173522-96-8
173522-96-8
Chemical Structure
Lamivudine salicylate
Synonym(s): BCH-189 salicylate
- CAS. Nr.: 173522-96-8
- Formula:C15H17N3O6S
- Molecular Weight:367.38
IUPAC Name: 4-amino-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one 2-hydroxybenzoate
InChIKey: GFZSGYKUKMIFHP-UOERWJHTSA-N
SMILES: OC[C@H]1SC[C@@H](N2C(N=C(N)C=C2)=O)O1.OC3=C(C(O)=O)C=CC=C3
Biological Activity: Lamivudine (BCH-189) salicylate is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine salicylate can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS[1][2].
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Lamivudine salicylate | Lamivudine (BCH-189) salicylate is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine salicylate can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS. | |||||||||||||||||||||
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References
- [1]. Li, Y.C., [A clinical study on lamivudine treatment for advanced schistosomisis with chronic B hepatits]. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi, 2013. 25(5): p. 548-9, 551. [Content Brief]
- [2]. Zhang, C.E., et al., [Effects of lamivudine on growth of intestinal characteristic bacteria by microcalorimetry in vitro]. Yao Xue Xue Bao, 2013. 48(10): p. 1590-4. [Content Brief]
