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  3. Lamivudine salicylate

Lamivudine salicylate  (Synonyms: BCH-189 salicylate)

Cat. No.: HY-B0250A
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Lamivudine (BCH-189) salicylate is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine salicylate can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS.

For research use only. We do not sell to patients.

CAS No. : 173522-96-8

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Top Publications Citing Use of Products

    Lamivudine salicylate purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2025 Oct 1;10(1):321.  [Abstract]

    VSMCs were treated with Pi and NRTIs (Lamivudine, 1, 5, 10, or 50 μM), followed by Alizarin Red staining.

    Lamivudine salicylate purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2025 Oct 1;10(1):321.  [Abstract]

    VSMCs treated with Pi and NRTIs (Lamivudine, 1, 5, 10, or 50 μM). followed by calcium content.

    Lamivudine salicylate purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2025 Oct 1;10(1):321.  [Abstract]

    Western blot analysis expression of Runx2, OPN, Smoothelin, SM22α, and LINE1-ORF1 in VSMCs treated with Pi and NRTIs.

    Lamivudine salicylate purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2025 Oct 1;10(1):321.  [Abstract]

    Serum creatinine levels in CKD mice treated with NRTIs (Lamivudine, 1 mg/kg, administered daily intraperitoneal injections).

    Lamivudine salicylate purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2025 Oct 1;10(1):321.  [Abstract]

    NRTIs (Lamivudine, 1 mg/kg, administered daily intraperitoneal injections). Aortic cross-sections from CKD mice or VitD3-overloaded mice were stained using Von Kossa, with n = 3 per group; scale bar = 100 μm.

    Lamivudine salicylate purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2025 Oct 1;10(1):321.  [Abstract]

    NRTIs (Lamivudine, 1 mg/kg, administered daily intraperitoneal injections). Calcium content analysis of aortas from CKD mice or VitD3-overloaded mice (n = 5 per group).

    Lamivudine salicylate purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2025 Oct 1;10(1):321.  [Abstract]

    NRTIs (Lamivudine, 1 mg/kg, administered daily intraperitoneal injections). Immunohistochemical staining of Runx2 and LINE1-ORF1 from CKD mice or VitD3-overloaded mice (n = 3 per group); scale = 50 μm.

    Lamivudine salicylate purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2025 Oct 1;10(1):321.  [Abstract]

    NRTIs (Lamivudine, 1 mg/kg, administered daily intraperitoneal injections). Osteogenic and contractile phenotypic markers, as well as LINE1-ORF1, were analyzed through Western blot and quantitative in CKD mice (n = 3 per group).

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    Description

    Lamivudine (BCH-189) salicylate is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine salicylate can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS[1][2].

    Clinical Trial
    Molecular Weight

    367.38

    Formula

    C15H17N3O6S

    CAS No.
    SMILES

    OC[C@H]1SC[C@@H](N2C(N=C(N)C=C2)=O)O1.OC3=C(C(O)=O)C=CC=C3

    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.

    Purity & Documentation
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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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