10 Results for "

hemolytic anemia

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "hemolytic anemia" in MCE Product Catalog:

Cat. No.: HY-P990706
CAS No.: 2490217-42-8
Synonyms: ALPN-303

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Povetacicept (ALPN-303) is an engineered Fc fusion protein containing the TACI domain, and acts as a dual APRIL/BAFF antagonist. The Kd value of Povetacicept for human BAFF is 59.3 pM, while its Kd value for human APRIL is 1.00 pM. Povetacicept reduces the activation, proliferation, differentiation and survival of B cells, and inhibits the production of immunoglobulins and autoantibodies. Povetacicept can be used in research related to autoimmune hemolytic anemia, immune thrombocytopenia, systemic lupus erythematosus, lupus nephritis and myasthenia gravis .
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Cat. No.: HY-P990025
CAS No.: 2579031-19-7
Synonyms: ARGX-117

Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Empasiprubar (ARGX-117) is a humanized inhibitory monoclonal antibody targeting complement C2. Empasiprubar binds to the Sushi-2 domain of C2, preventing the formation of C3 pre convertase and inhibiting the activation of classical and lectin pathways upstream of C3 activation. Empasiprubar can prevent complement mediated autoimmune hemolytic anemia and antibody mediated organ transplant rejection. Empasiprubar can prevent neuroglial lymphoconjunctival injury in GM1 antibody mediated mouse models .
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Cat. No.: HY-135884
CAS No.: 2283422-04-6
Purity:  99.12%
Synonyms: AG-946; PKR activator 2
Target:  

Pyruvate Kinase

Research Areas:  

Cardiovascular Disease

Tebapivat (PKR activator 2) is a potent pyruvate kinase-R (PKR) activator extracted from patent WO2019035863A1, compound 385 .
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Cat. No.: HY-10545A
CAS No.: 40372-00-7
Purity:  99.89%
Target:  

HBV HCV

Research Areas:  

Infection

Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin hydrochloride is a Ribavirin proagent, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia .
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Cat. No.: HY-10545
CAS No.: 119567-79-2
Target:  

HBV HCV

Research Areas:  

Infection

Taribavirin is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin, is a ribavirin proagent, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia .
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Cat. No.: HY-59228
CAS No.: 39856-50-3
Research Areas:  

Cardiovascular Disease

5-Bromo-2-nitropyridine serves as a synthetic intermediate for pharmaceutical, pesticide and dye products, and also acts as an irritant. 5-Bromo-2-nitropyridine oxidizes hemoglobin to methemoglobin, causing cell and tissue damage as well as oxidative hemolysis .
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Cat. No.: HY-135883
CAS No.: 2283420-62-0
Target:  

Pyruvate Kinase

Research Areas:  

Cardiovascular Disease

PKR activator 1 is a potent pyruvate kinase-R (PKR) activator extracted from patent WO2019035865A1, compound E7-93 .
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Cat. No.: HY-P991898
Synonyms: RD126

Target:  

CD19

Research Areas:  

Inflammation/Immunology

IASO-782 (RD126) is a fully human monoclonal antibody targeting human CD19. The Fc segment of IASO-782 is mutated to enhance antibody-dependent cell-mediated cytotoxicity (ADCC) while maintaining the integrity of other Fc segment functions, such as ADCP. IASO-782 effectively eliminates CD19+ B cells, plasmablasts, and some plasma cells, thereby reducing or completely eliminating autoreactive antibodies produced by these cells. IASO-782 can be used for the study of immune thrombocytopenic purpura (ITP), warm autoimmune hemolytic anemia (wAIHA) and systemic lupus erythematosus (SLE).
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Cat. No.: HY-10545AR
CAS No.: 40372-00-7
Research Areas:  

Infection

Taribavirin hydrochloride (Standard) is the analytical standard of Taribavirin hydrochloride (HY-10545A). This product is intended for research and analytical applications. Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin hydrochloride is a Ribavirin proagent, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia .
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Cat. No.: HY-182506
CAS No.: 64118-86-1
Synonyms: BM 12.531
Azimexon (BM 12.531) is an orally active immunomodulator with radioprotective and antitumor activities. Azimexon prolongs survival in multiple mouse models, enhances immunity and hematopoiesis, and alleviates radiation injury and tumor metastasis. Azimexon causes reversible hemolytic anemia in rats and dogs, and exerts therapeutic activity against adjuvant-induced arthritis in rats. Azimexon can be used for the research of lung carcinoma, leukemia, multiple myeloma, lung tumor, arthritis, breast cancer and AIDS‑related complex .
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