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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
human calcium sensing receptor
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "human calcium sensing receptor" in MCE Product Catalog:
30
Target:
Research Areas:
NPS-2143 (SB-262470A), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 (SB-262470A) blocks increases in cytoplasmic Ca 2+ concentrations (IC50=43 nM) elicited by activating the Ca 2+ receptor in HEK 293 cells expressing the human Ca 2+ receptor .
30
30 Cited Publications
Synonyms: SB-262470A hydrochloride
Target:
Research Areas:
NPS-2143 hydrochloride (SB-262470A hydrochloride), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 hydrochloride (SB-262470A hydrochloride) blocks increases in cytoplasmic Ca 2+ concentrations (IC50=43 nM) elicited by activating the Ca 2+ receptor in HEK 293 cells expressing the human Ca 2+ receptor .
Cat. No.: HY-P4376A
Cat. No.: HY-P4376
CAS No.: 16869-42-4
Cat. No.: HY-15106
CAS No.: 351490-26-1
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Research Areas:
SB-423557 is an orally active calcium-sensing receptor (CaR) antagonist (IC50=520 nM), precursor of SB-423562 (IC50=73 nM). SB-423557 is well tolerated in human and increases plasma concentrations of exogenous parathyroid hormone (PTH) and stimulates bone formation .
Cat. No.: HY-P86831
Synonyms: Ca sensing receptor antibody; Ca2+ sensing receptor 1 antibody; Ca2+ sensing receptor antibody; calcium sensing receptor antibody; CAR antibody; CaSR antibody; CASR_human antibody; EIG8 antibody; Extracellular calcium sensing receptor antibody; Extracellular calcium sensing receptor [Precursor] antibody; Ca sensing receptor antibody; Ca2+ sensing receptor 1 antibody; Ca2+ sensing receptor antibody; calcium sensing receptor antibody; CAR antibody; CaSR antibody; CASR_human antibody; EIG8 antibody; Extracellular calcium sensing receptor antibody; Extracellular calcium sensing receptor [Precursor] antibody; Extracellular calcium-sensing receptor antibody; FHH antibody; FIH antibody; GPRC2A antibody; HHC antibody; HHC1 antibody; Hypocalciuric hypercalcemia 1 antibody; Hypocalciuric hypercalcemia 1 severe neonatal hyperparathyroidism antibody; MGC138441 antibody; NSHPT antibody; Parathyroid Ca(2+) sensing receptor 1 antibody; Parathyroid Cell calcium sensing receptor antibody; Parathyroid Cell calcium-sensing receptor antibody; PCAR 1 antibody; PCaR1 antibody;
Cat. No.: HY-P79408
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CASR; Parathyroid Ca(2+)-sensing receptor 1; Prev. HHC1; Hypocalciuric Hypercalcemia 1; Prev. HHC; calcium-sensing receptor; GPRC2A; HYPOC1; Extracellular calcium-sensing receptor; PCaR1; NSHPT; EIG8; FHH; CaSR; Parathyroid Cell calcium-sensing receptor 1
Species:
Human
Source:
HEK293
Cat. No.: HY-P11832
CAS No.: 3057162-39-4
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Research Areas:
Cat. No.: HY-P4376B
Cat. No.: HY-10007R
CAS No.: 284035-33-2
Synonyms: SB-262470A (Standard)
Target:
Research Areas:
NPS-2143 (Standard) is the analytical standard of NPS-2143 (HY-10007). This product is intended for research and analytical applications. NPS-2143 (SB-262470A), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 (SB-262470A) blocks increases in cytoplasmic Ca2+ concentrations (IC50=43 nM) elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
