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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
lysosome biogenesis
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "lysosome biogenesis" in MCE Product Catalog:
11
Target:
Research Areas:
HEPES, a nonvolatile zwitterionic chemical buffering agent, is broadly applied in cell culture. HEPES is effective at pH 6.8 to 8.2. HEPES is also a potent inducer of lysosome biogenesis .
11
11 Publications Verification
1
1 Cited Publications
Cat. No.: HY-D0857S
CAS No.: 203805-87-2
Cat. No.: HY-161724
CAS No.: 3027414-04-3
Target:
Research Areas:
TFEB activator 2 is an orally active compound that can cross the blood-brain barrier. TFEB activator 2 can bind to the dopamine transporter (DAT). TFEB activator 2 promotes TFEB nuclear translocation and lysosome biogenesis by targeting the DAT-CDK9-TFEB pathway. TFEB activator 2 has neuroprotective activity and can be used in the research of Alzheimer's disease and other diseases .
Cat. No.: HY-161723
CAS No.: 2358754-22-8
Target:
Research Areas:
LH2-051, a lysosome-enhancing compound (LYEC), is a brain-penetrant dopamine transporter (DAT) inhibitor (Ki: 0.95 μM). LH2-051 inhibits DAT-mediated dopamine uptake with an IC50 of 3.0 μM. LH2-051 promotes nuclear translocation of TFEB and lysosome biogenesis. LH2-051 improves the memory of amyloid precursor protein (APP)/Presenilin 1 (PS1) mice. LH2-051 can be used for the study of Alzheimer’s disease .
Cat. No.: HY-N12434
CAS No.: 2230806-06-9
Synonyms: EOF2
Target:
Cat. No.: HY-161725
CAS No.: 3027413-48-2
Target:
Research Areas:
TFEB activator 3 (compound 45) exhibits TFEB activation and lysosome biogenesis capabilities. TFEB activator 3 has effect on TFEB nuclear translocation with 44% (10μM 3h) and 97 % (30 μM 3h). TFEB activator 3 plays an important role in Alzheimer’s disease (AD). TFEB activator 3 can pass blodd brain barrier .
Cat. No.: HY-108535R
CAS No.: 75277-39-3
Cat. No.: HY-P76171
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: BLOC1S2; CEAP; biogenesis Of Lysosomal Organelles Complex 1 Subunit 2; biogenesis Of lysosome-Related Organelles Complex-1, Subunit 2, Isoform CRA_c; BLOS2; biogenesis Of lysosome-Related Organelles Complex-1 Subunit 2; biogenesis Of lysosome-Related Orga
Species:
Human
Source:
E. coli
Cat. No.: HY-P76171A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BLOC1S2; CEAP; biogenesis Of Lysosomal Organelles Complex 1 Subunit 2; biogenesis Of lysosome-Related Organelles Complex-1, Subunit 2, Isoform CRA_c; BLOS2; biogenesis Of lysosome-Related Organelles Complex-1 Subunit 2; biogenesis Of lysosome-Related Orga
Species:
Human
Source:
E. coli
Cat. No.: HY-P811225
Synonyms: BLOC1S8, My031, DTNBP1, Dysbindin, biogenesis of lysosome-related organelles complex 1 subunit 8, Dysbindin-1, Dystrobrevin-binding protein 1, Hermansky-Pudlak syndrome 7 protein, BLOC-1 subunit 8, HPS7 protein
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
