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Cat. No.: HY-W883657

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Lamivudine impurity 4

Name: Lamivudine impurity 4
Brand: MedChemExpress
SKU: HY-W883657
Price: 630.00 USD
Availability: InStock
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Lamivudine impurity 4 is an impurity of Lamivudine.

For research use only. We do not sell to patients.

CAS No.: 145511-98-4
Formula: C₈H₁₁N₃O₄
Molecular Weight:213.19

Storage:

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Data Sheet (239 KB)

Lamivudine impurity 4 Chemical Structure

CAS No.: 145511-98-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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Biological Activity

Description

Lamivudine impurity 4 is an impurity of Lamivudine.

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	0.68 μM Compound: 5	Cytotoxicity against A549 cells after 72 hrs by SRB assay Cytotoxicity against A549 cells after 72 hrs by SRB assay	[PMID: 17419604]
CCRF-CEM	IC₅₀	>1 μM Compound: beta-L-cytosine	Compound was evaluated for cytotoxicity by inhibition of mitochondrial DNA synthesis Compound was evaluated for cytotoxicity by inhibition of mitochondrial DNA synthesis	10.1016/0960-894X(95)00343-R
CCRF-CEM	IC₅₀	0.056 μM Compound: beta-L-cytosine	Cytotoxicity in H1 CEM cells Cytotoxicity in H1 CEM cells	10.1016/0960-894X(95)00343-R
Hepatoma cell line	EC₅₀	0.5 nM Compound: beta-L-cytosine	Antiviral activity against hepatitis B virus in human hepatoma cell line (2.2.15 cells) Antiviral activity against hepatitis B virus in human hepatoma cell line (2.2.15 cells)	10.1016/0960-894X(95)00343-R
SW1573	IC₅₀	2.3 μM Compound: 5	Cytotoxicity against SW1573 cells after 72 hrs by SRB assay Cytotoxicity against SW1573 cells after 72 hrs by SRB assay	[PMID: 17419604]
Vero	IC₅₀	0.1 μM Compound: 25	Cytotoxic effect against vero cells. Cytotoxic effect against vero cells.	[PMID: 8496934]

Chemical Information

CAS No. 145511-98-4
Appearance Solid
Molecular Weight 213.19
Formula C₈H₁₁N₃O₄
SMILES

O=C1N(C=CC(N)=N1)[C@H]2O[C@H](OC2)CO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)