7365-45-9
7365-45-9
Chemical Structure
HEPES
- CAS No.: 7365-45-9
- Formula:C8H18N2O4S
- Molecular Weight:238.30
IUPAC Name: 2-(4-(2-hydroxyethyl)piperazin-1-yl)ethane-1-sulfonic acid
InChIKey: JKMHFZQWWAIEOD-UHFFFAOYSA-N
SMILES: O=S(CCN1CCN(CCO)CC1)(O)=O
Biological Activity: HEPES, a nonvolatile zwitterionic chemical buffering agent, is broadly applied in cell culture. HEPES is effective at pH 6.8 to 8.2. HEPES is also a potent inducer of lysosome biogenesis[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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HEPES | 99.94% | HEPES, a nonvolatile zwitterionic chemical buffering agent, is broadly applied in cell culture. HEPES is effective at pH 6.8 to 8.2. HEPES is also a potent inducer of lysosome biogenesis. | ||||||||||||||||||||
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HEPES-d18 | 99.89% | HEPES-d18 is the deuterium labeled HEPES. HEPES, a nonvolatile zwitterionic chemical buffering agent, is broadly applied in cell culture. HEPES is effective at pH 6.8 to 8.2. HEPES is also a potent inducer of lysosome biogenesis. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.83
HY-D0859SMOPS-d15 -
Similarity Score 0.82
HY-W0167772,2'-Piperazine-1,4-diyldiethanol -
Similarity Score 0.82
HY-D0858SMES-d13 -
Similarity Score 0.81
HY-W127629MOBS -
Similarity Score 0.80
HY-W3189962-(4-(2-Aminoethyl)piperazin-1-yl)ethan-1-ol -
Similarity Score 0.80
HY-D0859MOPS -
Similarity Score 0.80
HY-D0858MES -
Similarity Score 0.80
HY-D0858AMES monohydrate -
Similarity Score 0.79
HY-W2675322-(4-(2-Hydroxyethyl)piperazin-1-yl)acetic acid -
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References
- [1]. Suzuki T, et al. Nonvolatile buffer coating of titanium to prevent its biological aging and for drug delivery. Biomaterials. 2010;31(18):4818-4828. [Content Brief]
- [2]. Sledź P, et al. An experimental charge density of HEPES. Acta Crystallogr B. 2010;66(Pt 4):482-492. [Content Brief]
- [3]. Tol MJ, et al. HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution. Autophagy. 2018;14(3):437-449. [Content Brief]
