28 Results for "

hydrogel networks

" in MedChemExpress (MCE) Product Catalog:
Products (28)

28 Results for "hydrogel networks" in MCE Product Catalog:

Cat. No.: HY-W048825
CAS No.: 87512-31-0
Research Areas:  

Others

Fmoc-Ala-Ala-OH is a self-assembling fluorenylmethoxycarbonyl dipeptide, a small amphiphilic building block composed of a dipeptide linked to a fluorenylmethoxycarbonyl (Fmoc) group. Under conditions of pH < 4, Fmoc-Ala-Ala-OH spontaneously assembles to form a nanofiber network, constructing a hydrogel scaffold with a water content exceeding 99% (w/w). The fibers have a diameter of approximately 22 nm, matching the size of extracellular matrix (ECM) components. Fmoc-Ala-Ala-OH supports cell adhesion, proliferation, and maintains of cell phenotype. Fmoc-Ala-Ala-OH's function is to mimic the ECM, providing a 3D growth microenvironment for cells, and Fmoc-Ala-Ala-OH is primarily used in tissue engineering and 3D cell culture, particularly suitable for in vitro culture studies of cells such as chondrocytes[1] .
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Cat. No.: HY-112624J
CAS No.: 9004-54-0
Synonyms: Dextran 4; Dextran D4; Dextran T4(MW 3200-4800)
Dextran 4,000 is a mucus rheology modifier. The dextran molecules in Dextran 4,000 can reduce the cross-link density of mucus through osmotic effects and hydrogen bond substitution, and reduce viscoelasticity and improve the mucociliary/cough clearance index by destroying the DNA-mucin network structure in mucus. Dextran 4,000 has the ability to improve the rheological properties and clearance ability of cystic fibrosis (CF) sputum, and can be used in the study of inhalation therapy or aerosol delivery of mucostatic respiratory diseases. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
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Cat. No.: HY-112624E
CAS No.: 9004-54-0
Synonyms: Dextran 0.8; Dextran D0.8; Dextran T0.8(MW 640-960)
Dextran T0.8 (Dextran 0.8; Dextran T0.8(MW 640-960)) is a food additive with a porous network structure that exhibits strong hydration capacity and low browning activity. Dextran T0.8 (MW 800) can improve the coagulation of dairy products and is used as a prebiotic in baked goods. Dextran T0.8 (MW 800) is non-toxic to HeLa cells at a concentration of ~500 μg/mL and has a low relative browning rate in the Maillard reaction. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
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Cat. No.: HY-78985
CAS No.: 554-95-0
Synonyms: Trimesic acid
Benzene-1,3,5-tricarboxylic acid (Trimesic acid) is a rigid planar small-molecule scaffold and crosslinker. Benzene-1,3,5-tricarboxylic acid induces bicyclic peptides to adopt a planar conformation, so as to maximize surface area and bind to the flat protein surfaces involved in protein-protein interactions. Benzene-1,3,5-tricarboxylic acid forms ionic crosslinks, hydrogen bonds and π-π bonds with chitosan, thereby constructing a hydrogel network. Benzene-1,3,5-tricarboxylic acid endows chitosan hydrogel systems with specific mechanical properties, enabling sustained release of cancer therapeutic drugs including 5-Fluorouracil (HY-90006) .
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Cat. No.: HY-172380A
PCL-PEG-PCL diacrylate (MW 800) is an amphiphilic triblock copolymer composed of PEG and two polycaprolactones (PCL). PCL-PEG-PCL diacrylate (MW 800) can be cross-linked by free radical polymerization and/or photopolymerization to form a cross-linked hydrogel network .
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Cat. No.: HY-P2632
CAS No.: 289042-25-7
Synonyms: RADA16
Research Areas:  

Neurological Disease

RAD16-I (RADA16) is a non-directed self-assembling peptide hydrogel. Under physiological conditions, RAD16-I spontaneously forms a three-dimensional nanofiber network that mimics the extracellular matrix, and possesses excellent properties such as high water content, biocompatibility and degradability. RAD16-I serves as an ideal scaffold for three-dimensional cell culture. RAD16-I not only maintains cell viability and induces self-organization, but also supports cell adhesion, proliferation, differentiation and insulin secretion, effectively stabilizes islet clusters and promotes directed differentiation of the cardiac lineage. RAD16-I can construct a cell-friendly nano-microenvironment for research related to diseases such as myocardial infarction and diabetes .
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Cat. No.: HY-W097122
CAS No.: 170941-79-4
Research Areas:  

Others

Fmoc-Gly-Gly-Gly-OH is a self-assembling gelator tripeptide modified with 9-fluorenylmethoxycarbonyl (Fmoc). Fmoc-Gly-Gly-Gly-OH forms a secondary supramolecular network through non-covalent interactions in hybrid polymer hydrogel systems. Fmoc-Gly-Gly-Gly-OH contributes to the construction of double-network hydrogels. Fmoc-Gly-Gly-Gly-OH can be used in studies of tissue regeneration and biomedical delivery applications .
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Cat. No.: HY-172380
PCL-PEG-PCL diacrylate (MW 800) is an amphiphilic triblock copolymer composed of PEG and two polycaprolactones (PCL). PCL-PEG-PCL diacrylate (MW 800) can be cross-linked by free radical polymerization and/or photopolymerization to form a cross-linked hydrogel network .
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Cat. No.: HY-Y0425
CAS No.: 623-27-8
Terephthalaldehyde is a crosslinking agent. Terephthalaldehyde forms a crosslinked structure inside the gelatin matrix by forming Schiff base imines with the amino groups of gelatin, thereby constructing a three-dimensional network. Terephthalaldehyde improves the hydrophobicity of the gelatin matrix, delays water vapor penetration and enhances the liquid water resistance of gelatin films. Terephthalaldehyde can be used as a crosslinking agent to prepare crosslinked chitosan hydrogel (CAAT) via ultrasound-induced synthesis. Terephthalaldehyde helps CAAT hydrogels selectively adsorb anionic dyes from aqueous media, including multi-component systems containing cationic dyes. Terephthalaldehyde serves as a starting material for the synthesis of bis-heterocyclic compounds (including bis-thiazole and bis-triazolopyrimidine compounds) .
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Cat. No.: HY-W110540D
CAS No.: 25852-47-5
Poly(ethylene glycol) dimethacrylate (MW 2000) is a photopolymerizable poly(ethylene glycol)-based macromer and biocompatible crosslinking agent with a molecular weight of approximately 2000. Poly(ethylene glycol) dimethacrylate (MW 2000) can form photopolymerized hydrogels. Poly(ethylene glycol) dimethacrylate (MW 2000) can be used for research on tissue engineering and drug delivery .
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Cat. No.: HY-P6299
CAS No.: 944792-75-0
Research Areas:  

Neurological Disease Cancer

MAX8 is a synthetic β-hairpin peptide that folds rapidly and self-assembles into a β-sheet-rich fibrous hydrogel network via non-covalent crosslinking. MAX8 hydrogel exhibits excellent shear-thinning and self-healing properties, enabling precise delivery via syringe and maintaining local retention after implantation. MAX8 hydrogel can uniformly encapsulate cells while preserving their viability and morphology, and protect growth factors (e.g., NGF) and chemotherapeutic drugs from degradation. MAX8 is applicable for spinal cord injury repair, medulloblastoma treatment, and three-dimensional high-throughput drug screening .
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Cat. No.: HY-P10675
Research Areas:  

Metabolic Disease

Peptide K is a self-assembling peptide fiber that can be used to prepare fibrous nanocomposite hydrogels. The fibrous nanocomposite hydrogels have a dynamic network that adapts to cells and enhances cell-matrix and cell-cell interactions, thus significantly promoting the mechanotransduction, metabolic energy, and osteogenesis of encapsulated stem cells .
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Cat. No.: HY-W110540
CAS No.: 25852-47-5
Poly(ethylene glycol) dimethacrylate (MW 550) is a photopolymerizable poly(ethylene glycol)-based macromer and biocompatible crosslinking agent with a molecular weight of approximately 550. Poly(ethylene glycol) dimethacrylate (MW 550) can form photopolymerized hydrogels. Poly(ethylene glycol) dimethacrylate (MW 550) can be used for research on tissue engineering and drug delivery .
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Cat. No.: HY-W110540A
CAS No.: 25852-47-5
Poly(ethylene glycol) dimethacrylate (MW 750) is a photopolymerizable poly(ethylene glycol)-based macromer and biocompatible crosslinking agent with a molecular weight of approximately 750. Poly(ethylene glycol) dimethacrylate (MW 750) can form photopolymerized hydrogels. Poly(ethylene glycol) dimethacrylate (MW 750) can be used for research on tissue engineering and drug delivery .
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Cat. No.: HY-W110540C
CAS No.: 25852-47-5
Poly(ethylene glycol) dimethacrylate (MW 1000) is a photopolymerizable poly(ethylene glycol)-based macromer and biocompatible crosslinking agent with a molecular weight of approximately 1000. Poly(ethylene glycol) dimethacrylate (MW 1000) can form photopolymerized hydrogels. Poly(ethylene glycol) dimethacrylate (MW 1000) can be used for research on tissue engineering and drug delivery .
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Cat. No.: HY-W110540H
CAS No.: 25852-47-5
Poly(ethylene glycol) dimethacrylate (MW 3400) is a photopolymerizable poly(ethylene glycol)-based macromer and biocompatible crosslinking agent with a molecular weight of approximately 3400. Poly(ethylene glycol) dimethacrylate (MW 3400) can form photopolymerized hydrogels. Poly(ethylene glycol) dimethacrylate (MW 3400) can be used for research on tissue engineering and drug delivery .
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Cat. No.: HY-W110540K
CAS No.: 25852-47-5
Poly(ethylene glycol) dimethacrylate (MW 10000) is a photopolymerizable poly(ethylene glycol)-based macromer and biocompatible crosslinking agent with a molecular weight of approximately 10000. Poly(ethylene glycol) dimethacrylate (MW 10000) can form photopolymerized hydrogels. Poly(ethylene glycol) dimethacrylate (MW 10000) can be used for research on tissue engineering and drug delivery .
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Cat. No.: HY-W110540L
CAS No.: 25852-47-5
Poly(ethylene glycol) dimethacrylate (MW 20000) is a photopolymerizable poly(ethylene glycol)-based macromer and biocompatible crosslinking agent with a molecular weight of approximately 20000. Poly(ethylene glycol) dimethacrylate (MW 20000) can form photopolymerized hydrogels. Poly(ethylene glycol) dimethacrylate (MW 20000) can be used for research on tissue engineering and drug delivery .
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Cat. No.: HY-P10699
CAS No.: 487036-63-5
Research Areas:  

Neurological Disease Cancer

MAX1 is a synthetic β-hairpin peptide that folds rapidly and self-assembles into a β-sheet-rich fibrous hydrogel network via non-covalent crosslinking. MAX1 hydrogel exhibits excellent shear-thinning and self-healing properties, enabling precise delivery via syringe and maintaining local retention after implantation. MAX1 hydrogel can uniformly encapsulate cells while preserving their viability and morphology, and protect growth factors (e.g., NGF) and chemotherapeutic drugs from degradation. MAX1 is applicable for spinal cord injury repair, medulloblastoma treatment, and three-dimensional high-throughput drug screening .
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Cat. No.: HY-W110540I
CAS No.: 25852-47-5
Poly(ethylene glycol) dimethacrylate (MW 4000) is a photopolymerizable poly(ethylene glycol)-based macromer and biocompatible crosslinking agent with a molecular weight of approximately 4000. Poly(ethylene glycol) dimethacrylate (MW 4000) can form photopolymerized hydrogels. Poly(ethylene glycol) dimethacrylate (MW 4000) can be used for research on tissue engineering and drug delivery .
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