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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
infectious disease vaccines
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "infectious disease vaccines" in MCE Product Catalog:
2
Target:
Research Areas:
CpG ODN 10101 (ODN 10101; CPG 10101) is a selective agonist targeting TLR9, a synthetic oligodeoxynucleotide modified with phosphate thioester. CpG ODN 10101 activates B cells and plasmacytoid dendritic cells (pDCs), inducing the production of cytokines and chemokines such as interferon-IFN-α, interferon-inducible protein IP-10, and 2'5'-oligoadenylate synthase (2'5'-OAS), regulating innate immunity and promoting Th1 adaptive immune responses. CpG ODN 10101 also possesses antiviral properties and enhances vaccine immunogenicity, making it suitable as an immunomodulator and vaccine adjuvant for vaccine development in chronic hepatitis C and infectious diseases such as melioidosis, pertussis, and respiratory syncytial virus (RSV) .
Cat. No.: HY-101092A
Category:
Triterpenes Quillajaceae Quillaja saponaria Molina Terpenoids Plants Pentacyclic Triterpenoids
Target:
Cat. No.: HY-N16463
CAS No.: 250643-52-8
Category:
Triterpenes Quillajaceae Quillaja saponaria Molina Terpenoids Plants Pentacyclic Triterpenoids
Target:
Cat. No.: HY-178672
CAS No.: 400806-46-4
Synonyms: Anti-Reverse cap analog; m2 7,3′O GpppG
Target:
ARCA (Anti-Reverse cap analog; m2 7,3'OGpppG) is a 5′-cap analog. ARCA carries a methyl group at the 3'-OH position of m7G, which ensures that the cap is ligated to the 5' end of mRNA in the correct orientation during in vitro transcription and prevents reverse ligation. ARCA enhances the translation efficiency and stability of mRNA. In human immature dendritic cells, both the translation efficiency and total protein expression of ARCA-capped mRNA are higher than those of conventional m7GpppG-capped mRNA. ARCA can be used in research related to cancer, infectious diseases and mRNA vaccines .
Cat. No.: HY-L172
150 compounds
Immunity refers to the ability of the body to resist the invasion of pathogenic microorganisms and resist a variety of diseases. Immunocompromised will inevitably lead to a series of diseases. Immunopotentiator are a class of compounds that enhance immune function and induce immune response. Immunopotentiator can activate the proliferation and differentiation of one or more kinds of immune active cells in the body, promote the secretion of lymphocytes, and then enhance the immune function of the body. Immunopotentiator are mainly used in the treatment of tumors, infectious diseases and immunodeficiency diseases. In addition, immunopotentiator are often used as adjuvants in combination with vaccine antigens to enhance the immunogenicity of vaccines.
MCE designs a unique collection of 150 compounds with definite or potential Immunopotentiating effect, mainly targeting the NOD-like Receptor (NLR), Toll-like Receptor (TLR), NF-κB, etc. It is an effective tool for development and research of anti-cancer, anti-infectious diseases and anti-immunodeficiency diseases compounds.
Cat. No.: HY-178672A
Synonyms: Anti-Reverse cap analog triammonium solution (100 mM); m2 7,3′O GpppG triammonium solution (100 mM)
Target:
ARCA (triammonium) solution (100 mM) (Anti-Reverse cap analog triammonium solution (100 mM); m2 7,3'OGppp triammonium solution (100 mM)) is a 5′-cap analog. ARCA (triammonium) solution (100 mM) carries a methyl group at the 3'-OH position of m7G, which ensures that the cap is ligated to the 5' end of mRNA in the correct orientation during in vitro transcription and prevents reverse ligation. ARCA (triammonium) solution (100 mM) enhances the translation efficiency and stability of mRNA. In human immature dendritic cells, both the translation efficiency and total protein expression of ARCA (triammonium) solution (100 mM)-capped mRNA are higher than those of conventional m7GpppG-capped mRNA. ARCA (triammonium) solution (100 mM) can be used in research related to cancer, infectious diseases and mRNA vaccines .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
