1391052-30-4
1391052-30-4
Chemical Structure
Lamivudine-13C,15N2
- CAS No.: 1391052-30-4
- Formula:C713CH9N15N2O4S
- Molecular Weight:246.22
IUPAC Name: (2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl-2-13C-1,3-15N2)-1,3-oxathiolane-2-carboxylic acid
InChIKey: PIIRVEZNDVLYQA-FDHQWECPSA-N
SMILES: O=[13C]1[15N]([C@H]2O[C@@H](C(O)=O)SC2)C=CC(N)=[15N]1
Biological Activity: Lamivudine-13C,15N2 is a labelled impurity of Lamivudine (BCH-189). Lamivudine is a nucleoside reverse transcriptase inhibitors (NRTIs), and can inhibit HIV reverse transcriptase 1/2 and the reverse transcriptase of hepatitis B virus[1][2].
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Lamivudine-13C,15N2 | Lamivudine-13C,15N2 is a labelled impurity of Lamivudine (BCH-189). Lamivudine is a nucleoside reverse transcriptase inhibitors (NRTIs), and can inhibit HIV reverse transcriptase 1/2 and the reverse transcriptase of hepatitis B virus. | |||||||||||||||||||||
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References
- [1]. Li, Y.C., [A clinical study on lamivudine treatment for advanced schistosomisis with chronic B hepatits]. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi, 2013. 25(5): p. 548-9, 551. [Content Brief]
- [2]. Zhang, C.E., et al., [Effects of lamivudine on growth of intestinal characteristic bacteria by microcalorimetry in vitro]. Yao Xue Xue Bao, 2013. 48(10): p. 1590-4. [Content Brief]
Keywords
