QS-S2
QS-S2 is the impurity of QS-21 (HY-101092A). QS-21 is an innate immune system-targeted adjuvant.
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- CAS 番号: 250643-52-8
- 分子式: C87H140O42
- 分子量:1858.02
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
QS-21 is a mixture of QS-21-Xyl (250643-56-2) and QS-21-Api (141256-04-4), with a ratio of 35:65. QS-21 is promising for research of oncology vaccines (e.g., melanoma) and infectious disease vaccines (e.g., HIV, malaria)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 250643-52-8
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分子量 1858.02
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分子式 C87H140O42
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SMILES
O[C@H]([C@@H]([C@H]([C@@H](O1)C)O[C@H]2[C@@H]([C@H]([C@@H](CO2)O)O)O)O)[C@@H]1O[C@H]([C@H]([C@H]([C@H](O3)C)OC(C[C@@H](O)C[C@@H]([C@@H](C)CC)OC(C[C@@H](O)C[C@@H]([C@@H](C)CC)O[C@@H]4O[C@H]([C@@H]([C@H]4O)O)CO)=O)=O)O)[C@@H]3OC([C@]56[C@](CC(C)(CC6)C)([H])C7=CC[C@@]([C@@]8([C@@]([C@@](C)([C@H](CC8)O[C@H]9[C@@H]([C@H]([C@@H]([C@H](O9)C(O)=O)O)O[C@H]%10[C@@H]([C@H]([C@@H](CO%10)O)O)O)O[C@@H]%11O[C@@H]([C@@H]([C@@H]([C@H]%11O)O)O)CO)C=O)([H])CC%12)C)([H])[C@]%12(C)[C@@]7(C[C@H]5O)C)=O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Bankefors J, et al. Structural classification of acyl-substituted Quillaja saponins by electrospray ionisation ion trap multiple-stage mass spectrometry in combination with multivariate analysis. Rapid Commun Mass Spectrom. 2008 Dec;22(23):3851-60. [Content Brief]
[2]. Deng K, et al. Synthesis of QS-21-xylose: establishment of the immunopotentiating activity of synthetic QS-21 adjuvant with a melanoma vaccine. Angew Chem Int Ed Engl. 2008;47(34):6395-8. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)