17 Results for "

glucagon antibody

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "glucagon antibody" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-W018781
CAS No.: 1670-14-0
Target:  

Ser/Thr Protease

Research Areas:  

Cancer

Benzamidine hydrochloride is a competitive protease inhibitor that blocks the hydrolytic cleavage of glucagon by plasmin, trypsin and thrombin. Benzamidine hydrochloride effectively inhibits the degradation of glucagon by relevant proteases during the collection, storage and analysis of human plasma and blood samples. During in vivo metabolism, Benzamidine hydrochloride undergoes N-hydroxylation and produces multiple metabolites, exhibiting characteristics of delayed excretion or biphasic elimination. Benzamidine hydrochloride only induces slight single-strand DNA breaks at high concentrations and shows no significant genotoxic potential overall. Benzamidine hydrochloride may interfere with the detection of some glucagon antisera, but does not affect key antigen-antibody affinity at specific concentrations. Benzamidine hydrochloride can be used as a stabilizer in glucagon radioimmunoassays to ensure the accuracy and recovery rate of detection results .
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4
4 Cited Publications
Cat. No.: HY-125913
CAS No.: 618-39-3
Target:  

Ser/Thr Protease

Research Areas:  

Inflammation/Immunology

Benzamidine is a competitive protease inhibitor that blocks the hydrolytic cleavage of glucagon by plasmin, trypsin and thrombin. Benzamidine effectively inhibits the degradation of glucagon by relevant proteases during the collection, storage and analysis of human plasma and blood samples. During in vivo metabolism, Benzamidine undergoes N-hydroxylation and produces multiple metabolites, exhibiting characteristics of delayed excretion or biphasic elimination. Benzamidine only induces slight single-strand DNA breaks at high concentrations and shows no significant genotoxic potential overall. Benzamidine may interfere with the detection of some glucagon antisera, but does not affect key antigen-antibody affinity at specific concentrations. Benzamidine can be used as a stabilizer in glucagon radioimmunoassays to ensure the accuracy and recovery rate of detection results .
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4
4 Cited Publications
Cat. No.: HY-W087937
CAS No.: 206752-36-5
Synonyms: Benzenecarboximidamide hydrochloride hydrate
Benzamidine (Benzenecarboximidamide) hydrochloride hydrate is a competitive protease inhibitor that blocks the hydrolytic cleavage of glucagon by plasmin, trypsin and thrombin. Benzamidine hydrochloride hydrate effectively inhibits the degradation of glucagon by relevant proteases during the collection, storage and analysis of human plasma and blood samples. During in vivo metabolism, Benzamidine hydrochloride hydrate undergoes N-hydroxylation and produces multiple metabolites, exhibiting characteristics of delayed excretion or biphasic elimination. Benzamidine hydrochloride hydrate only induces slight single-strand DNA breaks at high concentrations and shows no significant genotoxic potential overall. Benzamidine hydrochloride hydrate may interfere with the detection of some glucagon antisera, but does not affect key antigen-antibody affinity at specific concentrations. Benzamidine hydrochloride hydrate can be used as a stabilizer in glucagon radioimmunoassays to ensure the accuracy and recovery rate of detection results .
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2
2 Cited Publications
Cat. No.: HY-P81160
Synonyms: glucagon like peptide-1 receptor; GLP 1 R; GLP 1 receptor; GLP 1R; Glp1r; GLP; glp1r; glucagon like peptide 1 receptor; RATGL1RCP; Glip; MGC138331; GLP-1-R; GLP1R_HUMAN; glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R; GLP-1R; Precursor.

Host:  

Rabbit

Application:  

WB, IHC-P, IHC-F, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P99357
CAS No.: 1452387-69-7
Synonyms: REGN1193; Anti-GCGR Reference antibody (crotedumab)

Target:  

GCGR

Research Areas:  

Metabolic Disease

Crotedumab (REGN1193) is a fully human IgG4 monoclonal antibody that binds and inhibits glucagon receptor (GCGR), with a KD of 0.1 nM. Crotedumab can be used for the research of diabetes .
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Cat. No.: HY-P99383
CAS No.: 1233956-13-2
Synonyms: REMD-477; AMG-477

Target:  

GCGR

Research Areas:  

Metabolic Disease

Volagidemab is an antagonistic glucagon receptor (GCGR) monoclonal antibody (mAb). Volagidemab can be used in the research of type 1 diabetes (T1D) .
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Cat. No.: HY-P990013
CAS No.: 2642374-02-3
Synonyms: Glutazumab; GMA-102; GMA-105

Target:  

GCGR

Research Areas:  

Metabolic Disease

Gulgafafusp alfa is a human IgG2κ antibody targeting the glucagon-like peptide 1 receptor GLP1R .
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Cat. No.: HY-W018781R
CAS No.: 1670-14-0
Research Areas:  

Cancer

Benzamidine hydrochloride (Standard) is the analytical standard of Benzamidine (hydrochloride). This product is intended for research and analytical applications. Benzamidine hydrochloride is a competitive protease inhibitor that blocks the hydrolytic cleavage of glucagon by plasmin, trypsin and thrombin. Benzamidine hydrochloride effectively inhibits the degradation of glucagon by relevant proteases during the collection, storage and analysis of human plasma and blood samples. During in vivo metabolism, Benzamidine hydrochloride undergoes N-hydroxylation and produces multiple metabolites, exhibiting characteristics of delayed excretion or biphasic elimination. Benzamidine hydrochloride only induces slight single-strand DNA breaks at high concentrations and shows no significant genotoxic potential overall. Benzamidine hydrochloride may interfere with the detection of some glucagon antisera, but does not affect key antigen-antibody affinity at specific concentrations. Benzamidine hydrochloride can be used as a stabilizer in glucagon radioimmunoassays to ensure the accuracy and recovery rate of detection results .
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Cat. No.: HY-P992006

Target:  

GCGR

Research Areas:  

Inflammation/Immunology

Anti-Glucagon Antibody is an anti-Glucagon antibody. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
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Cat. No.: HY-P81242
Synonyms: GCG antibody; glucagon

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P85994
Synonyms: GCG; glucagon;

Host:  

Mouse

Application:  

IHC-P, ICC/IF, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P85183
Synonyms: GCG; glucagon

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human

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Cat. No.: HY-P87875
Synonyms: Pro-glucagon, GCG

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P810878
Synonyms: glucagon receptor, GL-R, GCGR

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P992007
Synonyms: RN909

Target:  

GCGR

Research Areas:  

Metabolic Disease

PF-06293620 (RN909) is a monoclonal antibody antagonist of the glucagon receptor. PF-06293620 produces dose-dependent, durable lowering of fasting plasma glucose and reduces HbA1c levels. PF-06293620 can be used for the research of type 2 diabetes mellitus .
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Cat. No.: HY-D3172
CAS No.: 1180112-32-6
Synonyms: glucagon Yellow
BD-105 (Glucagon Yellow) is a glucagon-binding fluorescent probe with a KD value of 13.3 μM. BD-105 exhibits changes in fluorescence intensity upon interaction with glucagon, and colocalizes with glucagon in cells and tissues. BD-105 is a selective cell stain that labels glucagon-secreting cells without staining insulin-secreting cells or non-endocrine control cells. BD-105 serves as an imaging reagent for glucagon in live cells and tissues (Ex/Em = 540 nm/580 nm) .
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Cat. No.: HY-P811065
Synonyms: glucagon-like peptide 1 receptor, GLP-1 receptor, GLP-1-R, GLP-1R, Glp1r

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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