library

Bioactive Compound Library

High-Throughput Bioactive Compound Library

High-Throughput Natural Product Library

Flavors and Fragrances Compound Library

Natural Product Diversity Scaffold Library

Publications Citing Use of MedChemExpress (MCE) Aspartic acid calcium

Alle iGluR Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Publications (5)

Lösungsmittel & Löslichkeit

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

Aspartic acid calcium Related Classifications

HY-N0666B Related Classifications