5 Results for "

ear thickness

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "ear thickness" in MCE Product Catalog:

Cat. No.: HY-178302
CAS No.: 2882900-86-7
Target:  

ADC Payloads

Research Areas:  

Others

TNF-α agonistic 2 (Compound 009) is a toxic molecule. TNF-α agonistic 2 reduces the thickness of the right ear in mice. TNF-α agonistic 2 can be used as an ADC toxic molecule .
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Cat. No.: HY-N11080
CAS No.: 55903-92-9
Cucurbitacin R is an orally active anti-inflammatory agent. Cucurbitacin R is isolated from the roots of Cayaponia tayuya. Cucurbitacin R inhibits Cyclooxygenase-2. Cucurbitacin R inhibits Interleukin-6-induced STAT3 activation and cytokine production, blocks NF-κB activation, and selectively prevents NFAT nuclear translocation without affecting Calcineurin activity. Cucurbitacin R inhibits TNF-α production and Nitric-oxide synthase-2 expression. Cucurbitacin R reduces joint damage, soft tissue swelling, paw edema, ear edema, inflammatory cell infiltration, and epithelial thickness. Cucurbitacin R can be used for research on arthritis and delayed-type hypersensitivity .
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Cat. No.: HY-P991595
CAS No.: 2790610-50-1

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

HB-0017 is a humanized IgG1κ monoclonal antibody inhibitor, targeting IL-17A. HB-0017 inhibits the IL-6 secretion induced by IL-17A with an IC50 of 2.09 nM. HB-0017 significantly decreases ear thickness in Imiquimod (HY-B0180)-induced psoriasis-like mice model and alleviates inflammations in IL-17A-induced arthritis and air pouch mice model. The isotype control for the HB-0017 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-183367
CAS No.: 1504587-21-6
Research Areas:  

Inflammation/Immunology

Anti-inflammatory agent 115 is a potent anti-inflammatory agent. Anti-inflammatory agent 115 reduces secretion of myeloperoxidase (MPO), TNF-α, IL-1β, and IL-6. Anti-inflammatory agent 115 decreases ear tissue thickness and neutrophil infiltration in 12-O-tetradecanoylphorbol-13-acetate (TPA) (HY-18739)-induced topical edema in mice. Anti-inflammatory agent 115 can be used for the research of inflammatory diseases .
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Cat. No.: HY-187467
Target:  

JAK

Research Areas:  

Inflammation/Immunology

Tyk2-IN-28 is an orally active and selective TYK2 inhibitor with an IC50 of 0.9 nM. Tyk2-IN-28 also inhibits JAK2 kinase activity with an IC50 of 4 nM. Tyk2-IN-28 blocks inflammatory cytokine signaling. Tyk2-IN-28 reduces paw swelling in mouse models. Tyk2-IN-28 can be used for research on psoriasis .
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