27 Results for "

lamivudine

" in MedChemExpress (MCE) Product Catalog:
Products (27)

27 Results for "lamivudine" in MCE Product Catalog:

19
19 Publications Verification
Cat. No.: HY-B0250
CAS No.: 134678-17-4
Synonyms: BCH-189
Research Areas:  

Infection Cancer

Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS .
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2
2 Cited Publications
Cat. No.: HY-B0255
CAS No.: 142340-99-6
Synonyms: GS 0840
Adefovir dipivoxil is an orally active adenosine analog and Adefovir prodrug. Adefovir dipivoxil inhibits DNA synthesis, activates the ATR signaling pathway, and disrupts the KCTD12-CDK1 interaction. Adefovir dipivoxil has antiviral activity against PRV, HBV, and orthopoxviruses. Adefovir dipivoxil has inhibitory effects on both lamivudine-resistant and wild-type strains. Adefovir dipivoxil has antitumor activity against lung and colon cancer .
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Cat. No.: HY-131603
CAS No.: 143188-53-8
Synonyms: 3TCTP
Lamivudine triphosphate (3TCTP) is a phosphorylated Lamivudine (HY-B0250) (a nucleoside analogue). Lamivudine triphosphate inhibits the reverse transcriptase of HIV or HBV viruses to block viral replication by chain termination. Lamivudine triphosphate is also an inhibitor of the RdRp activity of the NS5B subunit of the HCV. Lamivudine triphosphate can be incorporated into the nascent RNA by the SARS-CoV-2 RdRp, thus halting mutations in the nascent SARS-CoV-2 RNA .
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Cat. No.: HY-B0250R
CAS No.: 134678-17-4
Synonyms: BCH-189 (Standard)
Lamivudine (Standard) is the analytical standard of Lamivudine. This product is intended for research and analytical applications. Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS .
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Cat. No.: HY-119691
CAS No.: 193681-12-8
Purity:  ≥95.0%
Synonyms: LY582563; MCC-478
Target:  

HBV

Research Areas:  

Infection

Alamifovir (LY582563; MCC-478), a purine nucleotide analogue proagent, shows potent activity against wild type and lamivudine resistant hepatitis B virus (HBV). Alamifovir has high activity against HBV replication and sustained antiviral effect .
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Cat. No.: HY-B0250A
CAS No.: 173522-96-8
Synonyms: BCH-189 salicylate
Research Areas:  

Infection Cancer

Lamivudine (BCH-189) salicylate is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine salicylate can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS .
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Cat. No.: HY-131603B
CAS No.: 2736455-56-2
Synonyms: 3TCTP TEA
Lamivudine triphosphate (3TCTP) TEA is a phosphorylated Lamivudine (HY-B0250) (a nucleoside analogue). Lamivudine triphosphate TEA inhibits the reverse transcriptase of HIV or HBV viruses to block viral replication by chain termination. Lamivudine triphosphate TEA is also an inhibitor of the RdRp activity of the NS5B subunit of the HCV. Lamivudine triphosphate TEA can be incorporated into the nascent RNA by the SARS-CoV-2 RdRp, thus halting mutations in the nascent SARS-CoV-2 RNA .
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Cat. No.: HY-19447A
CAS No.: 1039623-01-2
Synonyms: LB80380 maleate
Target:  

HBV

Research Areas:  

Infection

Besifovir Dipivoxil maleate (LB80380 maleate) is an oral proagent of LB80317. Besifovir Dipivoxil maleate (LB80380 maleate) is effective in hepatitis B virus (HBV) DNA suppression for both treatment-naive and lamivudine-resistant chronic hepatitis B (CHB) patients in preliminary studies [2]
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Cat. No.: HY-116252
CAS No.: 131086-22-1
Target:  

HIV

Research Areas:  

Infection

(±)-trans-Lamivudine is separated from the salt of (S)-(+) mandelic acid. (±)-trans-Lamivudine forms cocrystals with (S)-BINOL. (±)-trans-Lamivudine is promising for research of human immunodeficiency virus infection .
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Cat. No.: HY-B0255R
CAS No.: 142340-99-6
Synonyms: GS 0840 (Standard)
Adefovir dipivoxil (Standard) is the analytical standard of Adefovir dipivoxil. This product is intended for research and analytical applications. Adefovir dipivoxil is an orally active adenosine analog and Adefovir prodrug. Adefovir dipivoxil inhibits DNA synthesis, activates the ATR signaling pathway, and disrupts the KCTD12-CDK1 interaction. Adefovir dipivoxil has antiviral activity against PRV, HBV, and orthopoxviruses. Adefovir dipivoxil has inhibitory effects on both lamivudine-resistant and wild-type strains. Adefovir dipivoxil has antitumor activity against lung and colon cancer .
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Cat. No.: HY-W654247
CAS No.: 2714473-70-6
Lamivudine- 13C,d2 is the deuterium labeled and 13C-labeled Lamivudine. Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS .
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Cat. No.: HY-135330
CAS No.: 1391052-30-4
Lamivudine- 13C, 15N2 is a labelled impurity of Lamivudine (BCH-189). Lamivudine is a nucleoside reverse transcriptase inhibitors (NRTIs), and can inhibit HIV reverse transcriptase 1/2 and the reverse transcriptase of hepatitis B virus .
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Cat. No.: HY-B0250S
Synonyms: BCH-189-15N,d2
Lamivudine- 15N,d2 is 15N and deuterated labeled Lamivudine (HY-B0250). Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS .
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Cat. No.: HY-B0250S2
CAS No.: 1261394-64-2
Synonyms: BCH-189-13C,15N3
Lamivudine- 13C, 15N3 (BCH-189- 13C, 15N3) is 13C and 15N labeled Lamivudine. Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS .
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Cat. No.: HY-W777161
CAS No.: 1217746-03-6
Synonyms: BCH-189-15N2,13C
Lamivudine- 15N2, 13C (BCH-189- 15N2, 13C) is 13C and 15N labeled Lamivudine .
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Cat. No.: HY-B0250S1
Synonyms: BCH-189-13C,15N2,d2
Lamivudine-13C,15N2,d2 (BCH-189-13C,15N2,d2) is a 13C, 15N, and deuterium labeled Lamivudine (HY-B0250). Lamivudine is an orally active and blood-brain barrier permeable nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine inhibits HIV reverse transcriptase 1 and 2 and hepatitis B virus (HBV) reverse transcriptase .
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Cat. No.: HY-144215
CAS No.: 2761697-69-0
Target:  

HBV

Research Areas:  

Inflammation/Immunology

TLR8 agonist 4 showed effective inhibition on wild-type and drug-resistant (lamivudine and entecavir) HBV strains. The IC50 values are 0.15 and 0.10 respectively μM.
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Cat. No.: HY-Z8369
CAS No.: 160552-55-6
Synonyms: lamivudine sulfoxide
Target:  

Drug Intermediate

Research Areas:  

Others

Lamivudine impurity 6 (lamivudine sulfoxide) is an impurity of Lamivudine.
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Cat. No.: HY-116633
CAS No.: 1820763-99-2
Target:  

Endogenous Metabolite

Research Areas:  

Infection

BCM-599 is a HBV (hepatitis B virus) capsid assembly inhibitor with the activity of inhibiting HBV capsid assembly. BCM-599 showed an IC50 value of 0.88μM and a CC50 value of 144μM in HepG2.2.15 cells. When used in combination with lamivudine, BCM-599 showed a synergistic inhibitory effect on viral concentration. BCM-599 can be used as an effective combined inhibition option for HBV infection .
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Cat. No.: HY-W883657
CAS No.: 145511-98-4
Target:  

Drug Intermediate

Research Areas:  

Others

Lamivudine impurity 4 is an impurity of Lamivudine.
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