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Results for "

electrophilic metabolite

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-21065
    Tienilic acid
    2 Publications Verification

    Ticrynafen; ANP 3624

    		 Cytochrome P450 Cardiovascular Disease Metabolic Disease
    Tienilic acid (Ticrynafen; ANP 3624) acts as a diuretic hypotensive agent. However, Tienilic acid induces hepatotoxicity. Tienilic acid is converted into electrophilic metabolites by cytochrome P450 (CYP) in vitro .
    Tienilic acid
  • HY-135235
    Cysteine thiol probe
    1 Publications Verification

    		 Fluorescent Dye Others
    Cysteine Thiol Probe is a thiol-based probe designed to label electrophilic natural products. Cysteine Thiol Probe possesses each of the characteristics of an ideal pharmacophore probe, and has a chromophore. Cysteine Thiol Probe is capable of engaging enone-, β-lactam-, and β-lactone-based electrophilic metabolites .
    Cysteine thiol probe
  • HY-W017187
    2-tert-Butyl-1,4-benzoquinone

    		Bacterial Drug Metabolite Keap1-Nrf2 Heme Oxygenase (HO) Infection
    2-tert-Butyl-1,4-benzoquinone is a food additive oxidant, an electrophilic metabolite of Butylated hydroxyanisole (HY-B1066), and an antibacterial agent. 2-tert-Butyl-1,4-benzoquinone reduces virulence factors, activates Nrf2, and induces S-arylation of its negative regulator Keap1. 2-tert-Butyl-1,4-benzoquinone induces HO-1. 2-tert-Butyl-1,4-benzoquinone exhibits quorum sensing inhibitory activity against Chromobacterium violaceum .
    2-tert-Butyl-1,4-benzoquinone
  • HY-163804
    Cyprocide-B

    		Cytochrome P450 Parasite Others
    Cyprocide-B is activated by Cytochrome P450 and converted to electrophilic metabolites that selectively kill nematodes C. elegans. Cyprocide-B is promising for research of selective nematicide .
    Cyprocide-B
  • HY-21065R
    Tienilic acid (Standard)

    Ticrynafen (Standard); ANP 3624 (Standard)

    		 Cytochrome P450 Reference Standards Metabolic Disease
    Tienilic acid (Standard) is the analytical standard of Tienilic acid. This product is intended for research and analytical applications. Tienilic acid (Ticrynafen; ANP 3624) acts as a diuretic hypotensive agent. However, Tienilic acid induces hepatotoxicity. Tienilic acid is converted into electrophilic metabolites by cytochrome P450 (CYP) in vitro .
    Tienilic acid (Standard)
  • HY-156803
    Estradiol 3,4-quinone

    		Drug Metabolite Cancer
    Estradiol 3,4-quinone (E2-3,4-Q) is a metabolite of Estradiol (HY-B0141). Estradiol 3,4-quinone is a highly electrophilic compound and can induce cancer initiating mutations .
    Estradiol 3,4-quinone

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