756500-22-8
756500-22-8
Chemical Structure
Cyclo(Arg-Gly-Asp-(D-Phe)-Glu)
Synonym(s): c(RGDfE)
- CAS No.: 756500-22-8
- Formula:C26H36N8O9
- Molecular Weight:604.61
InChIKey: LHYAAFPJZDQDLU-FJIDUMEYSA-N
SMILES: O=C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N1)=O)CC(O)=O)=O)=O)CCCNC(N)=N)=O)CCC(O)=O)[C@H]1CC2=CC=CC=C2
Biological Activity: Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) c(RGDfE) is a cyclic RGD peptide targeting integrin αvβ3. Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) is commonly used for modifying drug loaded nanoparticles. Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) is often used in cancer research, such as pancreatic cancer[1][2].
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Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) | 99.94% | Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) c(RGDfE) is a cyclic RGD peptide targeting integrin αvβ3. Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) is commonly used for modifying drug loaded nanoparticles. Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) is often used in cancer research, such as pancreatic cancer. | ||||||||||||||||||||
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References
- [1]. Kim DH, et al. Deoxycholate bile acid directed synthesis of branched Au nanostructures for near infrared photothermal ablation. Biomaterials. 2015 Jul;56:154-64. [Content Brief]
- [2]. Sun J , et al. A c(RGDfE) conjugated multi-functional nanomedicine delivery system for targeted pancreatic cancer therapy. J Mater Chem B. 2015 Feb 14;3(6):1049-1058. [Content Brief]
Keywords
