2. Anti-infection
  3. HBV
  4. Alamifovir

Alamifovir (LY582563; MCC-478), a purine nucleotide analogue proagent, shows potent activity against wild type and lamivudine resistant hepatitis B virus (HBV). Alamifovir has high activity against HBV replication and sustained antiviral effect.

For research use only. We do not sell to patients.

Alamifovir Chemical Structure

Alamifovir Chemical Structure

CAS No. : 193681-12-8

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Alamifovir Related Antibodies

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Description

Alamifovir (LY582563; MCC-478), a purine nucleotide analogue proagent, shows potent activity against wild type and lamivudine resistant hepatitis B virus (HBV). Alamifovir has high activity against HBV replication and sustained antiviral effect[1][2].

In Vitro

MCC-478 (0-10 μM) has EC50s of 0.027 μM for wild-type HBV, 2.6 μM for M552I, 3.3 μM for M552V, and 2.0 μM for L528M/M552V[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Alamifovir Related Antibodies
Molecular Weight

575.42

Formula

C19H20F6N5O5PS
CAS No.
SMILES

COC1=CC=C(C=C1)SC2=C3N=CN(C3=NC(N)=N2)CCOCP(OCC(F)(F)F)(OCC(F)(F)F)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Alamifovir Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Alamifovir193681-12-8LY582563 MCC-478LY 582563LY-582563MCC478MCC 478MCC-478HBVHepatitis B viruspurine nucleotideprodruglamivudinehepatitis B virusantiviralInhibitorinhibitorinhibit

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