1233956-13-2
1233956-13-2
Chemical Structure
Volagidemab
Synonym(s): REMD-477; AMG-477
- CAS. Nr.: 1233956-13-2
- Formula:N/A
- Molecular Weight:(147.02 kDa)
SMILES: [Volagidemab]
Biological Activity: Volagidemab is an antagonistic glucagon receptor (GCGR) monoclonal antibody (mAb). Volagidemab can be used in the research of type 1 diabetes (T1D)[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Volagidemab | ≥99.0% | Volagidemab is an antagonistic glucagon receptor (GCGR) monoclonal antibody (mAb). Volagidemab can be used in the research of type 1 diabetes (T1D). | ||||||||||||||||||||
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References
- [1]. Pettus J, et al. Glucagon receptor antagonist volagidemab in type 1 diabetes: a 12-week, randomized, double-blind, phase 2 trial. Nat Med. 2022 Oct;28(10):2092-2099. [Content Brief]
- [2]. Wang MY, et al. Glucagon receptor antibody completely suppresses type 1 diabetes phenotype without insulin by disrupting a novel diabetogenic pathway. Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):2503-8. [Content Brief]
