1. Metabolic Enzyme/Protease
  2. Ser/Thr Protease
  3. Benzamidine hydrochloride

Benzamidine hydrochloride 

Cat. No.: HY-W018781
Handling Instructions

Benzamidine hydrochloride is an reversible competitive inhibitor of trypsin-like serine proteases, with Kis of 97 µM, 21 µM, 20 µM and 110 µM for uPA, trypsin, tryptase and factor Xa, respectively.

For research use only. We do not sell to patients.

Benzamidine hydrochloride Chemical Structure

Benzamidine hydrochloride Chemical Structure

CAS No. : 1670-14-0

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Description

Benzamidine hydrochloride is an reversible competitive inhibitor of trypsin-like serine proteases, with Kis of 97 µM, 21 µM, 20 µM and 110 µM for uPA, trypsin, tryptase and factor Xa, respectively[1].

IC50 & Target

Ki: 97 µM (uPA), 21 µM (trypsin), 20 µM (tryptase), 110 µM (factor Xa)[1]

In Vitro

Benzamidine hydrochloride has weak inhibition for tPA and thrombin, with Kis of 750 µM and 320 µM, respectively[1].

Molecular Weight

156.61

Formula

C₇H₉ClN₂

CAS No.

1670-14-0

SMILES

[H]Cl.N=C(C1=CC=CC=C1)N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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Keywords:

BenzamidineSer/Thr ProteaseSerine proteasesSerine endopeptidasesThreonine proteasestrypsin-likeserineproteasesuPAtrypsintryptasefactor Xaurokinase-type ,plasminogenactivatorInhibitorinhibitorinhibit

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Benzamidine hydrochloride
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HY-W018781
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