862772-11-0
Chemical Structure
Cyclo(Arg-Gly-Asp-D-Phe-Cys)
Synonym(s): Cyclo(RGDfC)
- CAS No.: 862772-11-0
- Formula:C24H34N8O7S
- Molecular Weight:578.64
InChIKey: WNYJVAMZRBTOPE-YVSFHVDLSA-N
SMILES: O=C([C@@H](CC1=CC=CC=C1)NC([C@H](CC(O)=O)NC(CNC2=O)=O)=O)N[C@@H](CS)C(N[C@H]2CCCNC(N)=N)=O
Biological Activity: Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC), a cyclic RGD peptide which has high affinity to αvβ3, can disrupt cell integrin interactions. Cyclo(Arg-Gly-Asp-D-Phe-Cys) inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo. Cyclo(Arg-Gly-Asp-D-Phe-Cys) can be used in the research of tumors[1].
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Cyclo(Arg-Gly-Asp-D-Phe-Cys) | 98.08% | Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC), a cyclic RGD peptide which has high affinity to αvβ3, can disrupt cell integrin interactions. Cyclo(Arg-Gly-Asp-D-Phe-Cys) inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo. Cyclo(Arg-Gly-Asp-D-Phe-Cys) can be used in the research of tumors. | ||||||||||||||||||||
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Keywords
