23 Results for "

delta-like ligand 3

" in MedChemExpress (MCE) Product Catalog:
Products (23)

23 Results for "delta-like ligand 3" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P99575
CAS No.: 2307488-83-9
Synonyms: AMG-757

Target:  

Notch

Research Areas:  

Inflammation/Immunology Cancer

Tarlatamab (AMG-757) is a bispecific T-cell engager (BiTE) antibody targeting delta-like ligand 3 (DLL3). DLL3 is a target that is selectively expressed in small-cell lung cancer (SCLC) tumors, but with minimal normal tissue expression. Tarlatamab has the KDs of 0.64 nM and 0.50 nM for human and nonhuman primate (NHP) DLL3, respectively. Tarlatamab has the KDs of 14.9 nM and 12 nM for human and NHP CD3, respectively. Tarlatamab is a first-in-class HLE BiTE immuno-oncology therapy targeting DLL3 and has the potential for SCLC research .
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Cat. No.: HY-P990932
CAS No.: 2851943-09-2
Synonyms: BI 764532; OBT 620

Target:  

CD3

Research Areas:  

Cancer

Obrixtamig (BI 764532; OBT 620) is an CD3E/DLL3-targeting L-κ-G1-h-CH2-CH3_L-λ-G1-h-CH2-CH3 type human antibody. Obrixtamig is a delta-like ligand 3 (DLL3)/CD3 IgG-like T-cell engager. Obrixtamig can be used for research of DLL3-positive small cell lung cancer .
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Cat. No.: HY-P991731
Synonyms: ZG006
Target:  

CD3 Notch

Research Areas:  

Neurological Disease Cancer

Alveltamig (ZG006) is a trispecific T cell engager targeting Delta-like ligand 3 (DLL3)/CD3, mediating T cell-specific killing of DLL3-expressing tumor cells. Alveltamig can be used for the researches of small cell lung cancer and neuroendocrine carcinoma .
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Cat. No.: HY-159072
CAS No.: 2575682-08-3
Purity:  96.22%
Research Areas:  

Cancer

Mal-Val-Ala-PAB-N(SO2Me)-Exatecan (Compound LE14) is a conjugate of an ADC toxin Exatecan (HY-13631) and a linker Mal-Val-Ala-PAB-N(SO2Me). Mal-Val-Ala-PAB-N(SO2Me)-Exatecan can be used for synthesis of ADC FZ-AD005. FZ-AD005 is a delta-like ligand 3 (DLL3, KD=58.3 pM) targeting ADC, that exhibits antitumor efficacy against SCLC cancer .
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Cat. No.: HY-P990896

Target:  

ADC Antibodies

Research Areas:  

Cancer

FZ-A038 is a delta-like ligand 3 (DLL3) targeted, humanized monoclonal antibody. FZ-A038 can be used for synthesis of DLL3 targeting ADC FZ-AD005 (HY-164729) .
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Cat. No.: HY-P71852
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DLL3; delta3; delta like Canonical Notch ligand 3; delta (Drosophila)-like 3; SCDO1; delta-like 3 (Drosophila); Drosophila delta Homolog 3; delta-like 3; delta-like Protein 3
Species:  
Human
Source:  
P. pastoris
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Cat. No.: HY-P77641
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: DLL3; delta3; delta like Canonical Notch ligand 3; delta (Drosophila)-like 3; SCDO1; delta-like 3 (Drosophila); Drosophila delta Homolog 3; delta-like 3; delta-like Protein 3
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P77916
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: DLL3; delta3; delta like Canonical Notch ligand 3; delta (Drosophila)-like 3; SCDO1; delta-like 3 (Drosophila); Drosophila delta Homolog 3; delta-like 3; delta-like Protein 3
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P78115
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: DLL3; delta3; delta like Canonical Notch ligand 3; delta (Drosophila)-like 3; SCDO1; delta-like 3 (Drosophila); Drosophila delta Homolog 3; delta-like 3; delta-like Protein 3
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P700456
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DLL3; delta3; delta like Canonical Notch ligand 3; delta (Drosophila)-like 3; SCDO1; delta-like 3 (Drosophila); Drosophila delta Homolog 3; delta-like 3; delta-like Protein 3
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P700982
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DLL3; delta3; delta like Canonical Notch ligand 3; delta (Drosophila)-like 3; SCDO1; delta-like 3 (Drosophila); Drosophila delta Homolog 3; delta-like 3; delta-like Protein 3
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704565
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DLL3; delta3; delta like Canonical Notch ligand 3; delta (Drosophila)-like 3; SCDO1; delta-like 3 (Drosophila); Drosophila delta Homolog 3; delta-like 3; delta-like Protein 3
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P77642
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: DLL3; delta3; delta like Canonical Notch ligand 3; delta (Drosophila)-like 3; SCDO1; delta-like 3 (Drosophila); Drosophila delta Homolog 3; delta-like 3; delta-like Protein 3
Species:  
Rhesus Macaque
Source:  
HEK293
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Cat. No.: HY-P701306
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DLL3; delta3; delta like Canonical Notch ligand 3; delta (Drosophila)-like 3; SCDO1; delta-like 3 (Drosophila); Drosophila delta Homolog 3; delta-like 3; delta-like Protein 3
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P703931
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DLL3; delta3; delta like Canonical Notch ligand 3; delta (Drosophila)-like 3; SCDO1; delta-like 3 (Drosophila); Drosophila delta Homolog 3; delta-like 3; delta-like Protein 3
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704563
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DLL3; delta3; delta like Canonical Notch ligand 3; delta (Drosophila)-like 3; SCDO1; delta-like 3 (Drosophila); Drosophila delta Homolog 3; delta-like 3; delta-like Protein 3
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704564
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DLL3; delta3; delta like Canonical Notch ligand 3; delta (Drosophila)-like 3; SCDO1; delta-like 3 (Drosophila); Drosophila delta Homolog 3; delta-like 3; delta-like Protein 3
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704566
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DLL3; delta3; delta like Canonical Notch ligand 3; delta (Drosophila)-like 3; SCDO1; delta-like 3 (Drosophila); Drosophila delta Homolog 3; delta-like 3; delta-like Protein 3
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P705151
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DLL3; delta3; delta like Canonical Notch ligand 3; delta (Drosophila)-like 3; SCDO1; delta-like 3 (Drosophila); Drosophila delta Homolog 3; delta-like 3; delta-like Protein 3
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P991173

Target:  

Notch

Research Areas:  

Cancer

AMG-119 is a humanized IgG1 monoclonal antibody that targets delta-like ligand 3 (DLL3). AMG-119 can be used for the study of relapsed/refractory (R/R) small cell lung cancer (SCLC). Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) .
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