30 Results for "

cyclic+RGD

" in MedChemExpress (MCE) Product Catalog:
Products (30)

30 Results for "cyclic+RGD" in MCE Product Catalog:

8
8 Publications Verification
Art. -Nr.: HY-N6693
CAS. Nr.: 2001-95-8
Synonyms: NSC 122023
Valinomycin is a potassium-specific ionophore, the valinomycin-K + complex can be incorporated into biological bilayer membranes with the hydrophobic surface of valinomycin, destroys the normal K + gradient across the membrane, and as a result kills the cells, incorporating into liposomes can significantly reduces the cytotoxicity and enhances the targeting effect. Valinomycin exhibits antibiotic, antifungal, antiviral, antitumor and insecticidal efficacy, thus can be used for relevant research .
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2
2 Cited Publications
Art. -Nr.: HY-166648
Target:  

Liposome

Forschungsgebiete:  

Cancer

DSPE-PEG2000-Maleimide sodium (purity>98%) is a functional lipid component and a thiol-reactive crosslinker. DSPE-PEG2000-Maleimide sodium (purity>98%) undergoes Michael addition with the thiol groups of thiolated or cyclic RGD peptides to form stable thioether bonds and DSPE-PEG2000-RGD. DSPE-PEG2000-Maleimide sodium (purity>98%) is applicable to research on drug delivery .
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2
2 Cited Publications
Art. -Nr.: HY-P2300
CAS. Nr.: 862772-11-0
Synonyms: Cyclo(RGDfC)
Target:  

Integrin

Forschungsgebiete:  

Cancer

Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC), a cyclic RGD peptide which has high affinity to αvβ3, can disrupt cell integrin interactions. Cyclo(Arg-Gly-Asp-D-Phe-Cys) inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo. Cyclo(Arg-Gly-Asp-D-Phe-Cys) can be used in the research of tumors .
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2
2 Cited Publications
Art. -Nr.: HY-166648A
Target:  

Liposome

Forschungsgebiete:  

Others

DSPE-PEG-Maleimide ammonium (MW 2000) is a functional lipid component and a thiol-reactive crosslinker. DSPE-PEG-Maleimide ammonium (MW 2000) undergoes Michael addition with the thiol groups of thiolated or cyclic RGD peptides to form stable thioether bonds and DSPE-PEG (2000)-RGD. DSPE-PEG-Maleimide ammonium (MW 2000) is applicable to research on drug delivery .
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2
2 Cited Publications
Art. -Nr.: HY-P2300A
Synonyms: Cyclo(RGDfC) TFA
Target:  

Integrin

Forschungsgebiete:  

Cancer

Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC) TFA, a cyclic RGD peptide which has high affinity to αvβ3, can disrupt cell integrin interactions. Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo. Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA can be used in the research of tumors .
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1
1 Cited Publications
Art. -Nr.: HY-P1206
CAS. Nr.: 174688-78-9
Target:  

Somatostatin Receptor

Forschungsgebiete:  

Neurological Disease

CH 275 is a peptide analog of somatostatin and binds preferably to somatostatin receptor 1 (sst1) with a Ki of 52 nM . CH 275 acts as a potent and selective sst1 agonist (IC50=30.9 nM) and also displays IC50 values of 345 nM, >1 μM, >10 μM, >10 μM for human sst3, sst4, sst2 and sst5, respectively . CH 275 can be used for the research of alzheimer’s disease .
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Art. -Nr.: HY-P10033
CAS. Nr.: 245080-24-4
Target:  

Ser/Thr Protease

Forschungsgebiete:  

Others

SFTI-1 is a cyclic peptide trypsin inhibitor consisting of 14 amino acid residues. SFTI-1 belongs to the Bowman-Birk class of inhibitors. Characterized by its small size, high stability, and potent activity, SFTI-1 can be used for research on peptide drug design platforms .
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Art. -Nr.: HY-P5021
CAS. Nr.: 756500-22-8
Synonyms: c(RGDfE)
Target:  

Integrin

Forschungsgebiete:  

Cancer

Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) c(RGDfE) is a cyclic RGD peptide targeting integrin αvβ3. Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) is commonly used for modifying drug loaded nanoparticles. Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) is often used in cancer research, such as pancreatic cancer .
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Art. -Nr.: HY-P4102
CAS. Nr.: 1810853-35-0
Target:  

Peptides

Forschungsgebiete:  

Cancer

Cyclic PSAP peptide is a cyclic pentapeptide (DWLPK). Cyclic PSAP peptide exhibits agent-like properties and could inhibit metastatic spread and restrain tumor development in general in vivo .
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Art. -Nr.: HY-P3193A
Forschungsgebiete:  

Others

Cyclic nona-L-arginine hydrochloride, a nonaarginine peptide used for drug delivery, translocates faster than their linear counterparts .
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Art. -Nr.: HY-P10027A
Target:  

Antibiotic Bacterial

Forschungsgebiete:  

Infection

Clovibactin TFA is the TFA salt form of Clovibactin (HY-P10027). Clovibactin TFA is an antibiotic for drug-resistant bacterial pathogens without detectable resistance. Clovibactin TFA inihibits cell wall synthesis by targeting pyrophosphate of peptidoglycan precursors .
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Art. -Nr.: HY-P10027
CAS. Nr.: 2247194-77-8
Target:  

Antibiotic Bacterial

Forschungsgebiete:  

Infection

Clovibactin is an antibiotic for drug-resistant bacterial pathogens without detectable resistance. Clovibactin TFA inihibits cell wall synthesis by targeting pyrophosphate of peptidoglycan precursors .
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Art. -Nr.: HY-P11424
CAS. Nr.: 128857-77-2
Target:  

Integrin

Forschungsgebiete:  

Cancer

Cyclo(GRGDSPA) is a cyclic RGD peptide targeting αvβ3 integrin. Cyclo(GRGDSPA) reduces the formation of colonies in mice injected with B16-FE7 melanoma cells. Cyclo(GRGDSPA) can be used for melanoma research .
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Art. -Nr.: HY-P4320
CAS. Nr.: 166184-23-2
Target:  

Integrin

Forschungsgebiete:  

Cancer

Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys (Disulfide bridge: Cys1-Cys10), a decapeptide containing a cyclic RGD active sequence, is an Integrin αIIbβ3 antagonist that inhibits platelet and Adhesion of proMMP-13 .
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Art. -Nr.: HY-P3193
Target:  

Peptides

Forschungsgebiete:  

Others

Cyclic nona-L-arginine TFA, a nonaarginine peptide used for drug delivery, translocates faster than their linear counterparts .
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Art. -Nr.: HY-P11428
CAS. Nr.: 2425606-55-7
Forschungsgebiete:  

Others

DBCO-cyclo (RGDfK) is a clickable DBCO-modified cyclic RGD peptide, and also a DBCO derivative of cyclo (RGDfK) (HY-P0023). DBCO-cyclo (RGDfK) is synthesized via an amide coupling reaction between DBCO-NHS ester and cyclo (RGDfK). DBCO-cyclo (RGDfK) can react with azide groups through copper-free click chemistry (SPAAC) to immobilize RGD peptides onto biomaterials or hydrogels. The RGD sequence in DBCO-cyclo (RGDfK) is recognizable by cellular integrins and promotes cell adhesion. DBCO-cyclo (RGDfK) can be used in studies related to tissue engineering, 3D cell culture, and surface functionalization of biomaterials .
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Art. -Nr.: HY-P10672
Forschungsgebiete:  

Others

SEI144 is a low nanomolar binder of USP15 and does not inhibit USP15 activity .
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Art. -Nr.: HY-P11774
CAS. Nr.: 1094848-99-3
Target:  

Integrin

Forschungsgebiete:  

Cancer

HYNIC-3P-RGD2 is a dimeric cyclic RGD peptide with high binding affinity for integrin αvβ3 (IC50 = 33 nM). HYNIC-3P-RGD2 acts as a precursor molecule for radiotracers and is used to detect tumor angiogenesis .
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Art. -Nr.: HY-P11773
CAS. Nr.: 1094848-94-8
Forschungsgebiete:  

Others

3P-RGD2 is a dimeric cyclic RGD (Arg-Gly-Asp) peptide. When radiolabeled with 99mTc, 3P-RGD2 serves as a selective radiotracer for integrin αvβ3. When radiolabeled with 99mTc, 3P-RGD2 enables single-photon emission computed tomography imaging of integrin αvβ3 .
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Art. -Nr.: HY-187311A
Alkyne-PEG2000-cRGD is a functionalized PEGylated lipid conjugate composed of three modular components: alkyne (propargyl/alkyne linker) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and cyclic RGD peptide (cyclo(Arg-Gly-Asp)) as the terminal targeting/functional ligand. Alkyne-PEG2000-cRGD does not contain a lipid anchoring group but instead provides a terminal reactive site for post-assembly ligand or probe conjugation on PEGylated nanoparticles.
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