34 Results for "

dendritic cell (DC)

" in MedChemExpress (MCE) Product Catalog:
Products (34)

34 Results for "dendritic cell (DC)" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99742
CAS No.: 2055640-86-1
Synonyms: ADC-1013; JNJ-64457107; Vanalimab

Target:  

TNF Receptor

Research Areas:  

Cancer

Mitazalimab (ADC-1013; JNJ-64457107) is FcγR-dependent CD40 agonist with tumor-directed activity. Mitazalimab activates antigen-presenting cells, e.g. dendritic cells (DC), to initiate tumor-reactive T cells. Therefore, Mitazalimab induces tumor-specific T cells to infiltrate and kill tumors. Mitazalimab remodels the tumor-infiltrating myeloid microenvironment .
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Cat. No.: HY-P990273

Target:  

CD38 ERK CD1 Apoptosis

Research Areas:  

Cancer

Anti-Mouse CD38 Antibody (NIMR5) is an anti-mouse CD38 IgG2a monoclonal antibody. Anti-Mouse CD38 Antibody (NIMR5) can activate the ERK signaling pathway and promote cell apoptosis. Anti-Mouse CD38 Antibody (NIMR5) can restore T cell function. Anti-Mouse CD38 Antibody (NIMR5) upregulates the expression of CD1d protein and enhances spleen cell proliferation, dendritic cell (DC) and natural killer T cell (NKT) expansion. Anti-Mouse CD38 Antibody (NIMR5) can be used for researches on cancer and immunology such as melanoma and colon cancer .
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Cat. No.: HY-W159303
CAS No.: 17771-33-4
Research Areas:  

Others

7-Hydroxy-2,2-dimethyl-4-chromanone (compound 41) is an inhibitor of DC-SIGN (Dendritic Cell-Specific Intercellular Adhesion Molecule 3 grabbing non-integrin), with an IC50 of 4.66 mM . DC-SIGN is the C-type lectin receptor presenting on the surface of both macrophages and dendritic cells .
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Cat. No.: HY-D1056C3
Synonyms: LPS, from Salmonella enterica (Serotype typhimurium)
Lipopolysaccharides, from S. enterica (Salmonella enterica) serotype typhimurium are lipopolysaccharide endotoxins and TLR4 activators derived from serotype typhimurium of Salmonella enterica, and are classified as S-type LPS. Lipopolysaccharides, from S. enterica exhibit a typical three-part structure: O-antigen, core oligosaccharide, and lipid A. Lipopolysaccharides, from S. enterica serotype typhimurium can modulate the fate of bacteria in dendritic cells (DC), determining the uptake, degradation, and activation of immune functions by DC cells against the bacteria .
It is recommended to prepare a solution with concentration ≥2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.
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Cat. No.: HY-176755
CAS No.: 943316-60-7
Research Areas:  

Inflammation/Immunology

CCL-34 is a Toll-like receptor 4 (TLR4) activator. CCL-34 significantly induced dendritic cell (DC) CD83 expression and IL-12p70 production in a dose-dependent manner, thereby inducing DC maturation. CCL-34 enhanced the allostimulatory activity of DC on naive CD4+CD45+RA+ T cell proliferation and IFN-γ secretion. CCL-34 further induced antigen presentation ability in mice inoculated with doxorubicin-treated colorectal cancer cells. CCL-34 can be used in studies of immune stimulation.
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Cat. No.: HY-175876
CAS No.: 1802395-34-1
Target:  

MMP Interleukin Related

Research Areas:  

Inflammation/Immunology

ADAM17-IN-1 is a selective inhibitor of ADAM17. ADAM17-IN-1 inhibits ADAM17 activity to reduce metabolic activity of dendritic cells (DCs), impair DC antigen-presenting function, suppress allergen-specific Th2 cell polarization, and reduce Th2 cytokine (IL-4, IL-5, IL-13) secretion. ADAM17-IN-1 demonstrates protective efficacy against house dust mite (HDM)-induced type 2/eosinophilic airway inflammation in mice. ADAM17-IN-1 can be used for the study of type 2-high allergic asthma .
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Cat. No.: HY-175421
Research Areas:  

Cancer

ArMan is a co-activator of DC-SIGN (CD209) and TLR7. ArMan can selectively bind to DC-SIGN, promoting receptor-mediated endocytosis of the virus-like particle (VLP) platform, thereby enhancing co-binding with TLR7. ArMan can drive dendritic cell activation, shifting the immune response from humoral immunity to type 1 cellular immunity. ArMan can be used in melanoma research .
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Cat. No.: HY-P991800

Research Areas:  

Inflammation/Immunology

Anti-Mouse Dendritic Cells Antibody (33D1) reacts with the mouse dendritic cells. Dendritic cells (DC) are a small subpopulation of lymphoid cells with distinctive cytologic features, surface properties, and functions. Recommend Isotype Controls: Rat IgG2b kappa, Isotype Control (HY-P990682) .
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Cat. No.: HY-P70110
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD209; dendritic cell-Specific ICAM-3-Grabbing Non-Integrin 1; CD209 Molecule; C-Type Lectin Domain Family 4 Member L; DC-SIGN1; dendritic cell-Specific Intracellular Adhesion Molecules (ICAM)-3 Grabbing Non-Integrin; DC-SIGN; dendritic cell-Specific Inte
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P74205
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD209; dendritic cell-Specific ICAM-3-Grabbing Non-Integrin 1; CD209 Molecule; C-Type Lectin Domain Family 4 Member L; DC-SIGN1; dendritic cell-Specific Intracellular Adhesion Molecules (ICAM)-3 Grabbing Non-Integrin; DC-SIGN; dendritic cell-Specific Inte
Species:  
Rhesus Macaque
Source:  
HEK293
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Cat. No.: HY-P76643
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD209; dendritic cell-Specific ICAM-3-Grabbing Non-Integrin 1; CD209 Molecule; C-Type Lectin Domain Family 4 Member L; DC-SIGN1; dendritic cell-Specific Intracellular Adhesion Molecules (ICAM)-3 Grabbing Non-Integrin; DC-SIGN; dendritic cell-Specific Inte
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P704561
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD209; dendritic cell-Specific ICAM-3-Grabbing Non-Integrin 1; CD209 Molecule; C-Type Lectin Domain Family 4 Member L; DC-SIGN1; dendritic cell-Specific Intracellular Adhesion Molecules (ICAM)-3 Grabbing Non-Integrin; DC-SIGN; dendritic cell-Specific Inte
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P74206
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD209; dendritic cell-Specific ICAM-3-Grabbing Non-Integrin 1; CD209 Molecule; C-Type Lectin Domain Family 4 Member L; DC-SIGN1; dendritic cell-Specific Intracellular Adhesion Molecules (ICAM)-3 Grabbing Non-Integrin; DC-SIGN; dendritic cell-Specific Inte
Species:  
Rhesus Macaque
Source:  
HEK293
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Cat. No.: HY-P83614
Synonyms: CD209; CLEC4L; CD209 antigen; C-type lectin domain family 4 member L; dendritic cell-specific ICAM-3-grabbing non-integrin 1; DC-SIGN; DC-SIGN1; CD209

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

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Cat. No.: HY-P72739
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CLEC4M; dendritic cell-Specific ICAM-3-Grabbing Non-Integrin 2; Prev. CD209L; DC-SIGN-Related Protein; Prev. CD299; L-SIGN; DC-SIGNR; Liver/Lymph Node-Specific ICAM-3 Grabbing Non-Integrin; DC-SIGN2; Liver/Lymph Node-Specific ICAM-3-Grabbing Non-Integrin
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P76219A
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CLEC4M; dendritic cell-Specific ICAM-3-Grabbing Non-Integrin 2; Prev. CD209L; DC-SIGN-Related Protein; Prev. CD299; L-SIGN; DC-SIGNR; Liver/Lymph Node-Specific ICAM-3 Grabbing Non-Integrin; DC-SIGN2; Liver/Lymph Node-Specific ICAM-3-Grabbing Non-Integrin
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P76219
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CLEC4M; dendritic cell-Specific ICAM-3-Grabbing Non-Integrin 2; Prev. CD209L; DC-SIGN-Related Protein; Prev. CD299; L-SIGN; DC-SIGNR; Liver/Lymph Node-Specific ICAM-3 Grabbing Non-Integrin; DC-SIGN2; Liver/Lymph Node-Specific ICAM-3-Grabbing Non-Integrin
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P7399
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PDCD1LG2; B7 dendritic cell Molecule; Programmed cell Death 1 Ligand 2; Programmed Death Ligand 2; PD-L2; Butyrophilin B7-DC; CD273; PDCD1 Ligand 2; B7-DC; PDCD1L2; PDL2; PD-1-Ligand 2; B7DC; CD273 Antigen; BA574F11.2; PD-1 Ligand 2; Btdc
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P70734
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PDCD1LG2; B7 dendritic cell Molecule; Programmed cell Death 1 Ligand 2; Programmed Death Ligand 2; PD-L2; Butyrophilin B7-DC; CD273; PDCD1 Ligand 2; B7-DC; PDCD1L2; PDL2; PD-1-Ligand 2; B7DC; CD273 Antigen; BA574F11.2; PD-1 Ligand 2; Btdc
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P72492
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PDCD1LG2; B7 dendritic cell Molecule; Programmed cell Death 1 Ligand 2; Programmed Death Ligand 2; PD-L2; Butyrophilin B7-DC; CD273; PDCD1 Ligand 2; B7-DC; PDCD1L2; PDL2; PD-1-Ligand 2; B7DC; CD273 Antigen; BA574F11.2; PD-1 Ligand 2; Btdc
Species:  
Human
Source:  
HEK293
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