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Results for "

gram positive

" in MedChemExpress (MCE) Product Catalog:

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GMP Molecules

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0522

Ampicillin 75+ Cited Publications D-(-)-α-Aminobenzylpenicillin	Bacterial Antibiotic	Infection
Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.

HY-B0522A

Ampicillin sodium 75+ Cited Publications D-(-)-α-Aminobenzylpenicillin sodium salt	Bacterial Antibiotic	Infection
Ampicillin sodium (D-(-)-α-Aminobenzylpenicillin sodium salt) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria .

HY-Y0264

4-Hydroxybenzoic acid	Endogenous Metabolite Bacterial	Infection
4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC₅₀ of 160 μg/mL.

HY-B1174

Bekanamycin Kanamycin B	Antibiotic Bacterial	Infection
Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic produced by Streptomyces kanamyceticus, against an array of Gram-positive and Gram-negative bacterial strain .

HY-W013699

Chlorhexidine diacetate 10+ Cited Publications	Environmental Pollutants Antibiotic Necroptosis Bacterial Apoptosis	Infection
Chlorhexidine diacetate is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine diacetate binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine diacetate has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine diacetate can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis) .

HY-B0522B

Ampicillin trihydrate 75+ Cited Publications D-(-)-α-Aminobenzylpenicillin trihydrate	Bacterial Antibiotic	Infection
Ampicillin trihydrate (D-(-)-α-Aminobenzylpenicillin trihydrate) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.

HY-A0246A

Flucloxacillin sodium 1 Publications Verification	Bacterial Antibiotic	Infection
Flucloxacillin sodium is an active antibiotic against gram-positive and gram-negative bacteria .

HY-100584

Davercin Erythromycin Cyclocarbonate	Bacterial Antibiotic	Infection
Davercin (Erythromycin Cyclocarbonate), derivative of Erythromycin, which is active against Gram-positive and some Gram-negative microorganisms.

HY-112853

Fosmidomycin sodium salt 2 Publications Verification FR-31564	Bacterial Antibiotic	Infection
Fosmidomycin sodium salt is a phosphonic acid antibiotic and a antimalarial agent, which is active against both Gram-negative and Gram-positive bacteria.

HY-A0253

Cefacetrile Cephacetrile; Cephacetril	Bacterial Antibiotic	Infection
Cefacetrile (Cephacetrile) is a broad-spectrum antibiotic that is effective in gram-positive and gram-negative bacterial infection .

HY-N1416

Pogostone 2 Publications Verification	Bacterial Apoptosis Autophagy	Infection Inflammation/Immunology Cancer
Pogostone is isolated from patchouli oil with anti-bacterial and anti-cancer activities. Pogostone inhibits both gram negative and gram positive bacteria, also show inhibitory effect on corynebacterium xerosis with a MIC value of 0.098 µg/ml . Pogostone induces cell apoptosis and autophagy .

HY-135659

BSH-IN-1 2 Publications Verification	Bacterial	Infection
BSH-IN-1 is a potent and covalent inhibitor of gut bacterial recombinant bile salt hydrolases (BSHs) with IC₅₀s of 108 nM and 427 nM for B. longum BSH (Gram positive) and B. theta BSH (Gram negative), respectively .

HY-B1599

Chloramphenicol palmitate	Bacterial Antibiotic	Infection
Chloramphenicol palmitate is an orally active prodrug of Chloramphenicol (HY-B0239), obtained from the esterification reaction between the agent and Palmitic acid (HY-N0830). Chloramphenicol palmitate is rapidly and completely hydrolyzed by intestinal esterase, releasing Chloramphenicol. Chloramphenicol is an orally effective broad-spectrum antibiotic .

HY-B1908

Midecamycin 2 Publications Verification SF-837; Antibiotic SF-837	Bacterial Antibiotic	Infection
Midecamycin, an acetoxy-substituted macrolide antibiotic, is tested against gram-positive and gram-negative bacteria.

HY-101128

Bicyclomycin benzoate 2 Publications Verification FR2054	Bacterial Antibiotic	Infection
Bicyclomycin benzoate is an antibiotic exhibiting activity against a broad spectrum of Gram-negative bacteria and against the Gram-positive bacterium.

HY-N0195

Azomycin 2-Nitroimidazole	MOFs Bacterial Antibiotic	Infection
Azomycin (2-Nitroimidazole) is an antibiotic which can be active against aerobic Gram-positive and Gram-negative bacteria.

HY-N5127

Nonacosane	Bacterial	Infection
Nonacosane, isolated from Baphia massaiensis, exhibits weak activities against E. coli, B. subtilis, P. aeruginosa and S. aureus .

HY-121368

Mahanine	Parasite	Infection Inflammation/Immunology Cancer
Mahanine is a carbazole alkaloid with various biological properties. Mahanine is a potent anticancer agent against different types of cancer cells. Mahanine exhibits antileishmanial activity and can be used for Leishmania infection research research.

HY-A0246

Flucloxacillin 1 Publications Verification	Antibiotic Bacterial	Infection
Flucloxacillin is an active antibiotic against gram-positive and gram-negative bacteria .

HY-121144

Cefazedone Refosporen	Antibiotic Bacterial	Infection
Cefazedone (Refosporen) is a first-generation cephalosporin antibiotic. Cefazedone is active against both Gram-positive and Gram-negative bacteria .

HY-W074648

Antibacterial agent 18	MOFs Bacterial	Infection
Antibacterial agent 18 is a multi-arm AIE molecule extracted from patent CN110123801A, compound 23. Antibacterial agent 18 can be used for resisting Gram-positive and Gram-negative bacteria. Antibacterial agent 18 can be conjugated in the cell wall of rigid arm configuration insertion bacterium, and block cell wall turns sugar and turns peptide process, to inhibit or kill bacterium .

HY-B2094

Arbekacin	Antibiotic Bacterial	Infection
Arbekacin, an aminoglycoside antibiotic, exhibits broad antimicrobial activities against not only Gram-positive bacteria but also Gram-negative bacteria .

HY-W002677

Fluoroquinolonic acid	Antibiotic Bacterial	Infection
Fluoroquinolonic acid is a bacteriostatic antibiotic. Fluoroquinolonic acid has broad-spectrum activity against Gram-positive and Gram-negative bacteria .

HY-125654A

Olanexidine hydrochloride	Bacterial	Infection
Olanexidine hydrochloride is a monobiguanide compound with bactericidal activity. Olanexidine probably binds to the cell membrane, destroys membrane integrity. Olanexidine hydrochloride is active against a wide range of bacteria, including Gram-positive and Gram-negative bacteria. Olanexidine exhibits the bactericidal concentration of 109 μg/mL for Gram-positive bacilli .

HY-N15551

Armeniaspirol C	Bacterial	Infection
Armeniaspirol C is a potent antibacterial agent targeting Gram-positive bacteria. Armeniaspirol C is is promising for research of infections caused by multidrug-resistant Gram-positive bacteria .

HY-121922

Dienone B Dibromoverongiaquinol	Bacterial	Infection
Dienone B is a marine algicide with antibiotic activity against both Gram-positive and Gram-negative marine bacteria .

HY-D1697

OGDA	Fluorescent Dye	Infection
OGDA is a green fluorescent D-amino acid. OGDA is suitable for labeling peptidoglycan in Gram-positive and Gram-negative bacteria .

HY-P5592A

Temporin B acetate	Bacterial	Infection
Temporin B acetate is an antimicrobial peptide against Gram-positive bacteria. Temporin B acetate is less active against Gram-negative bacteria .

HY-121348

Ficellomycin U-47929	Antibiotic Bacterial DNA/RNA Synthesis	Infection
Ficellomycin is a nitrogen-containing bicyclic antibiotic with strong activity against Gram-positive bacteria, including multidrug-resistant strains of Staphylococcus aureus. Ficellomycin works by inducing the formation of defective 34S DNA fragments, which interfere with the semi-conservative DNA replication process. These fragments lack the ability to integrate into larger DNA segments and eventually form a complete bacterial chromosome. Ficellomycin can be used in research for various bacterial diseases .

HY-W013699R

Chlorhexidine diacetate (Standard)	Reference Standards Antibiotic Bacterial Necroptosis Apoptosis	Infection
Chlorhexidine diacetate (Standard) is the analytical standard of Chlorhexidine diacetate (HY-W013699). This product is intended for research and analytical applications. Chlorhexidine diacetate is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine diacetate binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine diacetate has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine diacetate can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis) .

HY-B0960R

Sulfabenzamide (Standard) N-Sulfanilylbenzamide (Standard)	Reference Standards Bacterial Autophagy MDM-2/p53 Caspase PARP DNA-PK Akt	Infection Cancer
Sulfabenzamide (N-Sulfanilylbenzamide) (Standard) is the analytical standard of Sulfabenzamide (HY-B0960). This product is intended for research and analytical applications. Sulfabenzamide is a sulfonamide antibacterial agent. Sulfabenzamide exhibit antibacterial activity against Staphylococcus aureus (ATCC 25923) and Escherichia coli (ATCC 8739). Sulfabenzamide can promote autophagic cell autophagy in breast cancer cells through p53/ DRAM pathway. Sulfabenzamide increases caspase-3 activity, deactivates PARP1 and DNA-PK, downregulates AKT1 and AKT2. Sulfabenzamide can be used for the researches of breast cancer and bacterial infections .

HY-132915

*Anti gram-positive/negative bacteria agent 1*	Bacterial	Infection
Anti gram-positive/negative bacteria agent 1 is an antibiotic conjugate with an artificial MECAM-based siderophore.

HY-N3296

Meridinol (-)-Meridinol	Bacterial Fungal	Inflammation/Immunology
Meridinol ((-)-Meridinol) shows antimicrobial activity against a wide range of gram-positive and gram-negative bacteria and fungi.

HY-P5592

Temporin B	Bacterial	Infection
Temporin B is an antimicrobial peptide against Gram-positive bacteria. Temporin B is less active against Gram-negative bacteria .

HY-164003

Dapabutan	Bacterial	Infection
Dapabutan is an antimicrobial agent with activity against Gram-positive bacteria .

HY-113687

T145	Bacterial	Infection
T145 is an oxazolidinone with antibacterial activity that inhibits growth of gram negatives (K. pneumoniae, A. baumannii, P. aeruginosa and E. cloacae), gram positives (E. faecalis and S. aureus) and acid fast pathogens (Mab, Mav and Mtb) .

HY-125608

Tiacumicin C Lipiarmycin B3	Antibiotic Bacterial	Infection
Tiacumicin C (Lipiarmycin B3) is an antibiotic with activity against Gram-positive bacteria. Tiacumicin C is employed in research related to bacterial infections .

HY-N1416R

Pogostone (Standard)	Reference Standards Bacterial Apoptosis Autophagy	Infection Inflammation/Immunology
Pogostone (Standard) is the analytical standard of Pogostone. This product is intended for research and analytical applications. Pogostone is isolated from patchouli oil?with anti-bacterial and anti-cancer activities.?Pogostone inhibits both gram negative and gram positive bacteria, also show inhibitory effect on corynebacterium xerosis with a MIC value of 0.098 μg/ml .?Pogostone induces cell apoptosis and autophagy .

HY-105533

BAYV-3522	Bacterial	Infection
BAYV-3522 is an orally effective cephalosporin. BAYV-3522 has antibacterial activity against Gram positive bacteria and some respiratory pathogens. BAYV-3522 can be used in the research of infectious conditions .

HY-126662

Netzahualcoyone	Antibiotic Bacterial	Infection
Netzahualcoyone is a triterpenoid compound isolated from the Celastraceae plant family. Netzahualcoyone exhibits broad-spectrum antibiotic activity against Gram-positive bacteria and yeasts, but is not active against Gram-negative bacteria. Netzahualcoyone can be utilized in the development of antibiotics and for studying antimicrobial mechanisms .

HY-P10539

Hp1404	Bacterial	Infection
Hp1404 is a novel cationic antimicrobial peptide. Hp1404 has specific inhibitory activity against Gram-positive bacteria, including Staphylococcus aureus (MRSA) resistant to Laburnetin (HY-N7382). Hp1404 has antimicrobial activity, low toxicity, and is not prone to drug resistance, and can be used in the research of antimicrobial agents .

HY-N5127R

Nonacosane (Standard)	Reference Standards Bacterial	Infection
Nonacosane (Standard) is the analytical standard of Nonacosane. This product is intended for research and analytical applications. Nonacosane, isolated from Baphia massaiensis, exhibits weak activities against E. coli, B. subtilis, P. aeruginosa and S. aureus .

HY-P10694

IDR-HH2	Bacterial	Infection Inflammation/Immunology
IDR-HH2 is an immunomodulatory peptide with the ability to modulate the host cytokine/chemokine environment. IDR-HH2 can promote the adhesion of monocytes and THP-1 cells to fibronectin. Additionally, IDR-HH2 possesses antibacterial activity, inhibiting the activity of both P. aeruginosa and S. aureus with MIC values of 75 µg/mL and 38 µg/mL, respectively .

HY-N14529

Oganomycin B	Bacterial	Infection
Oganomycin B is more stable than cephalosporin and resistant to Gram-positive and negative bacteria. And it is more effective against Gram-negative bacteria than Gram-positive bacteria .

HY-122328

Flambamycin	Antibiotic Bacterial	Infection
Flambamycin is an antibiotic found in Streptomyces hygroscopicus DS 23230 strain, active against Gram-positive and Gram-negative cocci and some Gram-positive rods. Flambamycin can be used in research on antibiotic screening .

HY-N13883

Aerocavin	Antibiotic Bacterial	Infection
Aerocavin is an antibiotic that is active against both Gram-positive and Gram-negative bacteria in vitro .

HY-N14477

Saframycin Mx2	Bacterial	Infection
Saframycin Mx2 has anti-Gram-positive bacteria and Gram-negative bacteria effects .

HY-N14755

Juvenimicin A2	Bacterial	Infection
Juvenimicin A2 can resist Gram-positive bacteria and individual Gram-negative bacteria .

HY-N14333

Halomicin A	Antibiotic Bacterial	Infection
Halomicin A is an ansamycin antibiotic. Halomicin A has activity against Gram-positive and Gram-negative bacteria (individual) .

HY-N3640

Crenatine	Bacterial	Infection
Crenatine is an antibacterial agent. Crenatine is more effective against *Gram-positive* than *Gram-negative* bacteria .

Cat. No.	Product Name	Type

HY-D0215

Safranin

Safranine T

Fluorescent Dyes

Safranin (Safranin T) is an important and classical phenazinium dye. Safranin has been extensively used in the academic field as a spectroscopic probe and indicator. Safranin possesses a planar structure and cationic charge. Safranin can readily intercalate into biological macromolecules, including DNA and proteins. Safranin has antibacterial effects against gram-positive bacteria (S. aureus). Safranin can be used as a redox indicator in the determination of metal ion concentration .

HY-D0128

4-Methylherniarin 7-Methoxy-4-methylcoumarin	Fluorescent Dyes
4-Methylherniarin (7-Methoxy-4-methylcoumarin) is a coumarin derivative and fluorescent label, has an antimicrobial activitiy against both gram positive and gram negative bacterial stains. 4-Methylherniarin displays good activity against B. subtilis and S.sonnei with IC₅₀ values of 11.76 μg/ml and 13.47 μg/ml .

HY-D2208

SYTM Green 1 Publications Verification	Fluorescent Dyes
SYTM Green is a cell impermeant DNA dye that fluoresces green by binding to dsDNA (Ex/Em=503/530 nm). SYTM Green can also be used to stain bacteria, including Gram-positive and Gram-negative bacteria. Note: SYTM Green cannot penetrate living cells, and this product is equivalent to (Ex/Em=488/530 nm) .

HY-107864

Erythrosine B free acid Tetraiodofluorescein	Fluorescent Dyes
Erythrosine B free acid is a visibly red dye with colorimetric and fluorescent properties that serves as an important dye for many Gram-positive and -negative bacteria. Erythrosine B free acid can be used for live/dead determination in both colorimetric and fluorescence-based assays for low, medium and high-throughput experimentation .

HY-D2987

BacGO	Fluorescent Dyes
BacGO is a highly selective, wash free fluorescent probe for Gram positive bacteria. BacGO binds to the carbohydrate structure in peptidoglycan through boric acid and exhibits depolymerization induced luminescence (DIE) properties. BacGO can be used for imaging complex environmental samples (such as activated sludge) and flat plate bacteria without affecting bacterial activity .

HY-B0450AG

Ciclopirox olamine

Ciclopirox ethanolamine; HOE 296

Fluorescent Dyes

Ciclopirox (olamine) (GMP) is Ciclopirox olamine (HY-B0450A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic .

HY-D3390

sCy5DA	Fluorescent Dyes
sCy5DA is a is a fluorescent D-amino acid . sCy5DA incorporates into bacterial peptidoglycan layers and cross-links via transpeptidase action, replacing peptidoglycan stem peptide D-amino acids. sCy5DA labels live bacterial cell walls, nascent peptidoglycan biosynthesis sites, and diverse bacterial species including Gram-negative, Gram-positive, and mycobacteria (Ex/Em = 646/665 nm) .

HY-D3389

sCy5DL-amide

Fluorescent Dyes

sCy5DL-amide is an amidated fluorescent D-amino acid conjugated to Sulfo-Cyanine 5, and a peptidoglycan labeling agent. sCy5DL-amide incorporates into bacterial peptidoglycan cell wall via transpeptidase-mediated reactions, replacing the fourth or fifth D-amino acid of the peptidoglycan stem peptide for visualization of nascent peptidoglycan biosynthesis. sCy5DL-amide produces clear cell outline, septum labeling, and high localization density in Bacillus subtilis, including a 'V-shape' pattern at cell-cell contact areas. sCy5DL-amide exhibits robust incorporation into Gram-positive bacteria and mycobacteria, with reduced incorporation into Gram-negative bacteria (Ex/Em = 646/666 nm) .

HY-107864R

Erythrosine B free acid (Standard)

Tetraiodofluorescein (Standard)

Fluorescent Dyes

Erythrosine B free acid (Standard) is the analytical standard of Erythrosine B (free acid) (HY-107864). This product is intended for research and analytical applications. Erythrosine B free acid is a visibly red dye with colorimetric and fluorescent properties that serves as an important dye for many Gram-positive and -negative bacteria. Erythrosine B free acid can be used for live/dead determination in both colorimetric and fluorescence-based assays for low, medium and high-throughput experimentation .

Cat. No.	Product Name	Type

HY-P3466

Nisin Z	Biochemical Assay Reagents
Nisin Z is an antimicrobial and anti-inflammatory peptide. Nisin Z is effective against Gram-positive bacteria and fungi, such as C. albicans .

HY-B2237A

Lysozyme chloride 5+ Cited Publications	Biochemical Assay Reagents
Lysozyme chloride is a bactericidal enzyme, and it lyses gram-positive bacteria. Lysozyme chloride can also be used for the research of HIV infection and pulmonary emphysema .

HY-141633

Sucrose monolaurate

Biochemical Assay Reagents

Sucrose monolaurate is a glycolipid surfactant . Sucrose monolaurate interacts with bacterial DNA, disrupts cell membrane permeability, and exerts excellent inhibitory and bactericidal effects against a variety of foodborne pathogens (especially Gram-positive bacteria). Sucrose monolaurate significantly reduces liquid surface tension, and acts as a synergist for chlorine-based disinfectants in food cleaning and disinfection to improve the removal efficiency of pathogens on the surface of agricultural products .

HY-W250308A

ε-Poly-L-lysine hydrochloride (MV 2000-5000)

Epsilon-polylysine hydrochloride (MV 2000-5000); ε-Polylysine hydrochloride (MV 2000-5000); ε-PL hydrochloride (MV 2000-5000)

Biochemical Assay Reagents

ε-Poly-L-lysine (Epsilon-polylysine; ε-Polylysine) hydrochloride (MV 2000-5000) is a polycationic antibacterial agent with broad-spectrum activity against Gram-positive bacteria, Gram-negative bacteria, fungi, yeasts and specific bacteriophages. ε-Poly-L-lysine hydrochloride (MV 2000-5000) exerts bactericidal effects through mechanisms such as disrupting microbial membranes, inducing ROS production, inhibiting metabolism and spore germination. ε-Poly-L-lysine hydrochloride (MV 2000-5000) also regulates the expression of multiple key genes including sodA, oxyR and recA. ε-Poly-L-lysine hydrochloride (MV 2000-5000) exhibits properties such as low eukaryotic cytotoxicity, thermal stability and pH stability, and supports tissue regeneration and anti-tumor applications. ε-Poly-L-lysine hydrochloride (MV 2000-5000) can be applied in research fields including bacterial and fungal infections, diabetic ulcers, and methicillin-resistant Staphylococcus aureus infections .

HY-W016473

Adamantane-carboxylic acid

Biochemical Assay Reagents

Adamantane-carboxylic acid is a compound with inhibitory activity against microorganisms. Although its specific target has not been clearly defined, it can inhibit Gram-positive bacteria and some Gram-negative bacteria. It forms a 1-monoacylglycerol derivative through a direct reaction with glycidol, and exerts its antibacterial effect by mechanisms such as altering the permeability of the bacterial cell membrane. This compound can be used in the research of antibacterial agents in the food and cosmetic industries to reduce harmful microbial flora and extend the shelf life of products .

HY-Y0850U5

PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization)

Polyvinyl alcohol (Mw 27000, 98-99% hydrolyzed, ~600 polymerization); Poly(Ethenol) (Mw 27000, 98-99% hydrolyzed, ~600 polymerization)

Biochemical Assay Reagents

PVA (Polyvinyl alcohol) (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) is a nonionic ethanol homopolymer with hydrophilicity, water solubility and biodegradability. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) exhibits biocompatibility, non-toxicity and non-carcinogenicity, as well as antibacterial activity against Gram-positive bacteria, Gram-negative bacteria and fungal strains. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) can serve as a solubilizer, stabilizer, mucoadhesive agent and sustained-release agent, and has a synergistic solubilizing effect on voriconazole/sulfobutyl ether β-cyclodextrin complexes. By stabilizing such complexes, PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) forms freeze-thaw hydrogels with high mucoadhesion, sustained drug release and ex vivo corneal permeability. When compounded with hyaluronic acid hydrogels, PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) supports chondrocyte growth in vitro, and also forms complexes with Cu ²⁺, Co ²⁺, Ni ²⁺ and Zn ²⁺ ions. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) can be used in studies related to fungal keratitis, bacterial infections and fungal infections .

HY-W354851

Pisiferic acid	Biochemical Assay Reagents
Pisiferic acid is an antibacterial agent with inhibitory activity against Gram-negative/positive bacteria such as P. vulgaris, S. aureus and B. subtilis. Pisiferic acid can be used to study bacterial infections .

HY-D0008

Brilliant green	Biochemical Assay Reagents
Brilliant green is a cationic dye used to color silk and wool. Brilliant green inhibits propagation of mold, intestinal parasites and fungus. Brilliant green is effective against Gram-positive bacteria .

HY-60325

2-Amino-4-chloropyridine	Biochemical Assay Reagents
2-Amino-4-chloropyridine is a key intermediate. 2-Amino-4-chloropyridine derivatives exhibit antibacterial activity against Gram-positive bacteria, Gram-negative bacteria, and fungi .

HY-B0450AG

Ciclopirox olamine

Ciclopirox ethanolamine; HOE 296

Biochemical Assay Reagents

HY-W353258R

Moxifloxacin hydrochloride monohydrate (Standard)

BAY 12-8039 monohydrate (Standard)

Biochemical Assay Reagents

Moxifloxacin hydrochloride (BAY 12-8039) monohydrate (Standard) is the analytical standard of Moxifloxacin hydrochloride monohydrate. This product is intended for research and analytical applications. Moxifloxacin hydrochloride monohydrate is a blood-brain barrier-permeable, orally active topoisomerase II/IV inhibitor and a fluoroquinolone antibiotic. Moxifloxacin hydrochloride monohydrate disrupts bacterial DNA replication, transcription, repair and chromosome segregation processes. Moxifloxacin hydrochloride monohydrate exhibits activity against Gram-positive bacteria, Gram-negative bacteria, anaerobes, atypical pathogens, drug-resistant respiratory pathogens, Mycobacterium tuberculosis, mycoplasmas and Ureaplasma urealyticum.

HY-69174

1-Amino-2,5-anhydro-1-deoxy-D-mannitol

Biochemical Assay Reagents

1-Amino-2,5-anhydro-1-deoxy-D-mannitol is a potent antibacterial compound with antibacterial activity against a variety of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE). The application potential of 1-Amino-2,5-anhydro-1-deoxy-D-mannitol lies in its ability to effectively combat common drug-resistant bacterial infections. 1-Amino-2,5-anhydro-1-deoxy-D-mannitol may become an emerging antibacterial agent in clinical inhibition.

Cat. No.	Product Name

HY-K1097

Gram Stain Kit
MCE Gram Stain Kit can be used to differentiate between Gram-negative and Gram-positive bacteria.

HY-K1006

Penicillin-Streptomycin (100×), Sterile Maximum Cited Publications 92 Publications Verification
MCE Penicillin-Streptomycin (100×), Sterile is used to prevent bacterial contamination of cell culture due to their effective combined action against gram-positive and gram-negative bacteria, which contains 10,000 units/mL of penicillin and 10 mg/mL of streptomycin.

HY-K1008

Gentamicin-Amphotericin B (500×), Sterile 1 Publications Verification
MCE Gentamicin-Amphotericin B (500×), sterile is used to prevent contamination of cell culture due to their effective combined action against gram-positive bacteria, gram-negative bacteria, fungi and yeasts, which contains 5 mg/mL of gentamicin, and 125 μg/mL of amphotericin.

HY-K1050

Gentamicin, Sterile 3 Publications Verification
MCE Gentamicin, Sterile (10 mg/mL) is a filtered and sterilized antibiotic solution that can be used directly in cell culture. Gentamicin acts by binding to the 30S subunit of the bacterial ribosome leading to inhibition of protein synthesis and death in susceptible bacteria, mainly for gram-negative and gram-positive bacteria.

HY-K1010

Penicillin-Streptomycin-Glutamine (100×), Sterile 1 Publications Verification
MCE Penicillin-Streptomycin-Glutamine (100×), sterile is used to prevent bacterial contamination of cell culture due to their effective combined action against gram-positive and gram-negative bacteria, which contains 10,000 units/mL of penicillin, 10 mg/mL of streptomycin, and 29.2 mg/mL of Glutamine.

HY-K0014

Penicillin-Streptomycin-Neomycin (PSN) (100×), Sterile
MCE Penicillin-Streptomycin-Neomycin (PSN) (100×), Sterile is used to prevent bacterial contamination of cell culture due to their effective combined action against gram-positive and gram-negative bacteria, which contains 5,000 units/mL of penicillin, 5 mg/mL of streptomycin, and 10 mg/mL of Neomycin.

HY-K1057

Puromycin, Sterile 60+ Cited Publications
Puromycin is an aminonucleoside antibiotic produced by Streptomyces alboniger. It inhibits protein synthesis by disrupting peptide transfer on ribosomes, causing premature chain termination during translation. It can kill most gram-positive bacteria and various animal or insect cells.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-Y0264

4-Hydroxybenzoic acid	Classification of Application Fields Plants Endogenous metabolite Infection Human Gut Microbiota Metabolites Monophenols Microorganisms Leguminosae Ketones, Aldehydes, Acids Phenols Glycyrrhiza uralensis Fisch. Disease Research Fields Source Classification	Endogenous Metabolite Bacterial
4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC₅₀ of 160 μg/mL.

HY-B1174

Bekanamycin Kanamycin B	Infection Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Antibiotic Bacterial
Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic produced by Streptomyces kanamyceticus, against an array of Gram-positive and Gram-negative bacterial strain .

HY-B0132

Norfloxacin 5 Publications Verification MK-0366	Infection Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Source Classification	Bacterial Endogenous Metabolite Antibiotic
Norfloxacin (MK-0366) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase.

HY-B1802A

Tosufloxacin tosylate hydrate 2 Publications Verification A-61827 tosylate hydrate; T-3262	Infection Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Bacterial Antibiotic
Tosufloxacin tosylate hydrate (A-61827) is an orally active fluoroquinolone antibiotic. Tosufloxacin shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .

HY-30219

D-(+)-Phenyllactic acid D-3-Phenyllactic acid	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Source Classification	Bacterial Endogenous Metabolite Bcl-2 Family
D-(+)-Phenyllactic acid is an anti-bacterial agent, excreted by Geotrichum candidum, inhibits a range of Gram-positive from humans and foodstuffs and Gram-negative bacteria found in humans .

HY-142127

Ribostamycin 1 Publications Verification Vistamycin; SF-733	Infection Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Bacterial Antibiotic PDI
Ribostamycin (Vistamycin) is a broad-spectrum aminoglycoside antibiotic. Ribostamycin is effective against Gram-Negative and Gram-Positive bacterial infection. Ribostamycin also inhibits the chaperone activity of PDI .

HY-N1416

Pogostone 2 Publications Verification	Natural Products Entada phaseoloides (L.) Merr. Classification of Application Fields Labiatae Plants Inflammation/Immunology Disease Research Fields Source Classification	Bacterial Apoptosis Autophagy
Pogostone is isolated from patchouli oil with anti-bacterial and anti-cancer activities. Pogostone inhibits both gram negative and gram positive bacteria, also show inhibitory effect on corynebacterium xerosis with a MIC value of 0.098 µg/ml . Pogostone induces cell apoptosis and autophagy .

HY-B1908

Midecamycin 2 Publications Verification SF-837; Antibiotic SF-837	Infection Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Source Classification	Bacterial Antibiotic
Midecamycin, an acetoxy-substituted macrolide antibiotic, is tested against gram-positive and gram-negative bacteria.

HY-N0195

Azomycin 2-Nitroimidazole	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	MOFs Bacterial Antibiotic
Azomycin (2-Nitroimidazole) is an antibiotic which can be active against aerobic Gram-positive and Gram-negative bacteria.

HY-N5127

Nonacosane	Infection Natural Products other families Classification of Application Fields Plants Disease Research Fields Source Classification	Bacterial
Nonacosane, isolated from Baphia massaiensis, exhibits weak activities against E. coli, B. subtilis, P. aeruginosa and S. aureus .

HY-121368

Mahanine	Infection Alkaloids Monophenols Classification of Application Fields Rutaceae Murraya koenigii (L.) Spreng Phenols Plants Inflammation/Immunology Disease Research Fields Indole Alkaloids Source Classification	Parasite
Mahanine is a carbazole alkaloid with various biological properties. Mahanine is a potent anticancer agent against different types of cancer cells. Mahanine exhibits antileishmanial activity and can be used for Leishmania infection research research.

HY-121144

Cefazedone Refosporen	Infection Structural Classification Animals Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Antibiotic Bacterial
Cefazedone (Refosporen) is a first-generation cephalosporin antibiotic. Cefazedone is active against both Gram-positive and Gram-negative bacteria .

HY-N15551

Armeniaspirol C	Microorganisms Antibiotics Source Classification	Bacterial
Armeniaspirol C is a potent antibacterial agent targeting Gram-positive bacteria. Armeniaspirol C is is promising for research of infections caused by multidrug-resistant Gram-positive bacteria .

HY-121922

Dienone B Dibromoverongiaquinol	Structural Classification Animals Source Classification	Bacterial
Dienone B is a marine algicide with antibiotic activity against both Gram-positive and Gram-negative marine bacteria .

HY-Z16210

Nebramycin Ⅴ’ Nebramine factor 5′; 6′′-O-Carbamoyltobramycin	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial
Nebramycin V' (Nebramine factor 5′) is a multi-component aminoglycoside antibiotic with a broad-spectrum activity against Gram-positive and Gram-negative bacteria and mycobacteria .

HY-N10229

Harzianum A	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields Source Classification	Fungal
Harzianum A is a trichothecene compound. Harzianum A has no antibacterial activity against Gram-negative and Gram-positive bacteria, but has antifungal activity. In addition, Harzianum A is cytotoxic to tumor cells .

HY-121348

Ficellomycin U-47929	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial DNA/RNA Synthesis
Ficellomycin is a nitrogen-containing bicyclic antibiotic with strong activity against Gram-positive bacteria, including multidrug-resistant strains of Staphylococcus aureus. Ficellomycin works by inducing the formation of defective 34S DNA fragments, which interfere with the semi-conservative DNA replication process. These fragments lack the ability to integrate into larger DNA segments and eventually form a complete bacterial chromosome. Ficellomycin can be used in research for various bacterial diseases .

HY-N3296

Meridinol (-)-Meridinol	Zanthoxylum bungeanum Maxim. Lignans Rutaceae Phenylpropanoids Plants Source Classification	Bacterial Fungal
Meridinol ((-)-Meridinol) shows antimicrobial activity against a wide range of gram-positive and gram-negative bacteria and fungi.

HY-116271

Sperabillin C	Natural Products Microorganisms Source Classification	Antibiotic Bacterial
Sperabillin C is an antibacterial antibiotic with activity against both Gram-negative and Gram-positive bacteria, including resistant strains of Pseudomonas aeruginosa and Staphylococcus aureus .

HY-165294

Amidinomycin	Microorganisms Antibiotics Source Classification	Bacterial
Amidinomycin is mainly resistant to Gram-positive bacteria (weak) .

HY-N15114

Polymyxin A1	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial
Polymyxin A1 is a heteropeptide antibiotic found in different strains of Bacillus polymyxa, and its effect against Gram-negative bacteria is greater than that against Gram-positive bacteria .

HY-125608

Tiacumicin C Lipiarmycin B3	Microorganisms Antibiotics Source Classification	Antibiotic Bacterial
Tiacumicin C (Lipiarmycin B3) is an antibiotic with activity against Gram-positive bacteria. Tiacumicin C is employed in research related to bacterial infections .

HY-N1416R

Pogostone (Standard)	Structural Classification Natural Products Entada phaseoloides (L.) Merr. Labiatae Plants Source Classification	Reference Standards Bacterial Apoptosis Autophagy
Pogostone (Standard) is the analytical standard of Pogostone. This product is intended for research and analytical applications. Pogostone is isolated from patchouli oil?with anti-bacterial and anti-cancer activities.?Pogostone inhibits both gram negative and gram positive bacteria, also show inhibitory effect on corynebacterium xerosis with a MIC value of 0.098 μg/ml .?Pogostone induces cell apoptosis and autophagy .

HY-126662

Netzahualcoyone	Triterpenes Terpenoids Cassine balae Kosterm. Celastraceae Plants Source Classification	Antibiotic Bacterial
Netzahualcoyone is a triterpenoid compound isolated from the Celastraceae plant family. Netzahualcoyone exhibits broad-spectrum antibiotic activity against Gram-positive bacteria and yeasts, but is not active against Gram-negative bacteria. Netzahualcoyone can be utilized in the development of antibiotics and for studying antimicrobial mechanisms .

HY-N5127R

Nonacosane (Standard)	Natural Products other families Plants Source Classification	Reference Standards Bacterial
Nonacosane (Standard) is the analytical standard of Nonacosane. This product is intended for research and analytical applications. Nonacosane, isolated from Baphia massaiensis, exhibits weak activities against E. coli, B. subtilis, P. aeruginosa and S. aureus .

HY-N14529

Oganomycin B	Microorganisms Antibiotics Other Antibiotics Source Classification	Bacterial
Oganomycin B is more stable than cephalosporin and resistant to Gram-positive and negative bacteria. And it is more effective against Gram-negative bacteria than Gram-positive bacteria .

HY-122328

Flambamycin	Other Terpenoids Structural Classification Microorganisms Terpenoids Source Classification	Antibiotic Bacterial
Flambamycin is an antibiotic found in Streptomyces hygroscopicus DS 23230 strain, active against Gram-positive and Gram-negative cocci and some Gram-positive rods. Flambamycin can be used in research on antibiotic screening .

HY-N13883

Aerocavin	Microorganisms Macrolide Antibiotics Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial
Aerocavin is an antibiotic that is active against both Gram-positive and Gram-negative bacteria in vitro .

HY-N14477

Saframycin Mx2	Quinones Structural Classification Microorganisms Benzene Quinones Source Classification	Bacterial
Saframycin Mx2 has anti-Gram-positive bacteria and Gram-negative bacteria effects .

HY-N14755

Juvenimicin A2	Microorganisms Macrolide Antibiotics Antibiotics Source Classification	Bacterial
Juvenimicin A2 can resist Gram-positive bacteria and individual Gram-negative bacteria .

HY-N14333

Halomicin A	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial
Halomicin A is an ansamycin antibiotic. Halomicin A has activity against Gram-positive and Gram-negative bacteria (individual) .

HY-N3640

Crenatine	Alkaloids Simaroubaceae Plants Quassia undulata (Guill. & Perr.) D.Dietr. Indole Alkaloids Source Classification	Bacterial
Crenatine is an antibacterial agent. Crenatine is more effective against *Gram-positive* than *Gram-negative* bacteria .

HY-129280

Janthinocin A	Microorganisms Antibiotics Other Antibiotics Source Classification	Bacterial
Janthinocin A has strong activity of anti-Gram-positive bacteria and moderate anti-Gram-negative bacteria .

HY-N14128

Cirramycin B1	Microorganisms Macrolide Antibiotics Antibiotics Source Classification	Bacterial
Cirramycin B1 has the activity against Gram-positive bacteria, Gram-negative bacteria and mycoplasmas .

HY-N14677

Pillaromycin A	Microorganisms Antibiotics Other Antibiotics Source Classification	Bacterial
Pillaromycin A has anti-mycobacteria, Gram-positive bacteria and Gram-negative bacteria effects, but the effect of anti-Gram-negative bacteria is weak. Pillaromycin A also has antitumor activity .

HY-N14192

Maltophilin	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Fungal
Maltophilin is a broad-spectrum antifungal antibiotic that has no antibacterial effect against Gram-positive and Gram-negative bacteria .

HY-N14175

Epithienamycin C	Microorganisms Antibiotics Beta-lactam Antibiotics Source Classification	Antibiotic Bacterial
Epithienamycin C is a carbapenem antibiotic. Epithienamycin C has anti-Gram-positive and Gram-negative bacteria activity .

HY-N14174

Epithienamycin A	Microorganisms Antibiotics Beta-lactam Antibiotics Source Classification	Antibiotic Bacterial
Epithienamycin A is a carbapenem antibiotic. Epithienamycin A has anti-Gram-positive bacteria and anti-Gram-negative bacteria activity .

HY-N14998

Damavaricin D	Natural Products Microorganisms Source Classification	Bacterial Fungal
Damavaricin D has anti-Gram-positive bacteria, anti-Gram-negative bacteria and anti-fungal effects .

HY-N14336

Halomicin D	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial
Halomicin D is an ansamycin antibiotic. Halomicin A has activity against Gram-positive and Gram-negative bacteria (individual) .

HY-N14202

Maridomycin V	Microorganisms Macrolide Antibiotics Antibiotics Source Classification	Antibiotic Bacterial
Maridomycin V is a macrolide antibiotic. Maridomycin Vhas the activity against Gram-positive bacteria and mycoplasma. Maridomycin V has the effect of protecting Gram-positive bacterial infection mice .

HY-129673

Sarubicin A U-58431	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial
Sarubicin A (U-58431) is an antibiotic that inhibits Gram-positive and Gram-negative bacteria and has antitumor activity .

HY-N13884

Amythiamicin D	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial
Amythiamicin D is a thiopeptide antibiotic that inhibits the growth of many Gram-positive bacteria, but not Gram-negative bacteria such as E.coli .

HY-N14674

Permetin A	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial
Permetin A is a peptide antibiotic. Permetin A has anti-Gram-negative bacteria, Gram-positive bacteria and anaerobic bacteria activity .

HY-N14334

Halomicin B	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial
Halomicin B is an ansamycin antibiotic. Halomicin B has activity against Gram-positive and Gram-negative bacteria (individual) .

HY-N14338

Sannamycin L	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial
Sannamycin L is an aminoglycoside antibiotic. Sannamycin L has weak antibacterial activity against Gram-positive bacteria and Gram-negative bacteria .

HY-N14335

Halomicin C	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial
Halomicin C is an ansamycin antibiotic. Halomicin C has activity against Gram-positive and Gram-negative bacteria (individual) .

HY-N15036

Olivomycin D	Natural Products Microorganisms Source Classification	Bacterial
Olivomycin D has strong activity against Gram-positive bacteria and weak activity against Gram-negative bacteria .

HY-N14723

Olivomycin B	Microorganisms Antibiotics Other Antibiotics Source Classification	Bacterial
Olivomycin B has strong activity against Gram-positive bacteria and weak activity against Gram-negative bacteria .

HY-N14461

Pluracidomycin D	Natural Products Microorganisms Source Classification	Antibiotic Bacterial
Pluracidomycin D is a carbapenem antibiotic. Pluracidomycin D has anti-Gram-positive bacteria and Gram-negative bacteria activities .

Cat. No.	Product Name	Chemical Structure

HY-A0107S

Tetracycline-d6
Tetracycline-d₆ is the deuterium labeled Tetracycline. Tetracycline is a broad-spectrum antibiotic, exhibiting activity against a wide range of gram-positive and gram-negative bacteria.

HY-B0510S

Trimethoprim-d9
Trimethoprim-d₉ is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment .

HY-17586AS

Dalbavancin-d6
Dalbavancin-d₆ is the deuterium labeled Dalbavancin . Dalbavancin (MDL-63397) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria. Dalbavancin inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively .

HY-B0522S

Ampicillin-d5
Ampicillin-d₅ is the deuterium labeled Ampicillin. Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria .

HY-B0712S

Ceftriaxone-d3 disodium
Ceftriaxone-d₃ (disodium) is the deuterium labeled Ceftriaxone. Ceftriaxone is a third-generation cephalosporin antibiotic with excellent activity against many gram-negative, and reasonable activity against most gram-positive microorganisms. Anti-inflammatory and antioxidant characteristics .

HY-B1923S

Piperacillin-d5
Piperacillin-d₅ is deuterium labeled Piperacillin. Piperacillin is kind of semisynthetic penicillins. Piperacillin has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. Piperacillin has shown greater activity against β-lactamase-producing organisms than the other penicillins .

HY-B0132S

Norfloxacin-d5
Norfloxacin-d₅ is the deuterium labeled Norfloxacin. Norfloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase .

HY-Y0264S1

4-Hydroxybenzoic acid-d4
4-Hydroxybenzoic acid-d₄ is the deuterium labeled 4-Hydroxybenzoic acid. 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL.

HY-B0479S

Thiamphenicol-d3
Thiamphenicol-d₃ is a deuterium labeled Thiamphenicol. Thiamphenicol, a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .

HY-143831S

Cefepime-d8 sulfate

Cefepime-d₈ (BMY-28142-d₈) sulfate is deuterium labeled Cefepime sulfate. Cefepime sulfate is a broad-spectrum, blood-brain barrier-permeable cephalosporin antibiotic with hPON1 inhibitory activity, with an IC₅₀ of 21.115 mM and a K_i of 35.092 mM. Cefepime sulfate inhibits hPON1 via a non-competitive mechanism and blocks GABA_A receptors. Cefepime sulfate penetrates the outer membrane of Gram-negative bacteria, inhibits the growth of Gram-positive and Gram-negative bacteria, and does not induce the production of β-lactamase.

HY-B0519AS

Tylosin-d3

Tylosin-d₃ is the deuterium labeled Tylosin. Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-B0593S

Ceftazidime-d5
Ceftazidime-d₅ (GR20263-d₅) is the deuterium labeled Ceftazidime (HY-B0593). Ceftazidime (GR20263), an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases .

HY-Y0264S

4-Hydroxybenzoic acid-13C6
4-Hydroxybenzoic acid- ¹³C6 is the ¹³C labeled isotope of 4-Hydroxybenzoic acid- ¹³C6.4-Hydroxybenzoic acid is a phenolic derivative of benzoic acid, which can inhibit most Gram-positive bacteria and some Gram-negative bacteria with an IC50 value of 160 μg/mL.

HY-B0510S2

Trimethoprim-d3
Trimethoprim-d₃is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment .

HY-B0275S

Oxytetracycline-d6
Oxytetracycline-d₆ is deuterium labeled Oxytetracycline. Oxytetracycline is an antibiotic belonging to the tetracycline class. Oxytetracycline potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity .

HY-W654100

Cefepime-d3 sulfate

Cefepime-d₃ (BMY-28142-d₃) sulfate is deuterium labeled Cefepime sulfate. Cefepime sulfate is a broad-spectrum, blood-brain barrier-permeable cephalosporin antibiotic with hPON1 inhibitory activity, with an IC₅₀ of 21.115 mM and a K_i of 35.092 mM. Cefepime sulfate inhibits hPON1 via a non-competitive mechanism and blocks GABA_A receptors. Cefepime sulfate penetrates the outer membrane of Gram-negative bacteria, inhibits the growth of Gram-positive and Gram-negative bacteria, and does not induce the production of β-lactamase.

HY-Y0264S2

4-Hydroxybenzoic acid-13c
4-Hydroxybenzoic acid- ¹³C is the ¹³C labeled 4-Hydroxybenzoic acid . 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC₅₀ of 160 μg/mL .

HY-17395S

Terbinafine-d3 hydrochloride

Terbinafine-d₃ hydrochloride is the deuterium labeled Terbinafine hydrochloride. Terbinafine hydrochloride (TDT 067 hydrochloride) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a K_i of 30 nM . Terbinafine hydrochloride also antibacterial activity against certain Gram-positive and Gram-negative bacteria .

HY-B0200S

Cephalexin-d5
Cephalexin-d₅ is deuterium labeled Cephalexin. Cephalexin (Cefalexin; Cephacillin) is a potent, orally active and the first-generation?cephalosporin antibiotic. Cephalexin kills?gram-positive?and some?gram-negative bacteria?by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of?pneumonia,?strep throat, and bacterial endocarditis, et al .

HY-B0275S1

Oxytetracycline-d3

Oxytetracycline-d₃ is the deuterium labeled Oxytetracycline (HY-B0275). Oxytetracycline is an antibiotic belonging to the tetracycline class. Oxytetracycline potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity .

HY-W653936

Cephalexin-d5 hydrate

Cephalexin-d₅ (hydrate) is deuterium labeled Cephalexin (monohydrate). Cephalexin (Cefalexin) monohydrate is a potent, orally active new semisynthetic cephalosporin antibiotic with a broad antibacterial spectrum. Cephalexin (Cefalexin) monohydrate has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin (Cefalexin) monohydrate targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. Cephalexin (Cefalexin) monohydrate is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al .

HY-B1145S

Chlorhexidine-d8 dihydrochloride

Chlorhexidine-d₈ (dihydrochloride) is the deuterium labeled Chlorhexidine dihydrochloride (HY-B1145). Chlorhexidine dihydrochloride is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine dihydrochloride binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine dihydrochloride has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine dihydrochloride can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis) .

HY-136382S

Sulfachloropyridazine-d4
Sulfachloropyridazine-d₄ is the deuterium labeled Sulfachloropyridazine. Sulfachloropyridazine is a broad spectrum sulfonamide used against both Gram-positive and Gram-negative aerobic bacteria .

HY-B1256S

Cefuroxime-d3
Cefuroxime-d₃ is deuterium labeled Cefuroxime (sodium). Cefuroxime sodium is an orally active second-generation cephalosporin antibiotic with increased stability to β-lactamase. Cefuroxime sodium has a broad spectrum activity against Gram-positive and Gram-negative bacteria .

HY-W654101

Cefotaxime-d3
Cefotaxime-d3 is the deuterium labeled Cefotaxime (HY-A0088A). Cefotaxime is the β-lactamase stable cephalosporin and the third-generation cephalosporin antibiotic. Cefotaxime possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .

HY-17395AS

Terbinafine-d7
Terbinafine-d₇ is the deuterium labeled Terbinafine. Terbinafine (TDT 067) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a K_i of 30 nM . Terbinafine also antibacterial activity against certain Gram-positive and Gram-negative bacteria .

HY-W654157

Dicloxacillin-13C4 sodium hydrate
Dicloxacillin- ¹³C₄ sodium hydrate is the ¹³C-labeled Dicloxacillin Sodium hydrate (HY-B0977). Dicloxacillin Sodium hydrate (Dicloxacillin sodium salt monohydrate) is a narrow-spectrum β-Lactam antibiotic of the penicillin class, is used to study infections caused by susceptible Gram-positive bacteria, active against beta-lactamase-producing organisms such as Staphylococcus aureus .

HY-10394S1

Linezolid-d8
PNU-100766-d₈ is deuterated labeled Linezolid (HY-10394). Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics .

HY-B1282S

Sulfaquinoxaline-d4
Sulfaquinoxaline-d₄ is the deuterium labeled Sulfaquinoxaline. Sulfaquinoxaline is an antimicrobial for veterinary use, with activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Sulfaquinoxaline is used to prevent coccidiosis and bacterial infections .

HY-A0088S

Cefotaxime-d3 sodium
Cefotaxime-d₃ (sodium) is the deuterium labeled Cefotaxime (sodium salt). Cefotaxime sodium salt, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .

HY-B0450S1

Ciclopirox-d11 sodium
Ciclopirox-d₁₁ (sodium) is deuterium labeled Ciclopirox. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic .

HY-B0200BS

Cephalexin-d5 monohydrate

Cephalexin-d₅ (monohydrate) is the deuterium labeled Cephalexin monohydrate. Cephalexin monohydrate is a potent, orally active and the first-generation?cephalosporin antibiotic. Cephalexin monohydrate kills?gram-positive?and some?gram-negative bacteria?by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of?pneumonia,?strep throat, and bacterial endocarditis, et al .

HY-B1002S

Oxolinic acid-d5
Oxolinic acid-d₅ is the deuterium labeled Oxolinic acid. Oxolinic acid is an antibiotic against both Gram-negative and Gram-positive bacteria. Oxolinic acid can be used for the research of acute and chronic urinary tract infections. Oxolinic acid is a DNA/RNA synthesis inhibitor. Oxolinic acid acts a dopamine uptake inhibitor and stimulants locomotor effect in mice .

HY-B0398S

Nalidixic Acid-d5

Nalidixic Acid-d₅ is the deuterium labeled Nalidixic acid. Nalidixic acid, a quinolone antibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria .

HY-B0510S3

Trimethoprim-13C3

Trimethoprim- ¹³C₃ is the deuterium labeled Trimethoprim (HY-B0510) . Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim can inhibit infection of Influenza A virus in chick embryo when combinated with zinc .

HY-146535S

Daptomycin-d5 TFA
Daptomycin-d₅ (LY146032-d₅) TFA is the deuterium labeled Daptomycin TFA. Daptomycin TFA is a lipopeptide antibiotic with rapid in vitro bactericidal activity against gram-positive organisms .

HY-B1190S

Cefadroxil-d4 hydrate

Cefadroxil-d₄ (hydrate) is the deuterium labeled Cefadroxil hydrate (HY-B1190A). Cefadroxil hydrate is an orally active broad-spectrum cephalosporin antibiotic. Cefadroxil hydrate inhibits bacterial cell wall synthesis and enhances the expression of glutamate transporter-1. Cefadroxil hydrate is dependent on the intestinal peptide transporter PepT1 for small intestinal absorption. Cefadroxil hydrate has inhibitory and bactericidal activity against a variety of Gram-positive and Gram-negative bacteria and has analgesic effects on neuropathic pain .

HY-B0724BS

Pazufloxacin-d4

Pazufloxacin-d₄ is deuterium labeled Pazufloxacin (HY-B0724B). Pazufloxacin is an orally active fluoroquinolone antimicrobial agent. Pazufloxacin inhibits DNA gyrase with IC₅₀ values of 0.88 μg/mL (E. coli) and 1.9 μg/mL (P. aeruginosa). Pazufloxacin exhibits broad-spectrum antimicrobial activity, with MIC₉₀ values ranging from 0.025 to 100 μg/mL against Gram-positive and Gram-negative bacteria, non-fermenting bacteria, Legionella spp., and anaerobic bacteria. Pazufloxacin is indicated for research on systemic infections, lung infections, urinary tract infections, and Legionella pneumonia .

HY-W743473

Cefetamet-d3

Cefetamet-d₃ (Ro 15-8074-d₃; Deacetoxycefotaxime-d₃) is the deuterium labeled Cefetamet (HY-A0111). Cefetamet (Ro 15-8074) is a cephalosporin antibiotic and the active metabolite of Cefetamet pivoxil (HY-B1894A). Cefetamet binds to bacterial penicillin-binding protein (PBP) (IC₅₀ for PBP3 in Escherichia coli W3110 is 2.5 μg/mL). Cefetamet has significant activity against Gram-negative bacteria such as Enterobacteriaceae, Neisseria species, and Haemophilus influenzae, as well as Gram-positive bacteria such as Streptococcus. Cefetamet kills and lyses Treponema pallidum. Cefetamet can be used in the research of respiratory tract, urinary tract, ear, nose and throat infections, and syphilis .

HY-B0268S1

Enoxacin-d8 hydrochloride

Enoxacin-d₈ (hydrochloride) is deuterium labeled Enoxacin. Enoxacin (AT 2266), a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase (IC₅₀=126 μg/ml) and topoisomerase IV (IC₅₀=26.5 μg/ml). Enoxacin is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. Enoxacin has potent activities against gram-positive and -negative bacteria. Enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing .

HY-B0712S1

Ceftriaxone-13C2,d3 triethylammonium salt

Ceftriaxone-13C2,d3 triethylammonium salt is 13C and deuterated labeled Ceftriaxone (HY-B0712). Ceftriaxone (Ro 13-9904 free acid) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone is a covalent inhibitor of GSK3β with IC₅₀ value of 0.78 mM. Ceftriaxone is an inhibitor of Aurora B. Ceftriaxone has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone can be used in the study of bacterial infections and meningitis .

HY-B1781S

Sulfachloropyridazine-13C6
Sulfachloropyridazine- ¹³C₆ is the ¹³C₆ labeled Sulfachloropyridazine. Sulfachloropyridazine is a broad spectrum sulfonamide used against both Gram-positive and Gram-negative aerobic bacteria.

HY-B0132S1

Norfloxacin-d8
Norfloxacin-d₈ is the deuterium labeled Norfloxacin. Norfloxacin (MK-0366) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase.

HY-19581S

Baquiloprim-d6
Baquiloprim-d₆ is deuterium labeled Baquiloprim. Baquiloprim, an antibiotic, is a selective inhibitor of bacterial dihydrofolate reductases. Baquiloprim possesses in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria .

HY-121341S

Brodimoprim-d6
Brodimoprim-d₆ (Ro 10-5970-d₆) is a deuterium labeled Brodimoprim. Brodimoprim, a trimethoprim analogue, is an orally active dihydrofolate reductase inhibitor. Brodimoprim is highly active against a broad spectrum of gram-negative and gram-positive bacteria .

HY-W750848

Raja 42-d10
Raja 42-d₁₀ is the deuterium labeled Raja 42 (HY-W749146). Raja 42 is a gamma lactam antibiotic. Raja 42 is effective against a variety of different bacterias, including Gram-positive and Gram-negative bacteria, such as C. difficile strains .

HY-B0126S

Marbofloxacin-d8
Marbofloxacin-d₈ is the deuterium labeled Marbofloxacin. Marbofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent, which has a broad spectrum bactericidal activity and good efficacy. Marbofloxacin can be used for the research of infections by Gram-positive and Gram-negative bacteria and Mycoplasma .

HY-B0126AS

Marbofloxacin-d8 hydrochloride
Marbofloxacin-d₈ (hydrochloride) is deuterium labeled Marbofloxacin (hydrochloride). Marbofloxacin hydrochloride is a third generation fluoroquinolone and orally active antimicrobial agent, which has a broad spectrum bactericidal activity and good efficacy. Marbofloxacin hydrochloride can be used for the research of infections by Gram-positive and Gram-negative bacteria and Mycoplasma .

HY-B0450S

Ciclopirox-d11
Ciclopirox-d₁₁ is the deuterium labeled Ciclopirox. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic .

HY-A0107S2

Tetracycline-d6-1
Tetracycline-d₆-1 is deuterated labeled Tetracycline (HY-A0107). Tetracycline is a broad-spectrum antibiotic with oral activity. Tetracycline exhibits activity against a wide range of bacteria including gram-positive, gram-negative bacteria, chlamydiae, mycoplasmas and rickettsiae. Tetracycline can be used for the research of infections .

Cat. No.	Product Name		Classification

HY-W089856

Chlorobutanol hemihydrate		Preservatives
Chlorobutanol hemihydrate is an antimicrobial agent with oral activity, also possessing preservative effects. Chlorobutanol hemihydrate exhibits resistance to a variety of Gram-positive and Gram-negative bacteria, as well as several fungal spores and fungi, and is widely used in the food and cosmetics industries .

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0450AG

Ciclopirox olamine Ciclopirox ethanolamine; HOE 296	Bacterial Fungal Ferroptosis	Infection
Ciclopirox (olamine) (GMP) is Ciclopirox olamine (HY-B0450A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many *Gram-positive* and Gram-negative species pathogenic .

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