10 Results for "

healthy subjects

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "healthy subjects" in MCE Product Catalog:

Cat. No.: HY-100176
CAS No.: 532959-63-0
Purity:  99.64%
Synonyms: 3M-852A
PF-4878691 (3M-852A) is an orally active TLR7 agonist. PF-4878691 has the innate immune response activity, antiviral efficacy against HCV, and can be used for the research of cancer .
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Cat. No.: HY-148795
CAS No.: 2460667-52-9
Ritivixibat is an apical sodium-dependent bile acid transporter (ASBT/IBAT) inhibitor. Ritivixibat blocks ASBT/IBAT function, thereby reducing bile acid reabsorption, regulating bile acid homeostasis and alleviating liver injury. Ritivixibat protects cholangiocytes from damage caused by cytotoxic bile acids. Ritivixibat is applicable to research related to primary sclerosing cholangitis .
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Cat. No.: HY-145461
CAS No.: 1421593-78-3
Synonyms: 5-Hydroxy lenalidomide
Target:  

Drug Metabolite

Research Areas:  

Others

Hydroxy lenalidomide (5-Hydroxy lenalidomide) is a metabolite of lenalidomide that is present as a minor component in plasma and excreta, accounting for less than 5% of the total radioactivity, following oral administration of lenalidomide in healthy male subjects.
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Cat. No.: HY-16525
CAS No.: 701909-57-1
XEN-2174 is a noradrenaline transporter (NET) inhibitor. XEN-2174 inhibits the reuptake of noradrenaline through non-competitive inhibition, increasing the concentration of noradrenaline in the synaptic cleft, thereby activating α2-adrenergic receptor at the spinal level and exerting analgesic effects. XEN-2174 exhibits long-lasting analgesic effects in models of neuropathic pain and postoperative pain in rats. XEN-2174 can be used in pain research .
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Cat. No.: HY-124041
CAS No.: 70267-76-4
Target:  

Drug Metabolite

p-Hydroxybestatin is an active metabolite of Bestatinc (HY-B0134) that can be found in serum from muscular dystrophic patients and from healthy subjects dosed with Bestatin .
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Cat. No.: HY-100176R
CAS No.: 532959-63-0
Synonyms: 3M-852A (Standard)
PF-4878691 (Standard) is the analytical standard of PF-4878691. This product is intended for research and analytical applications. PF-4878691 (3M-852A) is an orally active TLR7 agonist. PF-4878691 has the innate immune response activity, antiviral efficacy against HCV, and can be used for the research of cancer .
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Cat. No.: HY-19904B
CAS No.: 872260-19-0
Synonyms: (+)-LY2409021
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

(+)-Adomeglivant ((+)-LY2409021) is a potent and selective glycogenotropin receptor antagonist with glucose-lowering activity. (+)-Adomeglivant reduces fasting blood glucose levels in both healthy subjects and patients with type 2 diabetes. The use of (+)-Adomeglivant can help investigate the mechanisms of hyperglycemia in type 2 diabetes. The antagonistic effect of (+)-Adomeglivant makes it challenging to assess the metabolic consequences of postprandial hyperglycemia .
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Cat. No.: HY-181571
CAS No.: 2545665-56-1
PDE4-IN-33 is a phosphodiesterase 4 (PDE4) inhibitor. PDE4-IN-33 reduces uric acid levels. PDE4-IN-33 PDE4-IN-33 can be used for the research of hyperuricemia and gout .
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Cat. No.: HY-P992486

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

XKH001 is a recombinant humanized IgG1 monoclonal antibody targeting IL-25. XKH001 has low immunogenicity. XKH001 can be used for the research of type 2 inflammatory diseases .
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Cat. No.: HY-111282
CAS No.: 85394-14-5
Target:  

Dipeptidyl Peptidase

Research Areas:  

Endocrinology

MK-789 is a competitive reversible inhibitor of dehydropeptidase I (DHP-I). MK-789 competitively blocks the entry of N-formimidoylthienamycin into proximal tubular cells, thereby inhibiting its renal metabolism. MK-789 shifts the renal excretion pathway of N-formimidoylthienamycin to glomerular filtration only, increasing its urinary recovery rate and renal clearance. MK-789 is applicable to studies on renal metabolism and pharmacokinetics .
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