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Obrixtamig

(Synonyms: BI 764532; OBT 620)
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Based on 1 Customer Validation

Obrixtamig (BI 764532; OBT 620) is an CD3E/DLL3-targeting L-κ-G1-h-CH2-CH3_L-λ-G1-h-CH2-CH3 type human antibody. Obrixtamig is a delta-like ligand 3 (DLL3)/CD3 IgG-like T-cell engager. Obrixtamig can be used for research of DLL3-positive small cell lung cancer.

For research use only. We do not sell to patients.

  • Purity: 99.9%
  • CAS No.: 2851943-09-2
  • Molecular Weight:152.03 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Obrixtamig
  • Experimental Validation Results for Obrixtamig
  • Experimental Validation Results for Obrixtamig
  • Experimental Validation Results for Obrixtamig
  • Obrixtamig Chemical Structure
  • Experimental Validation Results for Obrixtamig
  • Experimental Validation Results for Obrixtamig
  • Experimental Validation Results for Obrixtamig
  • Experimental Validation Results for Obrixtamig
  • Obrixtamig Chemical Structure
    Obrixtamig Chemical Structure
CAS No.: 2851943-09-2
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609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    L-kappa-IgG1_L-lambda-IgG1

  • 1/16

    Immobilized CD3 epsilon Protein, Human (HEK293, His, HY-P70506) can bind Obrixtamig. The EC50 for this effect is 780.7 ng/mL.

  • 1/16

    Immobilized Delta-like protein 3/DLL3 Protein, Human (Biotinylated, HEK293, His HY-P78115) can bind Obrixtamig. The EC50 for this effect is 3.458 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 Juakat cells with Obrixtamig (HY-P990932, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Obrixtamig Chemical Structure
    1/16
  • Obrixtamig
  • Immobilized CD3 epsilon Protein, Human (HEK293, His, HY-P70506) can bind Obrixtamig. The EC50 for this effect is 780.7 ng/mL.
  • Immobilized Delta-like protein 3/DLL3 Protein, Human (Biotinylated, HEK293, His HY-P78115) can bind Obrixtamig. The EC50 for this effect is 3.458 ng/mL.
  • Flow cytometric analysis of 1X106 Juakat cells with Obrixtamig (HY-P990932, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • L-kappa-IgG1_L-lambda-IgG1