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Results for "

kallikrein 5

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Kallikrein (6) Protease Activated Receptor (PAR) (1)
By Research Areas:	Inflammation/Immunology (4)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Targets Recommended: Kallikrein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-148949

Kallikrein 5-IN-2	Kallikrein	Others
Kallikrein 5-IN-2 (compound 21) is a selective *Kallikrein* KLK5 inhibitor (pIC₅₀=7.1). KLK5 inhibition may normalise epidermal shedding and reduce the associated inflammation and itching .

HY-148949A

Kallikrein 5-IN-2 TFA	Kallikrein	Others
Kallikrein 5-IN-2 TFA is the TFA salt form of Kallikrein 5-IN-2 (HY-148949). Kallikrein 5-IN-2 TFA is a selective inhibitor for kallikrein 5 (KLK5) with pIC₅₀ of 7.1. Kallikrein 5-IN-2 TFA is non-phototoxic (100 μg/mL) and non-irritant. Kallikrein 5-IN-2 is stable at pH 4-pH 8 under non-oxidative condition. Kallikrein 5-IN-2 is potent in ameliorating the Netherton syndrome .

HY-P990459

*Anti-KLK5/Kallikrein 5* Antibody**	Kallikrein	Inflammation/Immunology
Anti-KLK5/Kallikrein 5 Antibody is a CHO-expressed human antibody that targets **KLK5/Kallikrein 5*. The Anti-KLK5/Kallikrein 5* Antibody has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for the Anti-KLK5/Kallikrein 5 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

HY-150085

GSK951	Kallikrein	Inflammation/Immunology
GSK951 is a potent and selective *Kallikrein-5* (KLK5) inhibitor amenable to epidermal delivery. GSK951 shows an IC₅₀ of 250 pM for KLK5 and greater than 100-fold selectivity over KLK7 and KLK14. GSK951 can reduce transepidermal water loss, and decrease proinflammatory cytokine expression. GSK951 can be used for the researches of inflammation and immunology, such as Netherton syndrome .

HY-P991676

Eflumenibep alfa DS-2325A	Kallikrein	Inflammation/Immunology
Eflumenibep alfa is a *Kallikrein 5* inhibitor with anti-inflammatory activity. Eflumenibep alfa is a fusion protein that combines human SPINK2 with the human IgG1 Fc fragment at the C-terminus .

HY-P11840

KLK5-IN-1	Kallikrein Protease Activated Receptor (PAR)	Inflammation/Immunology
KLK5-IN-1 is a selective kallikrein 5 (KLK5) inhibitor with an IC₅₀ of 14 nM and a K_i of 11 nM. KLK5-IN-1 reduces KLK5-mediated PAR2-dependent calcium mobilization. KLK5-IN-1 improves epithelial barrier integrity. KLK5-IN-1 can be used in research related to atopic dermatitis and Netherton syndrome .

Cat. No.	Product Name	Target	Research Area

HY-P11840

KLK5-IN-1	Kallikrein Protease Activated Receptor (PAR)	Inflammation/Immunology
KLK5-IN-1 is a selective kallikrein 5 (KLK5) inhibitor with an IC₅₀ of 14 nM and a K_i of 11 nM. KLK5-IN-1 reduces KLK5-mediated PAR2-dependent calcium mobilization. KLK5-IN-1 improves epithelial barrier integrity. KLK5-IN-1 can be used in research related to atopic dermatitis and Netherton syndrome .

Cat. No.	Product Name	Target	Research Area	Image

HY-P990459

*Anti-KLK5/Kallikrein 5* Antibody**	Kallikrein	Inflammation/Immunology
Anti-KLK5/Kallikrein 5 Antibody is a CHO-expressed human antibody that targets **KLK5/Kallikrein 5*. The Anti-KLK5/Kallikrein 5* Antibody has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for the Anti-KLK5/Kallikrein 5 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P991676

Eflumenibep alfa DS-2325A	Kallikrein	Inflammation/Immunology
Eflumenibep alfa is a *Kallikrein 5* inhibitor with anti-inflammatory activity. Eflumenibep alfa is a fusion protein that combines human SPINK2 with the human IgG1 Fc fragment at the C-terminus .

Species:	Human (2) Mouse (2)
Tag:	His (4)
Source:	HEK293 (4)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P70939

	Kallikrein-5 Protein, Human (HEK293, His, solution) 1 Publications Verification kallikrein-5; kallikrein-Like Protein 2; KLK-L2; Stratum Corneum Tryptic Enzyme; KLK5; SCTE	Human	HEK293
	The Kallikrein-5 protein may be involved in desquamation, suggesting a role in the process of skin shedding and exfoliation.Its association with desquamation suggests that it plays a role in regulating the removal of dead skin cells, which is critical for skin homeostasis.Kallikrein-5 Protein, Human (HEK293, His, solution) is the recombinant human-derived Kallikrein-5 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70939A

	Kallikrein-5 Protein, Human (HEK293, C-His) kallikrein-5; kallikrein-Like Protein 2; KLK-L2; Stratum Corneum Tryptic Enzyme; KLK5; SCTE	Human	HEK293
	The Kallikrein-5 protein may be involved in desquamation, suggesting a role in the process of skin shedding and exfoliation. Its association with desquamation suggests that it plays a role in regulating the removal of dead skin cells, which is critical for skin homeostasis. Kallikrein-5 Protein, Human (HEK293,C-His) is the recombinant human-derived Kallikrein-5 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P77731

	Kallikrein-5 Protein, Mouse (HEK293, His) kallikrein c; Klnc; KLK5; KLKL2; KLK-L2; SCTE	Mouse	HEK293
	The Kallikrein-5 protein may be involved in desquamation, suggesting a role in the process of skin shedding and exfoliation. Its association with desquamation suggests that it plays a role in regulating the removal of dead skin cells, which is critical for skin homeostasis. Kallikrein-5 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Kallikrein-5 protein, expressed by HEK293 , with C-His labeled tag.

HY-P77731A

	Kallikrein-5 Protein, Mouse (271a.a, HEK293, His) kallikrein c; Klnc; KLK5; KLKL2; KLK-L2; SCTE	Mouse	HEK293
	The Kallikrein-5 protein may be involved in desquamation, suggesting a role in the process of skin shedding and exfoliation. Its association with desquamation suggests that it plays a role in regulating the removal of dead skin cells, which is critical for skin homeostasis. Kallikrein-5 Protein, Mouse (271a.a, HEK293, His) is the recombinant mouse-derived Kallikrein-5 protein, expressed by HEK293 , with C-His labeled tag.

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HY-P83144

	Kallikrein 5 Antibody (YA2889) HK5; kallikrein 5; kallikrein L2; KLK 5; KLK L2; SCTE	WB, ICC/IF, FC	Human, Mouse
	Kallikrein 5 Antibody (YA2889) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Kallikrein 5.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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