Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
cyclin-dependent kinase 4
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "cyclin-dependent kinase 4" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P702682
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK4; cyclin-dependent kinase 4; cyclin dependent kinase 4; cyclin-dependent kinase; PSK-J3; MCPH31; Cell Division Protein kinase 4; CMM3; CCND1; B-Cell CLL/Lymphoma 1; Prev. PRAD1; PRAD1 Oncogene; Prev. BCL1; Parathyroid Adenomatosis 1; Prev. D11S287E; C
Species:
Human
Source:
Sf9 insect cells
1
1 Cited Publications
Cat. No.: HY-P86438
Synonyms: cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3; cyclin-dependent kinase 4 inhibitor A; CDK4I; Multiple tumor suppressor 1; MTS-1; p16-INK4a; p16-INK4; p16INK4A; p16;
1
1 Cited Publications
Cat. No.: HY-P80615
Synonyms: CDK4 inhibitor p16 INK4 antibody;
CDK4I antibody;
CDKN2 antibody;
CDKN2A antibody;
Cell cycle negative regulator beta antibody;
CMM2 antibody;
cyclin dependent kinase 4 inhibitor A antibody;
cyclin dependent kinase inhibitor 2A (melanoma p16 inhibits CDK4) antibody;
cyclin dependent kinase Inhibitor 2A antibody;
cyclin dependent kinase inhibitor 2A isoform 4 antibody;
cyclin dependent kinase inhibitor 2A isoforms 1/2/3 antibody;
cyclin dependent kinase inhibitor p16 antibody;
INK4 antibody;
INK4A antibody;
MLM antibody;
MTS1 antibody;
Multiple tumor suppressor 1 antibody;
p14 antibody;
p16 antibody;
P16INK4 antibody;
p16INK4a antibody;
p19 antibody;
p19Arf antibody;
TP16 antibody;
Cat. No.: HY-164129
CAS No.: 3002399-75-6
CDK4-IN-3 (Compound 389) is a potent irreversible cyclin-dependent kinase 4 (CDK4) inhibitor (IC50=25 nM, >10-fold selective over CDK6). CDK4-IN-3 arrests the cell cycle at G₁ phase, and induces tumor cell apoptosis. CDK4-IN-3 is promising for research of solid tumors such as breast and lung cancers .
Cat. No.: HY-146213
CAS No.: 2445205-24-1
CDK4/6-IN-12 is a potent cyclin-dependent kinase 4/6 (CDK4/6) inhibitor. CDK4/6-IN-12 has enzymatic inhibitory activity for CDK4 and CDK6 with IC50 of 592.3 nM and 3090 nM, respectively. CDK4/6-IN-12 can be used for the research of cancer .
Cat. No.: HY-P704003
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK4; cyclin-dependent kinase 4; cyclin dependent kinase 4; cyclin-dependent kinase; PSK-J3; MCPH31; Cell Division Protein kinase 4; CMM3
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702684
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK4; cyclin-dependent kinase 4; cyclin dependent kinase 4; cyclin-dependent kinase; PSK-J3; MCPH31; Cell Division Protein kinase 4; CMM3; CCND3; G1/S-Specific cyclin-D3; cyclin D3; D3-Type cyclin
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702683
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: CDK4; cyclin-dependent kinase 4; cyclin dependent kinase 4; cyclin-dependent kinase; PSK-J3; MCPH31; Cell Division Protein kinase 4; CMM3; CCND2; G1/S-Specific cyclin D2; cyclin D2; KIAK0002; G1/S-Specific cyclin-D2; MPPH3
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P70034
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CDKN2C; P18-INK4c; cyclin dependent kinase Inhibitor 2C; cyclin-dependent kinase 6 Inhibitor P18; cyclin-dependent kinase 4 Inhibitor C; cyclin-dependent kinase Inhibitor 2C; P18-INK6; cyclin-dependent Inhibitor; INK4C; CDK6 Inhibitor P18; P18; P18-INK4C
Species:
Human
Source:
E. coli
Cat. No.: HY-133956
CAS No.: 129821-08-5
Synonyms: NSC 680434
Research Areas:
3-ATA (NSC 680434) is a selective inhibitor of cyclin-dependent kinase 4 (CDK4) with neuroprotective and antitumor effects. 3-ATA can alleviate kainic acid (HY-N2309)-induced apoptosis in cerebellar granule neurons, which can be used in the study of neurodegenerative diseases .
Cat. No.: HY-P74659
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CDKN2D; Cell Cycle Inhibitor, Nur77 Associating Protein; cyclin dependent kinase Inhibitor 2D; cyclin-dependent kinase 4 Inhibitor D P19; INK4D; Inhibitor Of cyclin-dependent kinase 4d; P19; CDK Inhibitor P19INK4d; cyclin-dependent kinase Inhibitor 2D (P1
Species:
Human
Source:
E. coli
Cat. No.: HY-P85531
Synonyms: Cdk 4; cdk4; CDK4 protein; CDK4_HUMAN; Cell division kinase 4; Cell division protein kinase 4; CMM 3; CMM3; Crk3; cyclin dependent kinase 4; cyclin-dependent kinase 4; Melanoma cutaneous malignant 3; MGC14458; p34 cdk4; PSK J3; PSK-J3.
Cat. No.: HY-P85098
Synonyms: CDK9; CDC2L4; TAK; cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; Serine/threonine-protein kinase PITALRE; Tat-associated kinase complex catalytic subunit
Cat. No.: HY-179688
PROTAC CDK2/4 Degrader-1 is a PROTAC degrader of cyclin-dependent kinase 2 (CDK2) and cyclin-dependent kinase 4 (CDK4). PROTAC CDK2/4 Degrader-1 induces degradation via the ubiquitin-proteasome pathway. PROTAC CDK2/4 Degrader-1 can be used in cancer research .
Cat. No.: HY-P87922
Synonyms: CDC2L4, TAK, CDK9, cyclin-dependent kinase 9, C-2K, Cell division cycle 2-like protein kinase 4, Cell division protein kinase 9, Serine/threonine-protein kinase PITALRE, Tat-associated kinase complex catalytic subunit
Cat. No.: HY-P80615A
Synonyms: CDK4 inhibitor p16 INK4 antibody;
CDK4I antibody;
CDKN2 antibody;
CDKN2A antibody;
Cell cycle negative regulator beta antibody;
CMM2 antibody;
cyclin dependent kinase 4 inhibitor A antibody;
cyclin dependent kinase inhibitor 2A (melanoma p16 inhibits CDK4) antibody;
cyclin dependent kinase Inhibitor 2A antibody;
cyclin dependent kinase inhibitor 2A isoform 4 antibody;
cyclin dependent kinase inhibitor 2A isoforms 1/2/3 antibody;
cyclin dependent kinase inhibitor p16 antibody;
INK4 antibody;
INK4A antibody;
MLM antibody;
MTS1 antibody;
Multiple tumor suppressor 1 antibody;
p14 antibody;
p16 antibody;
P16INK4 antibody;
p16INK4a antibody;
p19 antibody;
p19Arf antibody;
TP16 antibody;
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
